7PA9
 
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8B50
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7T17
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7TDM
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7TDN
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5UTY
 | | Crystal Structure of a Stabilized DS-SOSIP.mut4 BG505 gp140 HIV-1 Env Trimer, Containing Mutations I201C-P433C (DS), L154M, N300M, N302M, T320L in Complex with Human Antibodies PGT122 and 35O22 at 4.1 Angstrom | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22 Fab heavy chain, ... | | 著者 | Xu, K, Chuang, G.-Y, Pancera, M, Kwong, P.D. | | 登録日 | 2017-02-15 | | 公開日 | 2017-03-29 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (3.412 Å) | | 主引用文献 | Structure-Based Design of a Soluble Prefusion-Closed HIV-1 Env Trimer with Reduced CD4 Affinity and Improved Immunogenicity.
J. Virol., 91, 2017
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8PKC
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8PIH
 | | Structure of Api m1 in complex with two nanobodies | | 分子名称: | CHLORIDE ION, Phospholipase A2, nanobdoy AM1-1, ... | | 著者 | Aagaard, J.B, Gandini, R, Spillner, E, Miehe, M, Andersen, G.R. | | 登録日 | 2023-06-21 | | 公開日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | | 主引用文献 | Nanobody-based IgG formats as blocking antibodies of the major honeybee venom allergen Api m 1
To be published
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4HIJ
 | | Anti-Streptococcus pneumoniae 23F Fab 023.102 with bound L-rhamnose-(1-2)-alpha-D-galactose-(3-O)-phosphate-2-glycerol | | 分子名称: | Fab 023.102 heavy chain, Fab 023.102 light chain, GLYCEROL, ... | | 著者 | Bryson, S, Risnes, L, Damgupta, S, Thomson, C.A, Schrader, J.W, Pai, E.F. | | 登録日 | 2012-10-11 | | 公開日 | 2013-08-28 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structures of Preferred Human IgV Genes-Based Protective Antibodies Identify How Conserved Residues Contact Diverse Antigens and Assign Source of Specificity to CDR3 Loop Variation.
J. Immunol., 196, 2016
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4HII
 | | Anti-Streptococcus pneumoniae 23F Fab 023.102 with bound rhamnose-galactose | | 分子名称: | Fab 023.102 heavy chain, Fab 023.102 light chain, alpha-L-rhamnopyranose-(1-2)-beta-D-galactopyranose | | 著者 | Bryson, S, Risnes, L, Damgupta, S, Thomson, C.A, Schrader, J.W, Pai, E.F. | | 登録日 | 2012-10-11 | | 公開日 | 2013-08-28 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structures of Preferred Human IgV Genes-Based Protective Antibodies Identify How Conserved Residues Contact Diverse Antigens and Assign Source of Specificity to CDR3 Loop Variation.
J. Immunol., 196, 2016
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4HH9
 | | Anti-Human Cytomegalovirus (HCMV) Fab KE5 | | 分子名称: | Fab KE5, heavy chain, light chain | | 著者 | Bryson, S, Risnes, L, Damgupta, S, Thomson, C.A, Pfoh, R, Schrader, J.W, Pai, E.F. | | 登録日 | 2012-10-09 | | 公開日 | 2013-10-23 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structures of Preferred Human IgV Genes-Based Protective Antibodies Identify How Conserved Residues Contact Diverse Antigens and Assign Source of Specificity to CDR3 Loop Variation.
J. Immunol., 196, 2016
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6KX0
 | | Crystal structure of SN-101 mAb non-liganded form | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Fab Fragment-SN-101-Heavy chain, Fab Fragment-SN-101-Light chain | | 著者 | Wakui, H, Tanaka, Y, Kato, K, Ose, T, Matsumoto, I, Min, Y, Tachibana, T, Nishimura, S.-I. | | 登録日 | 2019-09-09 | | 公開日 | 2020-07-29 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.404 Å) | | 主引用文献 | A straightforward approach to antibodies recognising cancer specific glycopeptidic neoepitopes
Chem Sci, 11, 2020
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6KX1
 | | Crystal structure of SN-101 mAb in complex with MUC1 glycopeptide | | 分子名称: | 2-acetamido-2-deoxy-alpha-D-galactopyranose, Fab Fragment-SN-101-Heavy chain, Fab Fragment-SN-101-Light chain, ... | | 著者 | Wakui, H, Tanaka, Y, Kato, K, Ose, T, Matsumoto, I, Min, Y, Tachibana, T, Nishimura, S.-I. | | 登録日 | 2019-09-09 | | 公開日 | 2020-07-29 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.773 Å) | | 主引用文献 | A straightforward approach to antibodies recognising cancer specific glycopeptidic neoepitopes
Chem Sci, 11, 2020
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6OC8
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6O8D
 | | Anti-CD28xCD3 CODV Fab bound to CD28 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Anti-CD28xCD3 CODV Fab Heavy chain, ... | | 著者 | Lord, D.M, Wei, R.R. | | 登録日 | 2019-03-09 | | 公開日 | 2019-11-20 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.547 Å) | | 主引用文献 | Trispecific antibodies enhance the therapeutic efficacy of tumor-directed T cells through T cell receptor co-stimulation
To Be Published
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8SUO
 | | BA.2/AZD1061/AZD3152 structure analysis | | 分子名称: | AZD1061 heavy chain, AZD1061 light chain, AZD3152 heavy chain, ... | | 著者 | Oganesyan, V, van Dyk, N, Dippel, A, Barnes, A, O'Connor, E. | | 登録日 | 2023-05-12 | | 公開日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | X-ray crystal structure of BA.2 RBD bound by two neutralizing antibodies
To Be Published
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8PMX
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8PMW
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8PN0
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8PMZ
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8PMY
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7F7H
 | | SARS-CoV-2 S protein RBD in complex with A8-1 Fab | | 分子名称: | Heavy chain of A8-1 Fab, Light chain of A8-1 Fab, Spike glycoprotein S1 | | 著者 | Dou, Y, Wang, X, Wang, K, Liu, P, Lu, B. | | 登録日 | 2021-06-29 | | 公開日 | 2022-06-15 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.19 Å) | | 主引用文献 | High throughput isolation of potent neutralizing antibodies from convalescent COVID-19 patients.
To Be Published
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7C88
 | | Complex structure of JS003 and PD-L1 | | 分子名称: | JS003 Heavy chain, JS003 Light chain, Programmed cell death 1 ligand 1 | | 著者 | Bi, X, Shi, R, Chai, Y, Qi, J, Yan, J, Tan, S. | | 登録日 | 2020-05-29 | | 公開日 | 2021-04-14 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.997 Å) | | 主引用文献 | Identification of a hotspot on PD-L1 for pH-dependent binding by monoclonal antibodies for tumor therapy.
Signal Transduct Target Ther, 5, 2020
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7EY5
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7EYA
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