4WFH
Human TRAAK K+ channel in a Tl+ bound nonconductive conformation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Potassium channel subfamily K member 4 | polymer | 299 | 32569.7 | 2 | UniProt (Q9NYG8) Pfam (PF07885) | Homo sapiens (Human) | TWIK-related arachidonic acid-stimulated potassium channel protein,TRAAK,Two pore potassium channel KT4.1,Two pore K(+) channel KT4.1 |
| 2 | C, E (D, F) | ANTI-TRAAK ANTIBODY 13E9 FAB FRAGMENT LIGHT CHAIN | polymer | 211 | 23038.4 | 2 | Mus musculus (mouse) | ||
| 3 | D, F (E, G) | ANTI-TRAAK ANTIBODY 13E9 FAB FRAGMENT HEAVY CHAIN | polymer | 217 | 23474.4 | 2 | Mus musculus (mouse) | ||
| 4 | G, H, I, J, M... (A, B) | THALLIUM (I) ION | non-polymer | 204.4 | 7 | Chemie (TL) | |||
| 5 | K, L, Q (A, G) | CALCIUM ION | non-polymer | 40.1 | 3 | Chemie (CA) | |||
| 6 | P (B) | DECANE | non-polymer | 142.3 | 1 | Chemie (D10) | |||
| 7 | R, S, T, U, V... (A, B, D, E, F...) | water | water | 18.0 | 184 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 290 (UniProt: Q9NYG8)
| PDB | External Database | Details |
|---|---|---|
| Gln 104 | Asn 104 | engineered mutation |
| Gln 108 | Asn 108 | engineered mutation |
| Ser 291 | - | expression tag |
| Asn 292 | - | expression tag |
| Ser 293 | - | expression tag |
| Leu 294 | - | expression tag |
| Glu 295 | - | expression tag |
| Val 296 | - | expression tag |
| Leu 297 | - | expression tag |
| Phe 298 | - | expression tag |
| Gln 299 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 158164.9 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1693.2 | |
| All* | Total formula weight | 159858.1 |
