2KGI
Solution structure of JARID1A C-terminal PHD finger in complex with H3(1-9)K4me3
Summary for 2KGI
| Entry DOI | 10.2210/pdb2kgi/pdb |
| NMR Information | BMRB: 16210 |
| Descriptor | Histone demethylase JARID1A, H3(1-9)K4me3, ZINC ION (3 entities in total) |
| Functional Keywords | phd finger, jarid1a, histone modification, leukemia, alternative splicing, chromatin regulator, developmental protein, dioxygenase, iron, metal-binding, nucleus, oxidoreductase, phosphoprotein, polymorphism, transcription, transcription regulation, zinc, zinc-finger, metal binding protein |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 2 |
| Total formula weight | 7038.64 |
| Authors | Song, J.,Wang, Z.,Patel, D.J. (deposition date: 2009-03-12, release date: 2009-05-05, Last modification date: 2020-02-26) |
| Primary citation | Wang, G.G.,Song, J.,Wang, Z.,Dormann, H.L.,Casadio, F.,Li, H.,Luo, J.L.,Patel, D.J.,Allis, C.D. Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger. Nature, 459:847-851, 2009 Cited by PubMed: 19430464DOI: 10.1038/nature08036 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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