8B50

Crystal structure of a Fab fragment in complex with L-hydroxycoumarylalanine

Summary for 8B50

• Entry DOI: 10.2210/pdb8b50/pdb
• Descriptor: Fab fragment K12F9-22 - heavy chain, Fab fragment K12F9-22 - light chain, (2~{S})-2-azanyl-3-(7-oxidanyl-2-oxidanylidene-chromen-4-yl)propanoic acid, ... (5 entities in total)
• Functional Keywords: antibody, fluorescent side chain, hapten, non-natural amino acid, recombinant fab, umbelliferylalanine, immune system
• Biological source: Mus musculus; More
• Total number of polymer chains: 2
• Total formula weight: 48882.70

Authors

Meining, W.,Eichinger, A.,Skerra, A. (deposition date: 2022-09-21, release date: 2023-10-04, Last modification date: 2026-03-04)

• Primary citation: Rubini, M.,Meining, W.,Eichinger, A.,Mueller, M.,Kramer, K.,Skerra, A.; Preparation and characterization of monoclonal antibodies against a non natural amino acid carrying the 7-hydroxycoumarin side chain; To be published,

Experimental method

X-RAY DIFFRACTION (1.67 Å)