PDB: 902 件ウェブページステータス検索Chemie searchBIRD

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8F0K	Human Amylin3 Receptor in complex with Gs and Pramlintide analogue peptide San385 分子名称: (2S)-2-{[(1R)-1-hydroxyhexadecyl]oxy}-3-{[(1R)-1-hydroxyoctadecyl]oxy}propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, ... 著者 Cao, J, Sexton, P.M, Wootten, D.L. 登録日 2022-11-03 公開日 2023-08-02 最終更新日 2024-02-14 実験手法 ELECTRON MICROSCOPY (1.9 Å) 主引用文献 Structural insight into selectivity of amylin and calcitonin receptor agonists. Nat.Chem.Biol., 20, 2024
8HDO	Structure of A2BR bound to synthetic agonists BAY 60-6583 分子名称: 2-[6-azanyl-3,5-dicyano-4-[4-(cyclopropylmethoxy)phenyl]pyridin-2-yl]sulfanylethanamide, Adenosine A2b receptor, CHOLESTEROL, ... 著者 Cai, H, Xu, Y, Xu, H.E, Jiang, Y. 登録日 2022-11-05 公開日 2023-01-18 実験手法 ELECTRON MICROSCOPY (2.87 Å) 主引用文献 Structures of adenosine receptor A 2B R bound to endogenous and synthetic agonists. Cell Discov, 8, 2022
8HDP	Structure of A2BR bound to endogenous agonists adenosine 分子名称: ADENOSINE, Adenosine A2b receptor, CHOLESTEROL, ... 著者 Cai, H, Xu, Y, Xu, H.E, Jiang, Y. 登録日 2022-11-05 公開日 2023-01-18 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structures of adenosine receptor A 2B R bound to endogenous and synthetic agonists. Cell Discov, 8, 2022
8F2B	Amylin 3 Receptor in complex with Gs and Pramlintide analogue peptide San45 分子名称: (2S)-2-{[(1R)-1-hydroxyhexadecyl]oxy}-3-{[(1R)-1-hydroxyoctadecyl]oxy}propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, ... 著者 Cao, J, Sexton, P.M, Wootten, D.L, Belousoff, M.J. 登録日 2022-11-07 公開日 2023-08-02 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (2 Å) 主引用文献 Structural insight into selectivity of amylin and calcitonin receptor agonists. Nat.Chem.Biol., 20, 2024
8F2A	Human Amylin3 Receptor in complex with Gs and Pramlintide analogue peptide San385 (Cluster 5 conformation) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Calcitonin receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Cao, J, Sexton, P.M, Wootten, D.L, Radostin, D. 登録日 2022-11-07 公開日 2023-08-02 最終更新日 2024-02-14 実験手法 ELECTRON MICROSCOPY (2.2 Å) 主引用文献 Structural insight into selectivity of amylin and calcitonin receptor agonists. Nat.Chem.Biol., 20, 2024
8F76	Human olfactory receptor OR51E2 bound to propionate in complex with miniGs399 分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... 著者 Billesboelle, C.B, Manglik, A. 登録日 2022-11-18 公開日 2023-03-22 最終更新日 2023-04-05 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural basis of odorant recognition by a human odorant receptor. Nature, 615, 2023
8F7S	Gi bound delta-opioid receptor in complex with deltorphin 分子名称: CHOLESTEROL, Delta-type opioid receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Wang, Y, Zhuang, Y, DiBerto, J.F, Zhou, X.E, Schmitz, G.P, Yuan, Q, Jain, M.K, Liu, W, Melcher, K, Jiang, Y, Roth, B.L, Xu, H.E. 登録日 2022-11-20 公開日 2022-12-14 最終更新日 2023-02-01 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structures of the entire human opioid receptor family. Cell, 186, 2023
