1HJB

CRYSTAL STRUCTURE OF RUNX-1/AML1/CBFALPHA RUNT DOMAIN AND C/EBPBETA BZIP HOMODIMER BOUND TO A DNA FRAGMENT FROM THE CSF-1R PROMOTER

Summary for 1HJB

• Entry DOI: 10.2210/pdb1hjb/pdb
• Related: 1CL3 1CMO 1CO1 1E50 1HJC 1IO4 1JHB
• Descriptor: CCAAT/ENHANCER BINDING PROTEIN BETA, RUNT-RELATED TRANSCRIPTION FACTOR 1, DNA (5'-(*GP*AP*AP*GP*AP*TP*TP*TP*CP*CP* AP*AP*AP*CP*TP*CP*TP*GP*TP*GP*GP*TP*TP*GP*CP*G)-3'), ... (4 entities in total)
• Functional Keywords: transcription/dna, protein-dna complex, transcription factor, bzip, runx, runt, c/ebp, cbf, core binding factor, aml1, aml, transcription-dna complex
• Biological source: HOMO SAPIENS (HUMAN); More
• Total number of polymer chains: 10
• Total formula weight: 100375.54

Authors

Tahirov, T.H.,Ogata, K. (deposition date: 2001-01-11, release date: 2001-03-09, Last modification date: 2023-12-13)

• Primary citation: Tahirov, T.H.,Inoue-Bungo, T.,Morii, H.,Fujikawa, A.,Sasaki, M.,Kimura, K.,Shiina, M.,Sato, K.,Kumasaka, T.,Yamamoto, M.,Ishii, S.,Ogata, K.; Structural Analyses of DNA Recognition by the Aml1/Runx-1 Runt Domain and its Allosteric Control by Cbfbeta; Cell(Cambridge,Mass.), 104:755-, 2001; PubMed: 11257229; DOI: 10.1016/S0092-8674(01)00271-9

Experimental method

X-RAY DIFFRACTION (3 Å)