1DQD

CRYSTAL STRUCTURE OF FAB HGR-2 F6, A COMPETITIVE ANTAGONIST OF THE GLUCAGON RECEPTOR

Summary for 1DQD

• Entry DOI: 10.2210/pdb1dqd/pdb
• Descriptor: FAB HGR-2 F6 (3 entities in total)
• Functional Keywords: glucagon receptor, monoclonal antibody, fab, receptor antagonist, typical immunoglobulin fold, light chain, heavy chain, antigen binding site, complementarity-determining regions, immune system
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 2
• Total formula weight: 47846.04

Authors

Wright, L.M.,Brzozowski, A.M.,Hubbard, R.E.,Pike, A.C.W.,Roberts, S.M.,Skovgaard, R.N.,Svendsen, I.,Vissing, H.,Bywater, R.P. (deposition date: 2000-01-04, release date: 2000-05-10, Last modification date: 2011-07-13)

• Primary citation: Wright, L.M.,Brzozowski, A.M.,Hubbard, R.E.,Pike, A.C.,Roberts, S.M.,Skovgaard, R.N.,Svendsen, I.,Vissing, H.,Bywater, R.P.; Structure of Fab hGR-2 F6, a competitive antagonist of the glucagon receptor.; Acta Crystallogr.,Sect.D, 56:573-580, 2000; PubMed: 10771426; DOI: 10.1107/S090744490000233X

Experimental method

X-RAY DIFFRACTION (2.1 Å)