2KMS
 
 | | Combined high- and low-resolution techniques reveal compact structure in central portion of factor H despite long inter-modular linkers | | 分子名称: | Complement factor H | | 著者 | Schmidt, C.Q, Herbert, A.P, Guariento, M, Mertens, H.D.T, Soares, D.C, Uhrin, D, Rowe, A.J, Svergun, D.I, Barlow, P.N. | | 登録日 | 2009-08-04 | | 公開日 | 2009-11-03 | | 最終更新日 | 2020-02-26 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The Central Portion of Factor H (Modules 10-15) Is Compact and Contains a Structurally Deviant CCP Module
J.Mol.Biol., 395, 2010
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3BWA
 | | Crystal Structure of HLA B*3508 in complex with a HCMV 8-mer peptide from the pp65 protein | | 分子名称: | Beta-2-microglobulin, FPT peptide from 65 kDa lower matrix phosphoprotein, HLA class I histocompatibility antigen, ... | | 著者 | Wynn, K.K, Marland, Z, Cooper, L, Silins, S.L, Gras, S, Archbold, J.K, Tynan, F.E, Miles, J.J, McCluskey, J, Burrows, S.R, Rossjohn, J, Khanna, R. | | 登録日 | 2008-01-08 | | 公開日 | 2008-04-22 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Impact of clonal competition for peptide-MHC complexes on the CD8+ T-cell repertoire selection in a persistent viral infection
Blood, 111, 2008
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2UZJ
 | | Crystal structure of the mature streptococcal cysteine protease, mSpeB | | 分子名称: | N-[N-[1-HYDROXYCARBOXYETHYL-CARBONYL]LEUCYLAMINO-BUTYL]-GUANIDINE, STREPTOPAIN | | 著者 | Olsen, J.G, Dagil, R, Niclasen, L.M, Soerensen, O.E, Kragelund, B.B. | | 登録日 | 2008-09-16 | | 公開日 | 2009-09-08 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Structure of the Mature Streptococcal Cysteine Protease Exotoxin Mspeb in its Active Dimeric Form.
J.Mol.Biol., 393, 2009
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2KGI
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3HRZ
 | | Cobra Venom Factor (CVF) in complex with human factor B | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cobra venom factor, ... | | 著者 | Janssen, B.J.C, Gomes, L, Koning, R.I, Svergun, D.I, Koster, A.J, Fritzinger, D.C, Vogel, C.-W, Gros, P. | | 登録日 | 2009-06-10 | | 公開日 | 2009-07-07 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Insights into complement convertase formation based on the structure of the factor B-cobra venom factor complex
Embo J., 28, 2009
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2KRR
 | | Solution structure of the RBD1,2 domains from human nucleolin | | 分子名称: | Nucleolin | | 著者 | Arumugam, N, Miller, C, Maliekal, J, Bates, P.J, Trent, J.O, Lane, A.N. | | 登録日 | 2009-12-22 | | 公開日 | 2010-05-05 | | 最終更新日 | 2024-05-08 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the RBD1,2 domains from human nucleolin.
