4WFH

Human TRAAK K+ channel in a Tl+ bound nonconductive conformation

Summary for 4WFH

Entry DOI	10.2210/pdb4wfh/pdb
Related	4WFE 4WFF 4WFG
Descriptor	Potassium channel subfamily K member 4, ANTI-TRAAK ANTIBODY 13E9 FAB FRAGMENT LIGHT CHAIN, ANTI-TRAAK ANTIBODY 13E9 FAB FRAGMENT HEAVY CHAIN, ... (7 entities in total)
Functional Keywords	mechanosensitive ion channel, two-pore domain potassium ion channel, membrane protein, metal transport
Biological source	Homo sapiens (Human) More
Cellular location	Membrane ; Multi-pass membrane protein : Q9NYG8
Total number of polymer chains	6
Total formula weight	159858.07
Authors	Brohawn, S.G.,MacKinnon, R. (deposition date: 2014-09-15, release date: 2014-12-03, Last modification date: 2023-12-27)
Primary citation	Brohawn, S.G.,Campbell, E.B.,MacKinnon, R. Physical mechanism for gating and mechanosensitivity of the human TRAAK K+ channel. Nature, 516:126-130, 2014 Cited by PubMed: 25471887 DOI: 10.1038/nature14013 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.01 Å)

Structure validation