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1IFR
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BU of 1ifr by Molmil
Structure of Lamin A/C Globular Domain
分子名称: GLYCEROL, Lamin A/C
著者Dhe-Paganon, S, Werner, E.D, Shoelson, S.E.
登録日2001-04-13
公開日2002-07-17
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structure of the globular tail of nuclear lamin.
J.Biol.Chem., 277, 2002
1IVT
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BU of 1ivt by Molmil
NMR structures of the C-terminal globular domain of human lamin A/C
分子名称: Lamin A/C
著者Krimm, I, Ostlund, C, Gilquin, B, Couprie, J, Hossenlopp, P, Mornon, J.P, Bonn, G, Courvalin, J.C, Worman, H.J, Zinn-Justin, S.
登録日2002-03-29
公開日2002-08-21
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献The Ig-like structure of the C-terminal domain of lamin A/C, mutated in muscular dystrophies, cardiomyopathy, and partial lipodystrophy.
Structure, 10, 2002
6NUB
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BU of 6nub by Molmil
Pyruvate Kinase M2 Mutant - S437Y in Complex with L-serine
分子名称: 1,2-ETHANEDIOL, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, ...
著者Srivastava, D, Nandi, S, Dey, M.
登録日2019-01-31
公開日2019-08-21
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Mechanistic and Structural Insights into Cysteine-Mediated Inhibition of Pyruvate Kinase Muscle Isoform 2.
Biochemistry, 58, 2019
1JEY
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BU of 1jey by Molmil
Crystal Structure of the Ku heterodimer bound to DNA
分子名称: DNA (34-MER), DNA (5'-D(*GP*TP*TP*TP*TP*TP*AP*GP*TP*TP*TP*AP*TP*TP*GP*GP*GP*CP*GP*CP*G)-3'), Ku70, ...
著者Walker, J.R, Corpina, R.A, Goldberg, J.
登録日2001-06-19
公開日2001-08-10
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of the Ku heterodimer bound to DNA and its implications for double-strand break repair.
Nature, 412, 2001
6NRA
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hTRiC-hPFD Class1 (No PFD)
分子名称: T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, T-complex protein 1 subunit delta, ...
著者Gestaut, D.R, Roh, S.H, Ma, B, Pintilie, G, Joachimiak, L.A, Leitner, A, Walzthoeni, T, Aebersold, R, Chiu, W, Frydman, J.
登録日2019-01-23
公開日2019-06-19
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (7.7 Å)
主引用文献The Chaperonin TRiC/CCT Associates with Prefoldin through a Conserved Electrostatic Interface Essential for Cellular Proteostasis.
Cell, 177, 2019
6NU1
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BU of 6nu1 by Molmil
Crystal Structure of Human PKM2 in Complex with L-cysteine
分子名称: 1,6-di-O-phosphono-beta-D-fructofuranose, CYSTEINE, MAGNESIUM ION, ...
著者Srivastava, D, Nandi, S, Dey, M.
登録日2019-01-30
公開日2019-08-21
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Mechanistic and Structural Insights into Cysteine-Mediated Inhibition of Pyruvate Kinase Muscle Isoform 2.
Biochemistry, 58, 2019
6NQ3
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Crystal Structure of a SUZ12-RBBP4-PHF19-JARID2 Heterotetrameric Complex
分子名称: Histone-binding protein RBBP4, PHD finger protein 19, Polycomb protein SUZ12, ...
著者Chen, S, Jiao, L, Liu, X.
登録日2019-01-19
公開日2020-01-29
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.89 Å)
主引用文献A Dimeric Structural Scaffold for PRC2-PCL Targeting to CpG Island Chromatin.
Mol.Cell, 77, 2020
6NRC
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BU of 6nrc by Molmil
hTRiC-hPFD Class3
分子名称: Prefoldin subunit 1, Prefoldin subunit 2, Prefoldin subunit 3, ...
著者Gestaut, D, Roh, S.H, Ma, B, Pintilie, G, Joachimiak, L.A, Leitner, A, Walzthoeni, T, Aebersold, R, Chiu, W, Frydman, J.
登録日2019-01-23
公開日2019-06-19
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (8.3 Å)
主引用文献The Chaperonin TRiC/CCT Associates with Prefoldin through a Conserved Electrostatic Interface Essential for Cellular Proteostasis.
Cell, 177, 2019
1H88
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CRYSTAL STRUCTURE OF TERNARY PROTEIN-DNA COMPLEX1
分子名称: AMMONIUM ION, CCAAT/ENHANCER BINDING PROTEIN BETA, DNA(5'-(*CP*CP*AP*GP*TP*CP*CP*GP*TP*TP*AP* AP*GP*GP*AP*TP*TP*GP*CP*GP*CP*CP*AP*CP*AP*T)-3'), ...
著者Tahirov, T.H, Ogata, K.