J.Biomol.Nmr, 47, 2010
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3C27
 | | Cyanofluorophenylacetamides as Orally Efficacious Thrombin Inhibitors | | 分子名称: | Hirudin-3A, N-[2-(carbamimidamidooxy)ethyl]-2-{6-cyano-3-[(2,2-difluoro-2-pyridin-2-ylethyl)amino]-2-fluorophenyl}acetamide, Thrombin heavy chain, ... | | 著者 | Spurlino, J.C, McMillan, M, Lewandowski, F, Milligan, C. | | 登録日 | 2008-01-24 | | 公開日 | 2009-02-17 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.182 Å) | | 主引用文献 | Cyanofluorophenylacetamides as Orally Efficacious Thrombin Inhibitors
To be Published
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3BU6
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3BUG
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2KPW
 | | NMR solution structure of Lamin-B1 protein from Homo sapiens: Northeast Structural Genomics Consortium MEGA target, HR5546A (439-549) | | 分子名称: | Lamin-B1 | | 著者 | Swapna, G.V.T, Ciccosanti, C.L, Belote, R, Hamilton, K, Acton, T, Huang, Y, Xiao, R, Everett, J, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2009-10-21 | | 公開日 | 2009-11-10 | | 最終更新日 | 2024-05-08 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR solution structure of Lamin-B1 protein from Homo sapiens: Northeast Structural Genomics Consortium target, HR5546A (439-549)
To be Published
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2KT1
 | | Solution NMR Structure of the SH3 Domain from the p85beta subunit of Phosphatidylinositol 3-kinase from H.sapiens, Northeast Structural Genomics Consortium Target HR5531E | | 分子名称: | Phosphatidylinositol 3-kinase regulatory subunit beta | | 著者 | Aramini, J.M, Ma, L, Schauder, C, Everett, J.K, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2010-01-15 | | 公開日 | 2010-01-26 | | 最終更新日 | 2024-05-08 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution NMR Structure of the SH3 Domain from the p85beta subunit of Phosphatidylinositol 3-kinase from H.sapiens, Northeast Structural Genomics Consortium Target HR5531E
To be Published
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2K6T
 | | Solution structure of the relaxin-like factor | | 分子名称: | Insulin-like 3 A chain, Insulin-like 3 B chain | | 著者 | Bullesbach, E.E, Hass, M.A.S, Jensen, M.R, Hansen, D.F, Kristensen, S.M, Schwabe, C, Led, J.J. | | 登録日 | 2008-07-23 | | 公開日 | 2008-12-16 | | 最終更新日 | 2022-03-16 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of a conformationally restricted fully active derivative of the human relaxin-like factor
Biochemistry, 47, 2008
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2K7P
 | | Filamin A Ig-like domains 16-17 | | 分子名称: | Filamin-A | | 著者 | Heikkinen, O.K, Kilpelainen, I, Koskela, H, Permi, P, Heikkinen, S, Ylanne, J. | | 登録日 | 2008-08-19 | | 公開日 | 2009-07-07 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Atomic structures of two novel immunoglobulin-like domain pairs in the actin cross-linking protein filamin
J.Biol.Chem., 284, 2009
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3HLC
 | | Simvastatin Synthase (LovD) from Aspergillus terreus, S5 mutant, unliganded | | 分子名称: | GLYCEROL, TETRAETHYLENE GLYCOL, Transesterase | | 著者 | Sawaya, M.R, Yeates, T.O, Laidman, J, Pashkov, I, Gao, X, Tang, Y. | | 登録日 | 2009-05-27 | | 公開日 | 2009-10-27 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Directed evolution and structural characterization of a simvastatin synthase
Chem.Biol., 16, 2009
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3HLD
 | | Simvastatin Synthase (LovD), from Aspergillus terreus, S5 mutant complex with monacolin J acid | | 分子名称: | (3R,5R)-3,5-dihydroxy-7-[(1S,2S,6R,8S,8aR)-8-hydroxy-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]heptanoic acid, FORMIC ACID, Transesterase | | 著者 | Sawaya, M.R, Yeates, T.O, Pashkov, I, Gao, X, Tang, Y. | | 登録日 | 2009-05-27 | | 公開日 | 2009-10-27 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Directed evolution and structural characterization of a simvastatin synthase
