8F7W

Gi bound kappa-opioid receptor in complex with dynorphin

Summary for 8F7W

Entry DOI	10.2210/pdb8f7w/pdb
EMDB information	28907 28908 28909 28911 28912
Descriptor	Kappa-type opioid receptor, Dynorphin, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... (8 entities in total)
Functional Keywords	kappa opioid receptor, g protein coupled receptor, dynorphin, signaling protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	6
Total formula weight	158528.68
Authors	Wang, Y.,Zhuang, Y.,DiBerto, J.F.,Zhou, X.E.,Schmitz, G.P.,Yuan, Q.,Jain, M.K.,Liu, W.,Melcher, K.,Jiang, Y.,Roth, B.L.,Xu, H.E. (deposition date: 2022-11-20, release date: 2022-12-14, Last modification date: 2023-02-01)
Primary citation	Wang, Y.,Zhuang, Y.,DiBerto, J.F.,Zhou, X.E.,Schmitz, G.P.,Yuan, Q.,Jain, M.K.,Liu, W.,Melcher, K.,Jiang, Y.,Roth, B.L.,Xu, H.E. Structures of the entire human opioid receptor family. Cell, 186:413-427.e17, 2023 Cited by PubMed: 36638794 DOI: 10.1016/j.cell.2022.12.026 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.19 Å)

Structure validation