登録日2001-01-29
公開日2002-01-28
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Mechanism of C-Myb-C/Ebpbeta Cooperation from Separated Sites on a Promoter
Cell(Cambridge,Mass.), 108, 2002
6NU5
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Pyruvate Kinase M2 Mutant - S437Y in Complex with L-cysteine
分子名称: 1,2-ETHANEDIOL, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CYSTEINE, ...
著者Srivastava, D, Nandi, S, Dey, M.
登録日2019-01-30
公開日2019-08-21
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Mechanistic and Structural Insights into Cysteine-Mediated Inhibition of Pyruvate Kinase Muscle Isoform 2.
Biochemistry, 58, 2019
6O1D
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BU of 6o1d by Molmil
Cryo-EM structure of the centromeric nucleosome with native alpha satellite DNA
分子名称: DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
著者Zhou, B.-R.
登録日2019-02-19
公開日2019-05-22
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.395 Å)
主引用文献Atomic resolution cryo-EM structure of a native-like CENP-A nucleosome aided by an antibody fragment.
Nat Commun, 10, 2019
6NR8
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BU of 6nr8 by Molmil
hTRiC-hPFD Class6
分子名称: Prefoldin subunit 1, Prefoldin subunit 2, Prefoldin subunit 3, ...
著者Gestaut, D.R, Roh, S.H, Ma, B, Pintilie, G, Joachimiak, L.A, Leitner, A, Walzthoeni, T, Aebersold, R, Chiu, W, Frydman, J.
登録日2019-01-23
公開日2019-06-19
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (7.8 Å)
主引用文献The Chaperonin TRiC/CCT Associates with Prefoldin through a Conserved Electrostatic Interface Essential for Cellular Proteostasis.
Cell, 177, 2019
1GU4
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BU of 1gu4 by Molmil
Crystal structure of C/EBPBETA BZIP homodimer bound to a high affinity DNA fragment
分子名称: 5'-D(*AP*AP*TP*AP*TP*TP*GP*CP*GP*CP* AP*AP*TP*CP*CP*T)-3', 5'-D(*TP*AP*GP*GP*AP*TP*TP*GP*CP*GP* CP*AP*AP*TP*AP*T)-3', CAAT/ENHANCER BINDING PROTEIN BETA
著者Tahirov, T.H, Ogata, K.
登録日2002-01-23
公開日2003-06-26
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural Basis for Flexible Base Recognition by C/Ebpbeta
To be Published
1GU5
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Crystal structure of C/EBPBETA BZIP homodimer bound to a DNA fragment from the MIM-1 promoter
分子名称: 5'-D(*AP*TP*GP*AP*TP*TP*GP*GP*CP*CP* AP*AP*CP*AP*CP*A)-3', 5'-D(*TP*TP*GP*TP*GP*TP*TP*GP*GP*CP* CP*AP*AP*TP*CP*A)-3', CAAT/ENHANCER BINDING PROTEIN BETA
著者Tahirov, T.H, Ogata, K.
登録日2002-01-24
公開日2003-06-26
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Basis for Flexible Base Recognition by C/Ebpbeta
To be Published
1GTW
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BU of 1gtw by Molmil
crystal structure of C/EBPbeta bZip homodimer bound to a DNA fragment from the tom-1A promoter
分子名称: 5'-D(*AP*AP*TP*GP*TP*GP*GP*CP*GP*CP* AP*AP*TP*CP*CP*T)-3', 5'-D(*TP*AP*GP*GP*AP*TP*TP*GP*CP*GP* CP*CP*AP*CP*AP*T)-3', CAAT/ENHANCER BINDING PROTEIN BETA
著者Tahirov, T.H, Ogata, K.
登録日2002-01-22
公開日2004-02-06
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural Basis for Flexible Base Recognition by C/Ebpbeta
To be Published
6OLF
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BU of 6olf by Molmil
Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AA and PE tRNAs
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
著者Li, W, Cate, J.H.D.
登録日2019-04-16
公開日2019-06-19
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Nat.Struct.Mol.Biol., 26, 2019
6OM7
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BU of 6om7 by Molmil
Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like small molecule with AA and PE tRNAs
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
著者Li, W, Cate, J.H.D.
登録日2019-04-18
公開日2019-06-19
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Nat.Struct.Mol.Biol., 26, 2019
1K5D
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BU of 1k5d by Molmil
Crystal structure of Ran-GPPNHP-RanBP1-RanGAP complex
分子名称: GTP-binding nuclear protein RAN, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
著者Seewald, M.J, Koerner, C, Wittinghofer, A, Vetter, I.R.
登録日2001-10-10
公開日2002-02-13
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献RanGAP mediates GTP hydrolysis without an arginine finger.
Nature, 415, 2002
6OWJ
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BU of 6owj by Molmil
Zn-mediated polymerization of human SFPQ
分子名称: Splicing factor, proline- and glutamine-rich, ZINC ION
著者Lee, M.