Chem.Biol., 16, 2009
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3HLG
 | | Simvastatin Synthase (LovD), from Aspergillus terreus, S5 mutant, S76A mutant, complex with lovastatin | | 分子名称: | (3R,5R)-7-((1R,2R,6S,8R,8AS)-2,6-DIMETHYL-8-{[(2R)-2-METHYLBUTANOYL]OXY}-1,2,6,7,8,8A-HEXAHYDRONAPHTHALEN-1-YL)-3,5-DIHYDROXYHEPTANOIC ACID, Transesterase | | 著者 | Sawaya, M.R, Yeates, T.O, Pashkov, I, Gao, X, Tang, Y. | | 登録日 | 2009-05-27 | | 公開日 | 2009-10-27 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | Directed evolution and structural characterization of a simvastatin synthase
Chem.Biol., 16, 2009
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2KB8
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3HLE
 | | Simvastatin Synthase (LovD), from Aspergillus terreus, S5 mutant, S76A mutant, complex with monacolin J acid | | 分子名称: | (3R,5R)-3,5-dihydroxy-7-[(1S,2S,6R,8S,8aR)-8-hydroxy-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]heptanoic acid, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Transesterase | | 著者 | Sawaya, M.R, Yeates, T.O, Pashkov, I, Gao, X, Tang, Y. | | 登録日 | 2009-05-27 | | 公開日 | 2009-10-27 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | | 主引用文献 | Directed evolution and structural characterization of a simvastatin synthase
Chem.Biol., 16, 2009
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3HLF
 | | Simvastatin Synthase (LovD), from Aspergillus terreus, S5 mutant, S76A mutant, complex with simvastatin | | 分子名称: | Simvastatin acid, Transesterase | | 著者 | Sawaya, M.R, Yeates, T.O, Pashkov, I, Gao, X, Tang, Y. | | 登録日 | 2009-05-27 | | 公開日 | 2009-10-27 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Directed evolution and structural characterization of a simvastatin synthase
Chem.Biol., 16, 2009
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2KDD
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2KBO
 | | Structure, interaction, and real-time monitoring of the enzymatic reaction of wild type APOBEC3G | | 分子名称: | DNA dC->dU-editing enzyme APOBEC-3G, ZINC ION | | 著者 | Furukawa, A, Nagata, T, Matsugami, A, Habu, Y, Sugiyama, R, Hayashi, F, Kobayashi, N, Yokoyama, S, Takaku, H, Katahira, M. | | 登録日 | 2008-12-04 | | 公開日 | 2009-02-03 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure, interaction and real-time monitoring of the enzymatic reaction of wild-type APOBEC3G
Embo J., 28, 2009
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2KBI
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2KBW
 | | Solution Structure of human Mcl-1 complexed with human Bid_BH3 peptide | | 分子名称: | BH3-interacting domain death agonist, Induced myeloid leukemia cell differentiation protein Mcl-1 | | 著者 | Liu, Q, Moldoveanu, T, Sprules, T, Matta-Camacho, E, Mansur-Azzam, N, Gehring, K. | | 登録日 | 2008-12-09 | | 公開日 | 2009-12-15 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Apoptotic regulation by MCL-1 through heterodimerization.
J.Biol.Chem., 285, 2010
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2VHS
 | | Cathsilicatein, a chimera | | 分子名称: | CATHSILICATEIN, SULFATE ION | | 著者 | Fairhead, M, Kowatz, T, McMahon, S.A, Carter, L.G, Oke, M, Johnson, K.A, Liu, H, Naismith, J.H, Wal, C.F.V.D. | | 登録日 | 2007-11-24 | | 公開日 | 2008-03-11 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Crystal Structure and Silica Condensing Activities of Silicatein Alpha-Cathepsin L Chimeras.
Chem. Commun., 2008
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3C7X
 | | Hemopexin-like domain of matrix metalloproteinase 14 | | 分子名称: | CHLORIDE ION, Matrix metalloproteinase-14, SODIUM ION | | 著者 | Tochowicz, A, Itoh, Y, Maskos, K, Bode, W, Goettig, P. | | 登録日 | 2008-02-08 | | 公開日 | 2009-02-10 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | The dimer interface of the membrane type 1 matrix metalloproteinase hemopexin domain: crystal structure and biological functions
J.Biol.Chem., 286, 2011
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