6KX1

Crystal structure of SN-101 mAb in complex with MUC1 glycopeptide

Summary for 6KX1

• Entry DOI: 10.2210/pdb6kx1/pdb
• Descriptor: Fab Fragment-SN-101-Heavy chain, Fab Fragment-SN-101-Light chain, Synthetic MUC1 glycopepide, ... (5 entities in total)
• Functional Keywords: antibody, igg1, muc1, glycopeptide, immune system
• Biological source: Mus musculus (Mouse); More
• Total number of polymer chains: 3
• Total formula weight: 53656.21

Authors

Wakui, H.,Tanaka, Y.,Kato, K.,Ose, T.,Matsumoto, I.,Min, Y.,Tachibana, T.,Nishimura, S.-I. (deposition date: 2019-09-09, release date: 2020-07-29, Last modification date: 2023-11-22)

• Primary citation: Wakui, H.,Tanaka, Y.,Ose, T.,Matsumoto, I.,Kato, K.,Min, Y.,Tachibana, T.,Sato, M.,Naruchi, K.,Martin, F.G.,Hinou, H.,Nishimura, S.-I.; A straightforward approach to antibodies recognising cancer specific glycopeptidic neoepitopes; Chem Sci, 11:4999-5006, 2020; DOI: 10.1039/D0SC00317D

Experimental method

X-RAY DIFFRACTION (1.773 Å)