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2VDM
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Re-refinement of Integrin AlphaIIbBeta3 Headpiece Bound to Antagonist Tirofiban
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GLYCEROL, ...
著者Springer, T.A, Zhu, J, Xiao, T.
登録日2007-10-10
公開日2008-09-02
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural Basis for Distinctive Recognition of Fibrinogen Gammac Peptide by the Platelet Integrin Alphaiibbeta3.
J.Cell Biol., 182, 2008
2VDL
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BU of 2vdl by Molmil
Re-refinement of Integrin AlphaIIbBeta3 Headpiece
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CACODYLATE ION, CALCIUM ION, ...
著者Springer, T.A, Zhu, J, Xiao, T.
登録日2007-10-10
公開日2008-09-02
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structural Basis for Distinctive Recognition of Fibrinogen Gammac Peptide by the Platelet Integrin Alphaiibbeta3.
J.Cell Biol., 182, 2008
4DK3
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BU of 4dk3 by Molmil
Structure of Editosome protein
分子名称: RNA-editing complex protein MP81, single domain antibody VHH
著者Park, Y.-J, Hol, W.
登録日2012-02-03
公開日2012-07-04
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.76 Å)
主引用文献The structure of the C-terminal domain of the largest editosome interaction protein and its role in promoting RNA binding by RNA-editing ligase L2.
Nucleic Acids Res., 40, 2012
2VC2
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BU of 2vc2 by Molmil
Re-refinement of Integrin AlphaIIbBeta3 Headpiece Bound to Antagonist L-739758
分子名称: 2-(S)-[N-(3-PYRIDYLSULFONYL)AMINO]-3-[[2-CARBONYL-5-[2-(PIPERIDIN-4-YL)ETHYL]-THIENO[2,3-B]THIOPHENEYL]AMINO]-PROPIONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Springer, T.A, Zhu, J, Xiao, T.
登録日2007-09-18
公開日2008-09-02
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural Basis for Distinctive Recognition of Fibrinogen Gammac Peptide by the Platelet Integrin Alphaiibbeta3.
J.Cell Biol., 182, 2008
5VK6
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BU of 5vk6 by Molmil
Open conformation of KcsA non-inactivating E71A mutant
分子名称: (1S)-2-HYDROXY-1-[(NONANOYLOXY)METHYL]ETHYL MYRISTATE, Antibody Heavy Chain, Antibody Light Chain, ...
著者Cuello, L.G, Perozo, E.
登録日2017-04-21
公開日2017-12-06
最終更新日2020-01-01
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献The gating cycle of a K+ channel at atomic resolution.
Elife, 6, 2017
5VKH
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BU of 5vkh by Molmil
Closed conformation of KcsA Y82A-F103A mutant
分子名称: (1S)-2-HYDROXY-1-[(NONANOYLOXY)METHYL]ETHYL MYRISTATE, Antibody Heavy Chain, Antibody Light Chain, ...
著者Cuello, L.G, Perozo, E, Cortes, D.M.
登録日2017-04-21
公開日2017-12-06
最終更新日2020-01-01
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献The gating cycle of a K+ channel at atomic resolution.
Elife, 6, 2017
4WFH
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BU of 4wfh by Molmil
Human TRAAK K+ channel in a Tl+ bound nonconductive conformation
分子名称: ANTI-TRAAK ANTIBODY 13E9 FAB FRAGMENT HEAVY CHAIN, ANTI-TRAAK ANTIBODY 13E9 FAB FRAGMENT LIGHT CHAIN, CALCIUM ION, ...
著者Brohawn, S.G, MacKinnon, R.
登録日2014-09-15
公開日2014-12-03
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.01 Å)
主引用文献Physical mechanism for gating and mechanosensitivity of the human TRAAK K+ channel.
Nature, 516, 2014
4WFG
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BU of 4wfg by Molmil
Human TRAAK K+ channel in a Tl+ bound conductive conformation
分子名称: ANTI-TRAAK ANTIBODY 13E9 FAB FRAGMENT HEAVY CHAIN, ANTI-TRAAK ANTIBODY 13E9 FAB FRAGMENT LIGHT CHAIN, CALCIUM ION, ...
著者Brohawn, S.G, MacKinnon, R.
登録日2014-09-15
公開日2014-12-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Physical mechanism for gating and mechanosensitivity of the human TRAAK K+ channel.
Nature, 516, 2014
4WFE
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BU of 4wfe by Molmil
Human TRAAK K+ channel in a K+ bound conductive conformation
分子名称: ANTI-TRAAK ANTIBODY 13E9 FAB FRAGMENT HEAVY CHAIN, ANTI-TRAAK ANTIBODY 13E9 FAB FRAGMENT LIGHT CHAIN, CALCIUM ION, ...
