1MZF
Human Factor inhibiting HIF (FIH1) in Complex with 2-oxoglutarate
Summary for 1MZF
Entry DOI | 10.2210/pdb1mzf/pdb |
Related | 1mze |
Descriptor | factor inhibiting HIF1, FE (II) ION, 2-OXOGLUTARIC ACID, ... (4 entities in total) |
Functional Keywords | beta-jellyroll, oxidoreductase |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus (Potential): Q9NWT6 |
Total number of polymer chains | 1 |
Total formula weight | 40658.35 |
Authors | Dann III, C.E.,Bruick, R.K.,Deisenhofer, J. (deposition date: 2002-10-07, release date: 2002-11-20, Last modification date: 2024-04-03) |
Primary citation | Dann III, C.E.,Bruick, R.K.,Deisenhofer, J. Structure of Factor-Inhibiting Hypoxia-Inducible Factor 1: An Asparaginyl Hydroxylase Involved in the Hypoxic Response Pathway. Proc.Natl.Acad.Sci.USA, 99:15351-15356, 2002 Cited by PubMed: 12432100DOI: 10.1073/pnas.202614999 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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