登録日2019-05-10
公開日2020-02-05
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Structural basis of the zinc-induced cytoplasmic aggregation of the RNA-binding protein SFPQ.
Nucleic Acids Res., 48, 2020
1K4T
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BU of 1k4t by Molmil
HUMAN DNA TOPOISOMERASE I (70 KDA) IN COMPLEX WITH THE POISON TOPOTECAN AND COVALENT COMPLEX WITH A 22 BASE PAIR DNA DUPLEX
分子名称: (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE, 2-(1-DIMETHYLAMINOMETHYL-2-HYDROXY-8-HYDROXYMETHYL-9-OXO-9,11-DIHYDRO-INDOLIZINO[1,2-B]QUINOLIN-7-YL)-2-HYDROXY-BUTYRIC ACID, 5'-D(*(TGP)P*GP*AP*AP*AP*AP*AP*TP*TP*TP*TP*T)-3', ...
著者Staker, B.L, Hjerrild, K, Feese, M.D, Behnke, C.A, Burgin Jr, A.B, Stewart, L.J.
登録日2001-10-08
公開日2002-12-04
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The mechanism of topoisomerase I poisoning by a camptothecin analog
Proc.Natl.Acad.Sci.USA, 99, 2002
1K4S
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HUMAN DNA TOPOISOMERASE I IN COVALENT COMPLEX WITH A 22 BASE PAIR DNA DUPLEX
分子名称: 5'-D(*(SPT)P*GP*AP*AP*AP*AP*AP*(5IU)P*(5IU)P*(5IU)P*(5IU)P*T)-3', 5'-D(*AP*AP*AP*AP*AP*GP*AP*CP*(5IU)P*(5IU))-3', 5'-D(*AP*AP*AP*AP*AP*TP*(IDO)UP*(IDO)UP*(IDO)UP*(IDO)UP*CP*AP*AP*AP*GP*(IDO)UP*CP*(IDO)UP*(IDO)UP*(IDO)UP*(IDO)UP*T)-3', ...
著者Staker, B.L, Hjerrild, K, Feese, M.D, Behnke, C.A, Burgin Jr, A.B, Stewart, L.J.
登録日2001-10-08
公開日2002-12-04
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献The mechanism of topoisomerase I poisoning by a camptothecin analog
Proc.Natl.Acad.Sci.USA, 99, 2002
1K5G
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BU of 1k5g by Molmil
Crystal structure of Ran-GDP-AlFx-RanBP1-RanGAP complex
分子名称: ALUMINUM FLUORIDE, GTP-binding nuclear protein RAN, GUANOSINE-5'-DIPHOSPHATE, ...
著者Seewald, M.J, Koerner, C, Wittinghofer, A, Vetter, I.R.
登録日2001-10-10
公開日2002-02-13
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献RanGAP mediates GTP hydrolysis without an arginine finger.
Nature, 415, 2002
1JEQ
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Crystal Structure of the Ku Heterodimer
分子名称: KU70, KU80
著者Walker, J.R, Corpina, R.A, Goldberg, J.
登録日2001-06-18
公開日2001-08-15
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure of the Ku heterodimer bound to DNA and its implications for double-strand break repair.
Nature, 412, 2001
1KHM
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C-TERMINAL KH DOMAIN OF HNRNP K (KH3)
分子名称: PROTEIN (HNRNP K)
著者Baber, J, Libutti, D, Levens, D, Tjandra, N.
登録日1999-01-07
公開日2000-01-12
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献High precision solution structure of the C-terminal KH domain of heterogeneous nuclear ribonucleoprotein K, a c-myc transcription factor.
J.Mol.Biol., 289, 1999
1HJB
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CRYSTAL STRUCTURE OF RUNX-1/AML1/CBFALPHA RUNT DOMAIN AND C/EBPBETA BZIP HOMODIMER BOUND TO A DNA FRAGMENT FROM THE CSF-1R PROMOTER
分子名称: CCAAT/ENHANCER BINDING PROTEIN BETA, DNA (5'-(*CP*CP*GP*CP*AP*AP*CP*CP*AP*CP* AP*GP*AP*GP*TP*TP*TP*GP*GP*AP*AP*AP*TP*CP*TP*T)-3'), DNA (5'-(*GP*AP*AP*GP*AP*TP*TP*TP*CP*CP* AP*AP*AP*CP*TP*CP*TP*GP*TP*GP*GP*TP*TP*GP*CP*G)-3'), ...
著者Tahirov, T.H, Ogata, K.
登録日2001-01-11
公開日2001-03-09
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural Analyses of DNA Recognition by the Aml1/Runx-1 Runt Domain and its Allosteric Control by Cbfbeta
Cell(Cambridge,Mass.), 104, 2001

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