Crystal Structure of the Ku heterodimer bound to DNA

Summary for 1JEY

DescriptorDNA (5'-D(*GP*TP*TP*TP*TP*TP*AP*GP*TP*TP*TP*AP*TP*TP*GP*GP*GP*CP*GP*CP*G)-3'), DNA (34-MER), Ku70, ... (5 entities in total)
Functional Keywordsdouble-strand dna break repair, non-homologous end-joining, protein-nucleic acid complex, alpha/beta domain, beta barrel, helical c-terminal arm, sap domain, dna binding protein-dna complex, dna binding protein/dna
Biological sourceHomo sapiens (human)
Cellular locationNucleus  P12956 P13010
Total number of polymer chains4
Total molecular weight150967.46
Walker, J.R.,Corpina, R.A.,Goldberg, J. (deposition date: 2001-06-19, release date: 2001-08-10, Last modification date: 2018-02-14)
Primary citation
Walker, J.R.,Corpina, R.A.,Goldberg, J.
Structure of the Ku heterodimer bound to DNA and its implications for double-strand break repair.
Nature, 412:607-614, 2001
PubMed: 11493912 (PDB entries with the same primary citation)
DOI: 10.1038/35088000
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliers15 0.6% 2.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-12-02