8HK2

C3aR-Gi-C3a protein complex

Summary for 8HK2

Entry DOI	10.2210/pdb8hk2/pdb
EMDB information	34842 34843 34846
Descriptor	C3a anaphylatoxin chemotactic receptor, Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... (8 entities in total)
Functional Keywords	gpcr, c3ar, c3a, complement, membrane protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	6
Total formula weight	176747.26
Authors	Wang, Y.,Liu, W.,Xu, Y.,Zhuang, Y.,Xu, H.E. (deposition date: 2022-11-24, release date: 2023-05-10, Last modification date: 2023-11-08)
Primary citation	Wang, Y.,Liu, W.,Xu, Y.,He, X.,Yuan, Q.,Luo, P.,Fan, W.,Zhu, J.,Zhang, X.,Cheng, X.,Jiang, Y.,Xu, H.E.,Zhuang, Y. Revealing the signaling of complement receptors C3aR and C5aR1 by anaphylatoxins. Nat.Chem.Biol., 19:1351-1360, 2023 Cited by PubMed: 37169960 DOI: 10.1038/s41589-023-01339-w PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.9 Å)

Structure validation