6NUB

Pyruvate Kinase M2 Mutant - S437Y in Complex with L-serine

Summary for 6NUB

Entry DOI	10.2210/pdb6nub/pdb
Descriptor	Pyruvate kinase PKM, 1,2-ETHANEDIOL, SERINE, ... (11 entities in total)
Functional Keywords	glycolysis, gene regulation, phosphotransferase, serine, transferase
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	121982.91
Authors	Srivastava, D.,Nandi, S.,Dey, M. (deposition date: 2019-01-31, release date: 2019-08-21, Last modification date: 2023-10-11)
Primary citation	Srivastava, D.,Nandi, S.,Dey, M. Mechanistic and Structural Insights into Cysteine-Mediated Inhibition of Pyruvate Kinase Muscle Isoform 2. Biochemistry, 58:3669-3682, 2019 Cited by PubMed: 31386812 DOI: 10.1021/acs.biochem.9b00349 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation