3MEV

Crystal structure of SGF29 in complex with R2AK4me3

Summary for 3MEV

Related3ME9 3MEA 3MET 3MEU 3MEW
DescriptorSAGA-associated factor 29 homolog, Histone H3, SULFATE ION, ... (5 entities in total)
Functional Keywordsstructural genomics consortium, sgc, nucleus, transcription, transcription regulation, chromosomal protein, dna-binding, nucleosome core
Biological sourceHomo sapiens (human)
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Cellular locationNucleus (By similarity) Q96ES7
Total number of polymer chains4
Total molecular weight42655.78
Authors
Bian, C.B.,Xu, C.,Lam, R.,Bountra, C.,Arrowsmith, C.H.,Weigelt, J.,Edwards, A.M.,Bochkarev, A.,Min, J.,Structural Genomics Consortium (SGC) (deposition date: 2010-03-31, release date: 2010-04-28, Last modification date: 2012-05-09)
Primary citation
Bian, C.,Xu, C.,Ruan, J.,Lee, K.K.,Burke, T.L.,Tempel, W.,Barsyte, D.,Li, J.,Wu, M.,Zhou, B.O.,Fleharty, B.E.,Paulson, A.,Allali-Hassani, A.,Zhou, J.Q.,Mer, G.,Grant, P.A.,Workman, J.L.,Zang, J.,Min, J.
Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation.
Embo J., 30:2829-2842, 2011
PubMed: 21685874 (PDB entries with the same primary citation)
DOI: 10.1038/emboj.2011.193
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.83 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.274400.7%2.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution