6KX0

Crystal structure of SN-101 mAb non-liganded form

Summary for 6KX0

Entry DOI	10.2210/pdb6kx0/pdb
Descriptor	Fab Fragment-SN-101-Heavy chain, Fab Fragment-SN-101-Light chain, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (4 entities in total)
Functional Keywords	antibody, igg1, muc1, glycopeptide, immune system
Biological source	Mus musculus (Mouse) More
Total number of polymer chains	2
Total formula weight	52224.72
Authors	Wakui, H.,Tanaka, Y.,Kato, K.,Ose, T.,Matsumoto, I.,Min, Y.,Tachibana, T.,Nishimura, S.-I. (deposition date: 2019-09-09, release date: 2020-07-29, Last modification date: 2023-11-22)
Primary citation	Wakui, H.,Tanaka, Y.,Ose, T.,Matsumoto, I.,Kato, K.,Min, Y.,Tachibana, T.,Sato, M.,Naruchi, K.,Martin, F.G.,Hinou, H.,Nishimura, S.-I. A straightforward approach to antibodies recognising cancer specific glycopeptidic neoepitopes Chem Sci, 11:4999-5006, 2020 Cited by DOI: 10.1039/D0SC00317D PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.404 Å)

Structure validation