1K5D

Crystal structure of Ran-GPPNHP-RanBP1-RanGAP complex

Summary for 1K5D
Related1K5G
DescriptorGTP-binding nuclear protein RAN, Ran-specific GTPase-activating protein, Ran GTPase activating protein 1, ... (6 entities in total)
Functional Keywordsran, ranbp1, rangap, gap, signal transduction, nuclear transport, gtp hydrolysis, ground state, complex (gtp-binding-gtpase activation), signaling protein-signaling activator complex, signaling protein/signaling activator
Biological sourceHomo sapiens (human)
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Cellular locationNucleus: P62826
Cytoplasm: P41391
Total number of polymer chains12
Total formula weight366509.83
Authors
Seewald, M.J.,Koerner, C.,Wittinghofer, A.,Vetter, I.R. (deposition date: 2001-10-10, release date: 2002-02-13, Last modification date: 2011-07-13)
Primary citationKorner, C.,Seewald, M.J.,Vetter, I.R.,Wittinghofer, A.
RanGAP mediates GTP hydrolysis without an arginine finger.
Nature, 415:662-666, 2002
PubMed: 11832950
DOI: 110.1038/415662a
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.7 Å)
Structure validation
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PDB entries from 2021-06-09