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3BWA

Crystal Structure of HLA B*3508 in complex with a HCMV 8-mer peptide from the pp65 protein

Summary for 3BWA
Entry DOI10.2210/pdb3bwa/pdb
Related3BW9
DescriptorHLA class I histocompatibility antigen, B-35 alpha chain, Beta-2-microglobulin, FPT peptide from 65 kDa lower matrix phosphoprotein, ... (4 entities in total)
Functional Keywordshla b*3508, hcmv, pp65, immunology, glycoprotein, host-virus interaction, immune response, membrane, mhc i, polymorphism, transmembrane, ubl conjugation, disease mutation, glycation, immunoglobulin domain, pyrrolidone carboxylic acid, secreted, phosphoprotein, tegument protein, viral matrix protein, virion, immune system
Biological sourceHomo sapiens (human)
More
Cellular locationMembrane; Single-pass type I membrane protein: P30685
Secreted . Note=(Microbial infection) In the presence of M: P61769
Virion tegument : P06725
Total number of polymer chains3
Total formula weight44754.68
Authors
Wynn, K.K.,Marland, Z.,Cooper, L.,Silins, S.L.,Gras, S.,Archbold, J.K.,Tynan, F.E.,Miles, J.J.,McCluskey, J.,Burrows, S.R.,Rossjohn, J.,Khanna, R. (deposition date: 2008-01-08, release date: 2008-04-22, Last modification date: 2023-11-01)
Primary citationWynn, K.K.,Fulton, Z.,Cooper, L.,Silins, S.L.,Gras, S.,Archbold, J.K.,Tynan, F.E.,Miles, J.J.,McCluskey, J.,Burrows, S.R.,Rossjohn, J.,Khanna, R.
Impact of clonal competition for peptide-MHC complexes on the CD8+ T-cell repertoire selection in a persistent viral infection
Blood, 111:4283-4292, 2008
Cited by
PubMed: 18270323
DOI: 10.1182/blood-2007-11-122622
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.3 Å)
Structure validation

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