1K5D
Crystal structure of Ran-GPPNHP-RanBP1-RanGAP complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D, G, J | GTP-binding nuclear protein RAN | polymer | 216 | 24456.1 | 4 | UniProt (P62826) Pfam (PF00071) In PDB | Homo sapiens (human) | Ran, TC4, Ran GTPase, Androgen receptor-associated protein 24 |
| 2 | B, E, H, K | Ran-specific GTPase-activating protein | polymer | 201 | 23352.2 | 4 | UniProt (P43487) Pfam (PF00638) In PDB | Homo sapiens (human) | RanBP1, Ran binding protein 1 |
| 3 | C, F, I, L | Ran GTPase activating protein 1 | polymer | 386 | 43272.7 | 4 | UniProt (P41391) In PDB | Schizosaccharomyces pombe (fission yeast) | RanGAP, Protein rna1 |
| 4 | A, D, G, J | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 5 | A, D, G, J | PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | non-polymer | 522.2 | 4 | Chemie (GNP) | |||
| 6 | water | water | 18.0 | 342 | Chemie (HOH) |
Sequence modifications
C, F, I, L: 1 - 386 (UniProt: P41391)
| PDB | External Database | Details |
|---|---|---|
| Ala 2 | Ser 2 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 364323.8 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 2186.0 | |
| All* | Total formula weight | 366509.8 |
