X-ray structure of Drosophila dopamine transporter bound to neurotransmitter dopamine

Summary for 4XP1

Related4XNX 4XP4 4XP5 4XP6 4XP9 4XPA 4XPB 4XPF 4XPG 4XPH 4XPT
DescriptorDopamine transporter, isoform B, Antibody fragment light chain, antibody fragment heavy chain, ... (13 entities in total)
Functional Keywordsintegral membrane protein, membrane protein-transport protein complex, membrane protein/transport protein
Biological sourceDrosophila melanogaster (Fruit fly)
Total number of polymer chains3
Total molecular weight109207.51
Gouaux, E.,Penmatsa, A.,Wang, K. (deposition date: 2015-01-16, release date: 2015-05-06, Last modification date: 2017-11-22)
Primary citation
Wang, K.H.,Penmatsa, A.,Gouaux, E.
Neurotransmitter and psychostimulant recognition by the dopamine transporter.
Nature, 521:322-327, 2015
PubMed: 25970245 (PDB entries with the same primary citation)
DOI: 10.1038/nature14431
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.2581805.1%1.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution