3LA3
 
 | | Crystal structure of NtcA in complex with 2,2-difluoropentanedioic acid | | 分子名称: | 2,2-difluoropentanedioic acid, Global nitrogen regulator | | 著者 | Zhao, M.X, Jiang, Y.L, He, Y.X, Chen, Y.F, Teng, Y.B, Chen, Y.X, Zhang, C.C, Zhou, C.Z. | | 登録日 | 2010-01-06 | | 公開日 | 2010-07-14 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural basis for the allosteric control of the global transcription factor NtcA by the nitrogen starvation signal 2-oxoglutarate.
Proc.Natl.Acad.Sci.USA, 107, 2010
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4GFA
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1MNE
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8HW4
 | | Cryo-EM structure of dehydroepiandrosterone sulfate-bound human ABC transporter ABCC3 in nanodiscs | | 分子名称: | 17-oxoandrost-5-en-3beta-yl hydrogen sulfate, ATP-binding cassette sub-family C member 3 | | 著者 | Wang, J, Wang, F.F, Chen, Y.X, Zhou, C.Z. | | 登録日 | 2022-12-28 | | 公開日 | 2023-06-07 | | 最終更新日 | 2023-10-11 | | 実験手法 | ELECTRON MICROSCOPY (3.52 Å) | | 主引用文献 | Placing steroid hormones within the human ABCC3 transporter reveals a compatible amphiphilic substrate-binding pocket.
Embo J., 42, 2023
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6DL2
 | | BRD4 bromodomain 1 in complex with HYB157 | | 分子名称: | 1,2-ETHANEDIOL, 3-benzyl-2,9-dimethyl-4H,6H-thieno[2,3-e][1,2,4]triazolo[3,4-c][1,4]oxazepine, Bromodomain-containing protein 4 | | 著者 | Meagher, J.L, Stuckey, J.A. | | 登録日 | 2018-05-31 | | 公開日 | 2019-04-17 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | | 主引用文献 | Discovery of QCA570 as an Exceptionally Potent and Efficacious Proteolysis Targeting Chimera (PROTAC) Degrader of the Bromodomain and Extra-Terminal (BET) Proteins Capable of Inducing Complete and Durable Tumor Regression.
J. Med. Chem., 61, 2018
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8HW2
 | | Cryo-EM structure of beta-estradiol 17-(beta-D-glucuronide)-bound human ABC transporter ABCC3 in nanodiscs | | 分子名称: | ATP-binding cassette sub-family C member 3, Estradiol-17beta-glucuronide | | 著者 | Wang, J, Wang, F.F, Chen, Y.X, Zhou, C.Z. | | 登録日 | 2022-12-28 | | 公開日 | 2023-06-07 | | 最終更新日 | 2023-10-11 | | 実験手法 | ELECTRON MICROSCOPY (3.65 Å) | | 主引用文献 | Placing steroid hormones within the human ABCC3 transporter reveals a compatible amphiphilic substrate-binding pocket.
Embo J., 42, 2023
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4ZWC
 | | Crystal structure of maltose-bound human GLUT3 in the outward-open conformation at 2.6 angstrom | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Solute carrier family 2, facilitated glucose transporter member 3, ... | | 著者 | Deng, D, Sun, P.C, Yan, C.Y, Yan, N. | | 登録日 | 2015-05-19 | | 公開日 | 2015-07-22 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Molecular basis of ligand recognition and transport by glucose transporters
Nature, 526, 2015
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7S7H
 | | Complex structure of Methane monooxygenase hydroxylase and regulatory subunit DBL2 | | 分子名称: | 1,2-ETHANEDIOL, FE (III) ION, Methane monooxygenase beta chain, ... | | 著者 | Johns, J.C, Banerjee, R, Semonis, M.M, Shi, K, Aihara, H, Lipscomb, J.D. | | 登録日 | 2021-09-16 | | 公開日 | 2021-12-29 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | X-ray Crystal Structures of Methane Monooxygenase Hydroxylase Complexes with Variants of Its Regulatory Component: Correlations with Altered Reaction Cycle Dynamics.
Biochemistry, 61, 2022
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4W4Z
 | | Structure of the EphA4 LBD in complex with peptide | | 分子名称: | APY-bAla8.am peptide, Ephrin type-A receptor 4, GLYCEROL, ... | | 著者 | Lechtenberg, B.C, Mace, P.D, Riedl, S.J. | | 登録日 | 2014-08-15 | | 公開日 | 2014-10-08 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | | 主引用文献 | Development and Structural Analysis of a Nanomolar Cyclic Peptide Antagonist for the EphA4 Receptor.