8F7W	Gi bound kappa-opioid receptor in complex with dynorphin 分子名称: CHOLESTEROL, Dynorphin, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Wang, Y, Zhuang, Y, DiBerto, J.F, Zhou, X.E, Schmitz, G.P, Yuan, Q, Jain, M.K, Liu, W, Melcher, K, Jiang, Y, Roth, B.L, Xu, H.E. 登録日 2022-11-20 公開日 2022-12-14 最終更新日 2023-02-01 実験手法 ELECTRON MICROSCOPY (3.19 Å) 主引用文献 Structures of the entire human opioid receptor family. Cell, 186, 2023
8F7R	Gi bound mu-opioid receptor in complex with endomorphin 分子名称: CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... 著者 Wang, Y, Zhuang, Y, DiBerto, J.F, Zhou, X.E, Schmitz, G.P, Yuan, Q, Jain, M.K, Liu, W, Melcher, K, Jiang, Y, Roth, B.L, Xu, H.E. 登録日 2022-11-20 公開日 2022-12-14 最終更新日 2023-02-01 実験手法 ELECTRON MICROSCOPY (3.28 Å) 主引用文献 Structures of the entire human opioid receptor family. Cell, 186, 2023
8F7Q	Gi bound mu-opioid receptor in complex with beta-endorphin 分子名称: Beta-endorphin, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Wang, Y, Zhuang, Y, DiBerto, J.F, Zhou, X.E, Schmitz, G.P, Yuan, Q, Jain, M.K, Liu, W, Melcher, K, Jiang, Y, Roth, B.L, Xu, H.E. 登録日 2022-11-20 公開日 2022-12-14 最終更新日 2023-02-01 実験手法 ELECTRON MICROSCOPY (3.22 Å) 主引用文献 Structures of the entire human opioid receptor family. Cell, 186, 2023
8F7X	Gi bound nociceptin receptor in complex with nociceptin peptide 分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... 著者 Wang, Y, Zhuang, Y, DiBerto, J.F, Zhou, X.E, Schmitz, G.P, Yuan, Q, Jain, M.K, Liu, W, Melcher, K, Jiang, Y, Roth, B.L, Xu, H.E. 登録日 2022-11-20 公開日 2022-12-14 最終更新日 2023-02-01 実験手法 ELECTRON MICROSCOPY (3.28 Å) 主引用文献 Structures of the entire human opioid receptor family. Cell, 186, 2023
8HJ1	GPR21(wt) and Gs complex 分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... 著者 Chen, B, Lin, X, Xu, F. 登録日 2022-11-22 公開日 2023-12-27 実験手法 ELECTRON MICROSCOPY (3.27 Å) 主引用文献 Cryo-EM structures of orphan GPR21 signaling complexes. Nat Commun, 14, 2023
8HJ2	GPR21 wt with G15 complex 分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... 著者 Chen, B, Lin, X, Xu, F. 登録日 2022-11-22 公開日 2023-03-15 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Cryo-EM structures of orphan GPR21 signaling complexes. Nat Commun, 14, 2023
8HJ0	GPR21(m5) and G15 complex 分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... 著者 Chen, B, Lin, X. 登録日 2022-11-22 公開日 2023-03-15 実験手法 ELECTRON MICROSCOPY (3.12 Å) 主引用文献 Cryo-EM structures of orphan GPR21 signaling complexes. Nat Commun, 14, 2023
8HIX	Cryo-EM structure of GPR21_m5_Gs 分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... 著者 Chen, B, Lin, X, Xu, F. 登録日 2022-11-22 公開日 2023-03-15 最終更新日 2023-03-22 実験手法 ELECTRON MICROSCOPY (3.12 Å) 主引用文献 Cryo-EM structures of orphan GPR21 signaling complexes. Nat Commun, 14, 2023
8HJ5	Cryo-EM structure of Gq-coupled MRGPRX1 bound with Compound-16 分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(q) subunit alpha, ... 著者 Gan, B, Yu, L.Y, Ren, R.B. 登録日 2022-11-22 公開日 2023-05-31 最終更新日 2023-12-13 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Mechanism of agonist-induced activation of the human itch receptor MRGPRX1. Plos Biol., 21, 2023
