5VXR

The antigen-binding fragment of MAb24 in complex with a peptide from Hepatitis C Virus E2 epitope I (412-423)

Summary for 5VXR

Entry DOI	10.2210/pdb5vxr/pdb
Descriptor	MAb24 Variable Heavy Chain,MAb24 Variable Heavy Chain, MAb24 Variable Light Chain,MAb24 Variable Light Chain, Virus Envelope Protein 2, ... (5 entities in total)
Functional Keywords	antibody, immune system
Biological source	Mus musculus (Mouse) More
Total number of polymer chains	3
Total formula weight	49463.46
Authors	Hardy, J.M.,Gu, J.,Boo, I.,Drummer, H.E.,Coulibaly, F.J. (deposition date: 2017-05-24, release date: 2018-02-21, Last modification date: 2023-10-04)
Primary citation	Gu, J.,Hardy, J.,Boo, I.,Vietheer, P.,McCaffrey, K.,Alhammad, Y.,Chopra, A.,Gaudieri, S.,Poumbourios, P.,Coulibaly, F.,Drummer, H.E. Escape of Hepatitis C Virus from Epitope I Neutralization Increases Sensitivity of Other Neutralization Epitopes. J. Virol., 92:-, 2018 Cited by PubMed: 29467319 DOI: 10.1128/JVI.02066-17 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.4 Å)

Structure validation