Crystal structure of SGF29 in complex with R2AK4me3

Summary for 3MEV

Related3ME9 3MEA 3MET 3MEU 3MEW
DescriptorSAGA-associated factor 29 homolog, Histone H3, SULFATE ION, ... (5 entities in total)
Functional Keywordsstructural genomics consortium, sgc, nucleus, transcription, transcription regulation, chromosomal protein, dna-binding, nucleosome core
Biological sourceHomo sapiens (human)
Cellular locationNucleus (By similarity) Q96ES7
Total number of polymer chains4
Total molecular weight42655.78
Bian, C.B.,Xu, C.,Lam, R.,Bountra, C.,Arrowsmith, C.H.,Weigelt, J.,Edwards, A.M.,Bochkarev, A.,Min, J.,Structural Genomics Consortium (SGC) (deposition date: 2010-03-31, release date: 2010-04-28, Last modification date: 2012-05-09)
Primary citation
Bian, C.,Xu, C.,Ruan, J.,Lee, K.K.,Burke, T.L.,Tempel, W.,Barsyte, D.,Li, J.,Wu, M.,Zhou, B.O.,Fleharty, B.E.,Paulson, A.,Allali-Hassani, A.,Zhou, J.Q.,Mer, G.,Grant, P.A.,Workman, J.L.,Zang, J.,Min, J.
Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation.
Embo J., 30:2829-2842, 2011
PubMed: 21685874 (PDB entries with the same primary citation)
DOI: 10.1038/emboj.2011.193
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.274400.7%2.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-09-16