4W4Z

Structure of the EphA4 LBD in complex with peptide

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue HEZ A 301

Chain	Residue
A	SER48
A	ASN81
A	TRP83
A	ILE137
A	GLU139

---

site_id	AC2
Number of Residues	7
Details	binding site for residue HEZ A 302

Chain	Residue
D	SER153
D	THR168
D	HOH434
A	SER153
A	THR168
A	GLU169
A	ILE170

---

site_id	AC3
Number of Residues	4
Details	binding site for residue GOL A 303

Chain	Residue
A	GLU30
A	GLU100
A	ARG198
D	ASP151

---

site_id	AC4
Number of Residues	6
Details	binding site for residue GOL A 304

Chain	Residue
A	ARG96
A	GLY174
B	ASP161
D	GLN95
D	TYR98
D	HEZ303

---

site_id	AC5
Number of Residues	4
Details	binding site for residue GOL A 305

Chain	Residue
A	LEU34
A	ASP35
A	SER38
D	GLY28

---

site_id	AC6
Number of Residues	8
Details	binding site for residue HEZ B 301

Chain	Residue
B	TYR98
B	ILE170
B	ARG171
B	LYS202
B	HOH422
C	ILE170
C	ASP172
C	LYS202

---

site_id	AC7
Number of Residues	8
Details	binding site for residue HEZ B 302

Chain	Residue
B	SER153
B	THR168
B	GLU169
B	ILE170
C	SER153
C	THR168
C	GLU169
C	ILE170

---

site_id	AC8
Number of Residues	9
Details	binding site for residue GOL B 303

Chain	Residue
B	GLY52
B	GLY53
B	GLU55
B	GLN71
B	VAL72
B	CYS73
B	ASN74
F	PRO2
F	HOH102

---

site_id	AC9
Number of Residues	5
Details	binding site for residue GOL B 304

Chain	Residue
B	TRP83
B	ARG85
B	PHE136
B	ILE137
B	HOH438

---

site_id	AD1
Number of Residues	3
Details	binding site for residue GOL B 305

Chain	Residue
B	ARG96
B	VAL173
B	GLY174

---

site_id	AD2
Number of Residues	3
Details	binding site for residue GOL B 306

Chain	Residue
B	THR32
B	LEU34
B	ASP35

---

site_id	AD3
Number of Residues	9
Details	binding site for residue GOL C 301

Chain	Residue
A	ILE59
A	MET60
A	ILE159
A	ARG162
C	GLN95
C	PRO175
C	LEU176
C	SER177
E	ARG7

---

site_id	AD4
Number of Residues	5
Details	binding site for residue GOL C 302

Chain	Residue
B	TYR98
B	LYS202
C	ARG96
C	ASP172
C	GLY174

---

site_id	AD5
Number of Residues	5
Details	binding site for residue GOL C 303

Chain	Residue
B	GLY28
C	LEU33
C	LEU34
C	ASP35
C	SER38

---

site_id	AD6
Number of Residues	4
Details	binding site for residue GOL C 304

Chain	Residue
C	SER48
C	TRP83
C	ILE137
C	GLU139

---

site_id	AD7
Number of Residues	7
Details	binding site for residue HEZ D 301

Chain	Residue
A	ILE170
A	LYS202
D	ILE170
D	ARG171
D	ASP172
D	LYS202
D	HOH422

---

site_id	AD8
Number of Residues	6
Details	binding site for residue HEZ D 302

Chain	Residue
D	SER48
D	ASN81
D	PHE136
D	ILE137
D	GLU139
D	PHE142

---

site_id	AD9
Number of Residues	8
Details	binding site for residue HEZ D 303

Chain	Residue
D	GLY93
D	ALA94
D	GLN95
D	ARG96
D	TYR98
D	TYR201
D	LYS202
A	GOL304

---

site_id	AE1
Number of Residues	4
Details	binding site for residue GOL D 304

Chain	Residue
D	ARG96
D	ASP172
D	VAL173
D	GLY174

---

site_id	AE2
Number of Residues	7
Details	binding site for residue GOL D 305

Chain	Residue
A	GLY28
A	LYS203
D	THR32
D	LEU33
D	ASP35
D	SER38
D	VAL39

---

site_id	AE3
Number of Residues	5
Details	binding site for residue GOL H 101

Chain	Residue
H	PRO2
H	TYR3
H	SER11
H	CYS12
H	NH213

---

site_id	AE4
Number of Residues	9
Details	binding site for Di-peptide ARG E 7 and BAL E 8

Chain	Residue
A	ILE59
C	GLU128
C	PRO175
C	SER177
C	GOL301
E	VAL5
E	TYR6
E	SER9
E	HOH102

---

site_id	AE5
Number of Residues	7
Details	binding site for Di-peptide BAL E 8 and SER E 9

Chain	Residue
A	ARG162
E	TYR6
E	ARG7
E	TRP10
E	SER11
E	HOH102
E	HOH103

---

site_id	AE6
Number of Residues	3
Details	binding site for Di-peptide CYS E 12 and NH2 E 13

Chain	Residue
E	TYR3
E	CYS4
E	SER11

---

site_id	AE7
Number of Residues	4
Details	binding site for Di-peptide ARG F 7 and BAL F 8

Chain	Residue
B	ARG162
D	PRO175
F	TYR6
F	SER9

---

site_id	AE8
Number of Residues	5
Details	binding site for Di-peptide BAL F 8 and SER F 9

Chain	Residue
B	ARG162
F	TYR6
F	ARG7
F	TRP10
F	SER11

---

site_id	AE9
Number of Residues	3
Details	binding site for Di-peptide CYS F 12 and NH2 F 13

Chain	Residue
F	TYR3
F	CYS4
F	SER11

---

site_id	AF1
Number of Residues	5
Details	binding site for Di-peptide ARG G 7 and BAL G 8

Chain	Residue
C	ILE59
G	VAL5
G	TYR6
G	SER9
G	HOH101

---

site_id	AF2
Number of Residues	5
Details	binding site for Di-peptide BAL G 8 and SER G 9

Chain	Residue
C	ARG162
G	TYR6
G	ARG7
G	TRP10
G	SER11

---

site_id	AF3
Number of Residues	3
Details	binding site for Di-peptide CYS G 12 and NH2 G 13

Chain	Residue
G	TYR3
G	CYS4
G	SER11

---

site_id	AF4
Number of Residues	4
Details	binding site for Di-peptide ARG H 7 and BAL H 8

Chain	Residue
D	ILE59
H	VAL5
H	TYR6
H	SER9

---

site_id	AF5
Number of Residues	5
Details	binding site for Di-peptide BAL H 8 and SER H 9

Chain	Residue
D	ARG162
H	VAL5
H	TYR6
H	ARG7
H	TRP10

---

site_id	AF6
Number of Residues	4
Details	binding site for Di-peptide CYS H 12 and NH2 H 13

Chain	Residue
H	TYR3
H	CYS4
H	SER11
H	GOL101

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