4XP6
X-ray structure of Drosophila dopamine transporter bound to psychostimulant methamphetamine
Summary for 4XP6
| Entry DOI | 10.2210/pdb4xp6/pdb |
| Related | 4XNX 4XP1 4XP4 4XP5 4XP9 4XPA 4XPB 4XPF 4XPG 4XPH 4XPT |
| Related PRD ID | PRD_900001 |
| Descriptor | Transporter, CHOLESTEROL HEMISUCCINATE, Antibody fragment heavy chain-protein, 9D5-heavy chain, ... (11 entities in total) |
| Functional Keywords | integral membrane protein, all-alpha helical antidepressant complex, tranport protein-inhibitor complex, tranport protein/inhibitor |
| Biological source | Drosophila melanogaster (Fruit fly) More |
| Total number of polymer chains | 3 |
| Total formula weight | 108356.74 |
| Authors | Aravind, P.,Wang, K.,Gouaux, E. (deposition date: 2015-01-16, release date: 2015-05-13, Last modification date: 2023-09-27) |
| Primary citation | Wang, K.H.,Penmatsa, A.,Gouaux, E. Neurotransmitter and psychostimulant recognition by the dopamine transporter. Nature, 521:322-327, 2015 Cited by PubMed: 25970245DOI: 10.1038/nature14431 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.1 Å) |
Structure validation
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