8HMP

GPR52 with Gs and c17

Summary for 8HMP

• Entry DOI: 10.2210/pdb8hmp/pdb
• EMDB information: 34902
• Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Nb35, ... (6 entities in total)
• Functional Keywords: gpcr, structural protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 5
• Total formula weight: 130578.69

Authors

Chen, B.,Xu, F. (deposition date: 2022-12-05, release date: 2023-06-21)

• Primary citation: Fan, Y.,Lin, X.,Pan, B.,Chen, B.,Liu, D.,Wuthrich, K.,Xu, F.; Allosteric coupling between G-protein binding and extracellular ligand binding sites in GPR52 revealed by 19 F-NMR and cryo-electron microscopy.; MedComm (2020), 4:e260-e260, 2023; PubMed: 37051308; DOI: 10.1002/mco2.260

Experimental method

ELECTRON MICROSCOPY (2.77 Å)