4W4Z
Structure of the EphA4 LBD in complex with peptide
Summary for 4W4Z
Entry DOI | 10.2210/pdb4w4z/pdb |
Related | 4W50 |
Descriptor | Ephrin type-A receptor 4, APY-bAla8.am peptide, HEXANE-1,6-DIOL, ... (5 entities in total) |
Functional Keywords | protein-inhibitor complex, ligand binding domain, signal transduction, receptor-tyrosine kinase, cyclic peptide, epha4, phage display, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 8 |
Total formula weight | 89691.57 |
Authors | Lechtenberg, B.C.,Mace, P.D.,Riedl, S.J. (deposition date: 2014-08-15, release date: 2014-10-08, Last modification date: 2023-12-27) |
Primary citation | Lamberto, I.,Lechtenberg, B.C.,Olson, E.J.,Mace, P.D.,Dawson, P.E.,Riedl, S.J.,Pasquale, E.B. Development and Structural Analysis of a Nanomolar Cyclic Peptide Antagonist for the EphA4 Receptor. Acs Chem.Biol., 9:2787-2795, 2014 Cited by PubMed: 25268696DOI: 10.1021/cb500677x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.41 Å) |
Structure validation
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