4XP1

X-ray structure of Drosophila dopamine transporter bound to neurotransmitter dopamine

Summary for 4XP1

Related4XNX 4XP4 4XP5 4XP6 4XP9 4XPA 4XPB 4XPF 4XPG 4XPH 4XPT
Related PRD IDPRD_900001
DescriptorDopamine transporter, isoform B, Antibody fragment light chain, antibody fragment heavy chain, ... (13 entities in total)
Functional Keywordsintegral membrane protein, membrane protein-transport protein complex, membrane protein/transport protein
Biological sourceDrosophila melanogaster (Fruit fly)
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Total number of polymer chains3
Total molecular weight109207.51
Authors
Gouaux, E.,Penmatsa, A.,Wang, K. (deposition date: 2015-01-16, release date: 2015-05-06, Last modification date: 2020-07-29)
Primary citation
Wang, K.H.,Penmatsa, A.,Gouaux, E.
Neurotransmitter and psychostimulant recognition by the dopamine transporter.
Nature, 521:322-327, 2015
PubMed: 25970245 (PDB entries with the same primary citation)
DOI: 10.1038/nature14431
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.89 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.258180 5.1% 1.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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168889
PDB entries from 2020-09-16