著者Brohawn, S.G, MacKinnon, R.
登録日2014-09-15
公開日2014-12-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Physical mechanism for gating and mechanosensitivity of the human TRAAK K+ channel.
Nature, 516, 2014
4WFF
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BU of 4wff by Molmil
Human TRAAK K+ channel in a K+ bound nonconductive conformation
分子名称: ANTI-TRAAK ANTIBODY 13E9 FAB FRAGMENT HEAVY CHAIN, ANTI-TRAAK ANTIBODY 13E9 FAB FRAGMENT LIGHT CHAIN, CALCIUM ION, ...
著者Brohawn, S.G, MacKinnon, R.
登録日2014-09-15
公開日2014-12-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Physical mechanism for gating and mechanosensitivity of the human TRAAK K+ channel.
Nature, 516, 2014
1ZWI
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BU of 1zwi by Molmil
Structure of mutant KcsA potassium channel
分子名称: DIACYL GLYCEROL, NONAN-1-OL, POTASSIUM ION, ...
著者Cordero-Morales, J.F, Cuello, L.G, Zhao, Y, Jogini, V, Cortes, D.M, Roux, B, Perozo, E.
登録日2005-06-03
公開日2006-03-07
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Molecular determinants of gating at the potassium-channel selectivity filter.
Nat.Struct.Mol.Biol., 13, 2006
4XNU
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BU of 4xnu by Molmil
X-ray structure of Drosophila dopamine transporter in complex with nisoxetine
分子名称: CHLORIDE ION, CHOLESTEROL, Integral membrane protein-dopamine transporter, ...
著者Aravind, P, Wang, K, Gouaux, E.
登録日2015-01-16
公開日2015-05-13
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.98 Å)
主引用文献X-ray structures of Drosophila dopamine transporter in complex with nisoxetine and reboxetine.
Nat.Struct.Mol.Biol., 22, 2015
4XP1
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BU of 4xp1 by Molmil
X-ray structure of Drosophila dopamine transporter bound to neurotransmitter dopamine
分子名称: 1,2-ETHANEDIOL, 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Gouaux, E, Penmatsa, A, Wang, K.
登録日2015-01-16
公開日2015-05-06
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.89 Å)
主引用文献Neurotransmitter and psychostimulant recognition by the dopamine transporter.
Nature, 521, 2015
4XP5
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BU of 4xp5 by Molmil
X-ray structure of Drosophila dopamine transporter bound to cocaine analogue-RTI55
分子名称: 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, Antibody fragment heavy chain-protein, 9D5-heavy chain, ...
著者Gouaux, E, Penmatsa, A, Wang, K.
登録日2015-01-16
公開日2015-05-06
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Neurotransmitter and psychostimulant recognition by the dopamine transporter.
Nature, 521, 2015
4XPT
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BU of 4xpt by Molmil
X-ray structure of Drosophila dopamine transporter with subsiteB mutations D121G/S426M and EL2 deletion of 162-201 in complex with substrate analogue 3,4 dichlorophen ethylamine
分子名称: 2-(3,4-dichlorophenyl)ethanamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
著者Aravind, P, Wang, K, Gouaux, E.
登録日2015-01-17
公開日2015-05-06
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.36 Å)
主引用文献Neurotransmitter and psychostimulant recognition by the dopamine transporter.
Nature, 521, 2015
4XNX
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BU of 4xnx by Molmil
X-ray structure of Drosophila dopamine transporter in complex with reboxetine
分子名称: (2R)-2-[(R)-(2-ethoxyphenoxy)(phenyl)methyl]morpholine, Antibody fragment heavy chain, CHLORIDE ION, ...
著者Aravind, P, Wang, K, Gouaux, E.
登録日2015-01-16
公開日2015-05-13
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献X-ray structures of Drosophila dopamine transporter in complex with nisoxetine and reboxetine.
Nat.Struct.Mol.Biol., 22, 2015
4XP6
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BU of 4xp6 by Molmil
X-ray structure of Drosophila dopamine transporter bound to psychostimulant methamphetamine
分子名称: (2S)-N-methyl-1-phenylpropan-2-amine, 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody fragment heavy chain-protein, ...
著者Aravind, P, Wang, K, Gouaux, E.
登録日2015-01-16
公開日2015-05-13
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Neurotransmitter and psychostimulant recognition by the dopamine transporter.
Nature, 521, 2015
4XP9
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BU of 4xp9 by Molmil
X-ray structure of Drosophila dopamine transporter bound to psychostimulant D-amphetamine
分子名称: (2S)-1-phenylpropan-2-amine, 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Aravind, P, Wang, K, Gouaux, E.
