1K5D

Crystal structure of Ran-GPPNHP-RanBP1-RanGAP complex

Summary for 1K5D

• Entry DOI: 10.2210/pdb1k5d/pdb
• Related: 1K5G
• Descriptor: GTP-binding nuclear protein RAN, Ran-specific GTPase-activating protein, Ran GTPase activating protein 1, ... (6 entities in total)
• Functional Keywords: ran, ranbp1, rangap, gap, signal transduction, nuclear transport, gtp hydrolysis, ground state, complex (gtp-binding-gtpase activation), signaling protein-signaling activator complex, signaling protein/signaling activator
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus: P62826; Cytoplasm: P41391
• Total number of polymer chains: 12
• Total formula weight: 366509.83

Authors

Seewald, M.J.,Koerner, C.,Wittinghofer, A.,Vetter, I.R. (deposition date: 2001-10-10, release date: 2002-02-13, Last modification date: 2023-08-16)

• Primary citation: Seewald, M.J.,Korner, C.,Wittinghofer, A.,Vetter, I.R.; RanGAP mediates GTP hydrolysis without an arginine finger.; Nature, 415:662-666, 2002; PubMed: 11832950; DOI: 10.1038/415662a

Experimental method

X-RAY DIFFRACTION (2.7 Å)