Acs Chem.Biol., 9, 2014
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8IF5
 | | AFB1-AF26 APTAMER COMPLEX | | 分子名称: | AFB1 DNA aptamer (26-MER), AFLATOXIN B1 | | 著者 | Xu, G.H, Wang, C, Li, C.G. | | 登録日 | 2023-02-17 | | 公開日 | 2023-07-19 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural basis for high-affinity recognition of aflatoxin B1 by a DNA aptamer.
Nucleic Acids Res., 51, 2023
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3LYU
 | | Crystal Structure of the C-terminal domain (residues 83-215) of PF1911 hydrogenase from Pyrococcus furiosus, Northeast Structural Genomics Consortium Target PfR246A | | 分子名称: | Putative hydrogenase | | 著者 | Forouhar, F, Abashidze, M, Seetharaman, J, Sahdev, S, Xiao, R, Foote, E.L, Ciccosanti, C, Belote, R.L, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2010-02-28 | | 公開日 | 2010-03-23 | | 最終更新日 | 2019-07-17 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Northeast Structural Genomics Consortium Target PfR246A
To be Published
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3VCB
 | | C425S mutant of the C-terminal cytoplasmic domain of non-structural protein 4 from mouse hepatitis virus A59 | | 分子名称: | RNA-directed RNA polymerase | | 著者 | Xu, X, Lou, Z, Ma, Y, Chen, X, Yang, Z, Tong, X, Zhao, Q, Xu, Y, Deng, H, Bartlam, M, Rao, Z. | | 登録日 | 2012-01-03 | | 公開日 | 2012-01-11 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal structure of the C-terminal cytoplasmic domain of non-structural protein 4 from mouse hepatitis virus A59.
Plos One, 4, 2009
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2R7X
 | | Crystal Structure of Rotavirus SA11 VP1/RNA (UGUGACC)/GTP complex | | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, RNA (5'-R(*UP*GP*UP*GP*AP*CP*C)-3'), RNA-dependent RNA polymerase | | 著者 | Lu, X, Harrison, S.C, Tao, Y.J, Patton, J.T, Nibert, M.L. | | 登録日 | 2007-09-10 | | 公開日 | 2008-07-29 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Mechanism for coordinated RNA packaging and genome replication by rotavirus polymerase VP1.
Structure, 16, 2008
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8C44
 | | HB3VAR03 apo headstructure (PfEMP1 A) complexed with EPCR | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Endothelial protein C receptor, PHOSPHATIDYLETHANOLAMINE, ... | | 著者 | Raghavan, S.S.R, Lavstsen, T, Wang, K.T. | | 登録日 | 2022-12-31 | | 公開日 | 2023-08-16 | | 最終更新日 | 2023-12-27 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Endothelial protein C receptor binding induces conformational changes to severe malaria-associated group A PfEMP1.
Structure, 31, 2023
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1MZF
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5AG8
 | | CRYSTAL STRUCTURE OF A MUTANT (665I6H) OF THE C-TERMINAL DOMAIN OF RGPB | | 分子名称: | GINGIPAIN R2, GLYCEROL, SULFATE ION | | 著者 | de Diego, I, Ksiazek, M, Mizgalska, D, Golik, P, Szmigielski, B, Nowak, M, Nowakowska, Z, Potempa, B, Koneru, L, Nguyen, K.A, Enghild, J, Thogersen, I.B, Dubin, G, Gomis-Ruth, F.X, Potempa, J. | | 登録日 | 2015-01-29 | | 公開日 | 2016-04-06 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The Outer-Membrane Export Signal of Porphyromonas Gingivalis Type Ix Secretion System (T9Ss) is a Conserved C-Terminal Beta-Sandwich Domain.
Sci.Rep., 6, 2016
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3MEV
 | | Crystal structure of SGF29 in complex with R2AK4me3 | | 分子名称: | GLYCEROL, Histone H3, SAGA-associated factor 29 homolog, ... | | 著者 | Bian, C.B, Xu, C, Lam, R, Bountra, C, Arrowsmith, C.H, Weigelt, J, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC) | | 登録日 | 2010-03-31 | | 公開日 | 2010-04-28 | | 最終更新日 | 2021-10-06 | | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | | 主引用文献 | Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation.