8HK5	C5aR1-Gi-C5a protein complex 分子名称: C5a anaphylatoxin chemotactic receptor 1, Complement C5, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... 著者 Wang, Y, Liu, W, Xu, Y, Zhuang, Y, Xu, H.E. 登録日 2022-11-24 公開日 2023-05-10 最終更新日 2023-11-08 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Revealing the signaling of complement receptors C3aR and C5aR1 by anaphylatoxins. Nat.Chem.Biol., 19, 2023
8HK3	C3aR-Gi-apo protein complex 分子名称: C3a anaphylatoxin chemotactic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... 著者 Wang, Y, Liu, W, Xu, Y, Zhuang, Y, Xu, H.E. 登録日 2022-11-24 公開日 2023-05-10 最終更新日 2023-11-08 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Revealing the signaling of complement receptors C3aR and C5aR1 by anaphylatoxins. Nat.Chem.Biol., 19, 2023
8HK2	C3aR-Gi-C3a protein complex 分子名称: C3a anaphylatoxin, C3a anaphylatoxin chemotactic receptor, CHOLESTEROL, ... 著者 Wang, Y, Liu, W, Xu, Y, Zhuang, Y, Xu, H.E. 登録日 2022-11-24 公開日 2023-05-10 最終更新日 2023-11-08 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Revealing the signaling of complement receptors C3aR and C5aR1 by anaphylatoxins. Nat.Chem.Biol., 19, 2023
8HMP	GPR52 with Gs and c17 分子名称: G-protein coupled receptor 52, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... 著者 Chen, B, Xu, F. 登録日 2022-12-05 公開日 2023-06-21 実験手法 ELECTRON MICROSCOPY (2.77 Å) 主引用文献 Allosteric coupling between G-protein binding and extracellular ligand binding sites in GPR52 revealed by 19 F-NMR and cryo-electron microscopy. MedComm (2020), 4, 2023
8HMV	Structure of GPR21-Gs complex 分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... 著者 Wong, T.S, Gao, W. 登録日 2022-12-05 公開日 2023-03-01 実験手法 ELECTRON MICROSCOPY (2.91 Å) 主引用文献 Cryo-EM structure of orphan G protein-coupled receptor GPR21. MedComm (2020), 4, 2023
8FEG	CryoEM structure of Kappa Opioid Receptor bound to a semi-peptide and Gi1 分子名称: ACE-TYR-ALA-DTY-THR-THR-CYS-THR-DPN-XT9, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... 著者 Fay, J.F, Che, T. 登録日 2022-12-06 公開日 2023-12-06 最終更新日 2024-01-17 実験手法 ELECTRON MICROSCOPY (2.54 Å) 主引用文献 Design and structural validation of peptide-drug conjugate ligands of the kappa-opioid receptor. Nat Commun, 14, 2023
8HN8	Cryo-EM structure of ligand histamine-bound Histamine H4 receptor Gi complex 分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... 著者 Tang, W.Q, Sun, X.Y, Li, F.H, Wang, J.Y. 登録日 2022-12-07 公開日 2023-12-20 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structure insights into Histamine H4 receptor activation by an endogenous ligand histamine and agonist imetit To Be Published
8HNM	CXCR3-DNGi complex activated by VUF11222 分子名称: CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... 著者 Jiao, H.Z, Hu, H.L. 登録日 2022-12-08 公開日 2023-11-29 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (2.94 Å) 主引用文献 Structural insights into the activation and inhibition of CXC chemokine receptor 3. Nat.Struct.Mol.Biol., 31, 2024
8HNK	CXCR3-DNGi complex activated by CXCL11 分子名称: C-X-C motif chemokine 11, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Jiao, H.Z, Hu, H.L. 登録日 2022-12-08 公開日 2023-11-29 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.01 Å) 主引用文献 Structural insights into the activation and inhibition of CXC chemokine receptor 3. Nat.Struct.Mol.Biol., 31, 2024

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