登録日2015-01-16
公開日2015-05-06
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Neurotransmitter and psychostimulant recognition by the dopamine transporter.
Nature, 521, 2015
2ATY
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BU of 2aty by Molmil
Complement receptor chimaeric conjugate CR2-Ig
分子名称: Complement receptor chimeric conjugate CR2-Ig
著者Gilbert, H.E, Aslam, M, Guthridge, J.M, Holers, V.M, Perkins, S.J.
登録日2005-08-26
公開日2006-01-31
最終更新日2024-02-14
実験手法SOLUTION SCATTERING
主引用文献Extended Flexible Linker Structures in the Complement Chimaeric Conjugate CR2-Ig by Scattering, Analytical Ultracentrifugation and Constrained Modelling: Implications for Function and Therapy.
J.Mol.Biol., 356, 2006
4XPA
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BU of 4xpa by Molmil
X-ray structure of Drosophila dopamine transporter bound to 3,4dichlorophenethylamine
分子名称: 2-(3,4-dichlorophenyl)ethanamine, Antibody fragment heavy chain-protein, 9D5-heavy chain, ...
著者Aravind, P, Wang, K, Gouaux, E.
登録日2015-01-16
公開日2015-05-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Neurotransmitter and psychostimulant recognition by the dopamine transporter.
Nature, 521, 2015
1DQD
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BU of 1dqd by Molmil
CRYSTAL STRUCTURE OF FAB HGR-2 F6, A COMPETITIVE ANTAGONIST OF THE GLUCAGON RECEPTOR
分子名称: FAB HGR-2 F6
著者Wright, L.M, Brzozowski, A.M, Hubbard, R.E, Pike, A.C.W, Roberts, S.M, Skovgaard, R.N, Svendsen, I, Vissing, H, Bywater, R.P.
登録日2000-01-04
公開日2000-05-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure of Fab hGR-2 F6, a competitive antagonist of the glucagon receptor.
Acta Crystallogr.,Sect.D, 56, 2000
5VXR
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BU of 5vxr by Molmil
The antigen-binding fragment of MAb24 in complex with a peptide from Hepatitis C Virus E2 epitope I (412-423)
分子名称: GLYCEROL, MAb24 Variable Heavy Chain,MAb24 Variable Heavy Chain, MAb24 Variable Light Chain,MAb24 Variable Light Chain, ...
著者Hardy, J.M, Gu, J, Boo, I, Drummer, H.E, Coulibaly, F.J.
登録日2017-05-24
公開日2018-02-21
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Escape of Hepatitis C Virus from Epitope I Neutralization Increases Sensitivity of Other Neutralization Epitopes.
J. Virol., 92, 2018
3KLH
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BU of 3klh by Molmil
Crystal structure of AZT-Resistant HIV-1 Reverse Transcriptase crosslinked to post-translocation AZTMP-Terminated DNA (COMPLEX P)
分子名称: DNA (5'-D(*AP*CP*AP*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*(MRG)P*CP*GP*CP*CP*(ATM))-3'), DNA (5'-D(*AP*T*GP*CP*TP*AP*GP*GP*CP*GP*CP*CP*CP*GP*AP*AP*CP*AP*GP*GP*GP*AP*CP*TP*GP*TP*G)-3'), MAGNESIUM ION, ...
著者Tu, X, Sarafianos, S.G, Arnold, E.
登録日2009-11-07
公開日2010-09-22
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural basis of HIV-1 resistance to AZT by excision.
Nat.Struct.Mol.Biol., 17, 2010
6B3S
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BU of 6b3s by Molmil
Crystal structure of the Fab fragment of necitumumab (Fab11F8) in complex with domain III from a cetuximab resistant variant of EGFR (sEGFRd3-S468R)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Epidermal growth factor receptor, ...
著者Ferguson, K.M, Bagchi, A.
登録日2017-09-23
公開日2017-12-06
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Molecular Basis for Necitumumab Inhibition of EGFR Variants Associated with Acquired Cetuximab Resistance.
Mol. Cancer Ther., 17, 2018
3NID
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BU of 3nid by Molmil
The Closed Headpiece of Integrin alphaIIB beta3 and its Complex with an alpahIIB beta3 -Specific Antagonist That Does Not Induce Opening
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Zhu, J.H, Zhu, J.Q, Springer, T.A.
登録日2010-06-15
公開日2010-12-22
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Closed headpiece of integrin {alpha}IIb{beta}3 and its complex with an {alpha}IIb{beta}3-specific antagonist that does not induce opening.
Blood, 116, 2010

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