Embo J., 30, 2011
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4GGA
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3VDK
 | | Crystal structure of circumsporozoite protein aTSR domain, R32 platinum-bound form | | 分子名称: | Circumsporozoite (CS) protein, PLATINUM (II) ION | | 著者 | Doud, M.B, Koksal, A.C, Mi, L.Z, Song, G, Lu, C, Springer, T.A. | | 登録日 | 2012-01-05 | | 公開日 | 2012-05-09 | | 最終更新日 | 2012-05-30 | | 実験手法 | X-RAY DIFFRACTION (1.847 Å) | | 主引用文献 | Unexpected fold in the circumsporozoite protein target of malaria vaccines.
Proc.Natl.Acad.Sci.USA, 109, 2012
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5A2T
 | | The Molecular Basis for Flexibility in the Flexible Filamentous Plant Viruses | | 分子名称: | BAMBOO MOSAIC VIRUS, COAT PROTEIN | | 著者 | DiMaio, F, Chen, C.C, Yu, X, Frenz, B, Hsu, Y.H, Lin, N.S, Egelman, E.H. | | 登録日 | 2015-05-23 | | 公開日 | 2015-07-22 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (5.6 Å) | | 主引用文献 | The Molecular Basis for Flexibility in the Flexible Filamentous Plant Viruses.
Nat.Struct.Mol.Biol., 22, 2015
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8C4D
 | | N-acetylmuramoyl-L-alanine amidase from Enterococcus faecium prophage genome | | 分子名称: | CHLORIDE ION, CITRATE ANION, N-acetylmuramoyl-L-alanine amidase, ... | | 著者 | Papageorgiou, A.C, Premetis, G.E, Labrou, N.E. | | 登録日 | 2023-01-03 | | 公開日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | Structural and functional features of a broad-spectrum prophage-encoded enzybiotic from Enterococcus faecium.
Sci Rep, 13, 2023
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1MZE
 | | Human Factor Inhibiting HIF (FIH1) | | 分子名称: | D(-)-TARTARIC ACID, FE (II) ION, factor inhibiting HIF1 | | 著者 | Dann III, C.E, Bruick, R.K, Deisenhofer, J. | | 登録日 | 2002-10-07 | | 公開日 | 2002-11-20 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure of Factor-Inhibiting Hypoxia-Inducible Factor 1: An Asparaginyl Hydroxylase Involved in the Hypoxic Response Pathway
Proc.Natl.Acad.Sci.USA, 99, 2002
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3VJC
 | | Crystal structure of the human squalene synthase in complex with zaragozic acid A | | 分子名称: | MAGNESIUM ION, PHOSPHATE ION, Squalene synthase, ... | | 著者 | Liu, C.I, Jeng, W.Y, Chang, W.J, Ko, T.P, Wang, A.H.J. | | 登録日 | 2011-10-14 | | 公開日 | 2012-04-11 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | | 主引用文献 | Binding modes of zaragozic acid A to human squalene synthase and staphylococcal dehydrosqualene synthase
J.Biol.Chem., 287, 2012
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1N3S
 | | Biosynthesis of pteridins. Reaction mechanism of GTP cyclohydrolase I | | 分子名称: | GTP cyclohydrolase I, GUANOSINE-5'-TRIPHOSPHATE | | 著者 | Rebelo, J, Auerbach, G, Bader, G, Bracher, A, Nar, H, Hoesl, C, Schramek, N, Kaiser, J, Bacher, A, Huber, R, Fischer, M. | | 登録日 | 2002-10-29 | | 公開日 | 2004-03-02 | | 最終更新日 | 2021-11-10 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Biosynthesis of Pteridines. Reaction Mechanism of GTP Cyclohydrolase I
J.MOL.BIOL., 326, 2003
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5AG9
 | | CRYSTAL STRUCTURE OF A MUTANT (665sXa) C-TERMINAL DOMAIN OF RGPB | | 分子名称: | Gingipain R2, SULFATE ION | | 著者 | de Diego, I, Ksiazek, M, Mizgalska, D, Golik, P, Szmigielski, B, Nowak, M, Nowakowska, Z, Potempa, B, Koneru, L, Nguyen, K.A, Enghild, J, Thogersen, I.B, Dubin, G, Gomis-Ruth, F.X, Potempa, J. | | 登録日 | 2015-01-29 | | 公開日 | 2016-04-06 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | | 主引用文献 | The outer-membrane export signal of Porphyromonas gingivalis type IX secretion system (T9SS) is a conserved C-terminal beta-sandwich domain.
Sci Rep, 6, 2016
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