7U6K
| Isoreticular, interpenetrating co-crystal of Replication Initiator Protein REPE54 and symmetrical expanded duplex (31mer) containing the cognate REPE54 sequence and an additional G-C rich sequence. | 分子名称: | DNA (5'-D(A*CP*CP*CP*GP*GP*AP*CP*CP*TP*GP*TP*GP*AP*CP*AP*AP*AP*TP*TP*GP*CP*CP*CP*TP*CP*AP*GP*AP*CP*GP*G)-3'), DNA (5'-D(A*GP*GP*CP*CP*GP*TP*CP*TP*GP*AP*GP*GP*GP*CP*AP*AP*TP*TP*TP*GP*TP*CP*AP*CP*AP*GP*GP*TP*CP*CP*G)-3'), MAGNESIUM ION, ... | 著者 | Ward, A.R, Snow, C.D. | 登録日 | 2022-03-04 | 公開日 | 2023-03-29 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | 主引用文献 | Modular Protein-DNA Cocrystals as Precise, Programmable Assembly Scaffolds. Acs Nano, 17, 2023
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5VVR
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4RKH
| Structure of the MSL2 CXC domain bound with a specific MRE sequence | 分子名称: | DNA (5'-D(*AP*TP*CP*CP*AP*TP*CP*TP*CP*GP*CP*TP*CP*AP*T)-3'), DNA (5'-D(*AP*TP*GP*AP*GP*CP*GP*AP*GP*AP*TP*GP*GP*AP*T)-3'), E3 ubiquitin-protein ligase msl-2, ... | 著者 | Zheng, S, Ye, K. | 登録日 | 2014-10-13 | 公開日 | 2015-01-21 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural basis of X chromosome DNA recognition by the MSL2 CXC domain during Drosophila dosage compensation. Genes Dev., 28, 2014
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4U7B
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5VVS
| RNA pol II elongation complex | 分子名称: | DNA (NTS), DNA (TS), DNA-directed RNA polymerase II subunit RPB1, ... | 著者 | Lahiri, I, Leschziner, A.E. | 登録日 | 2017-05-20 | 公開日 | 2017-11-22 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (6.4 Å) | 主引用文献 | Structural basis for the initiation of eukaryotic transcription-coupled DNA repair. Nature, 551, 2017
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8BOT
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1SFO
| RNA POLYMERASE II STRAND SEPARATED ELONGATION COMPLEX | 分子名称: | DNA STRAND, DNA-directed RNA polymerase II 13.6 kDa polypeptide, DNA-directed RNA polymerase II 14.2 kDa polypeptide, ... | 著者 | Westover, K.D, Bushnell, D.A, Kornberg, R.D. | 登録日 | 2004-02-20 | 公開日 | 2004-03-02 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (3.61 Å) | 主引用文献 | Structural Basis of Transcription: Separation of RNA from DNA by RNA Polymerase II Science, 303, 2004
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7NV0
| Human Pol Kappa holoenzyme with wt PCNA | 分子名称: | DNA Primer, DNA Template, DNA polymerase kappa, ... | 著者 | Lancey, C, De Biasio, A, Hamdan, S.M. | 登録日 | 2021-03-15 | 公開日 | 2021-11-10 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Cryo-EM structure of human Pol kappa bound to DNA and mono-ubiquitylated PCNA. Nat Commun, 12, 2021
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7QHS
| S. cerevisiae CMGE nucleating origin DNA melting | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 45, ... | 著者 | Lewis, J.S, Sousa, J.S, Costa, A. | 登録日 | 2021-12-14 | 公開日 | 2022-06-15 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Mechanism of replication origin melting nucleated by CMG helicase assembly. Nature, 606, 2022
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2WTY
| Crystal structure of the homodimeric MafB in complex with the T-MARE binding site | 分子名称: | DNA (5'-D(*TP*AP*AP*TP*TP*GP*CP*TP*GP*AP*CP*TP*CP*AP *GP*CP*AP*AP*AP*T)-3'), DNA (5'-D(*TP*AP*TP*TP*TP*GP*CP*TP*GP*AP*GP*TP*CP*AP *GP*CP*AP*AP*TP*T)-3'), MAGNESIUM ION, ... | 著者 | Consani Textor, L, Holton, S, Wilmanns, M. | 登録日 | 2009-09-25 | 公開日 | 2010-12-08 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Design of a bZIP Transcription Factor with Homo/Heterodimer-Induced DNA-Binding Preference. Structure, 22, 2014
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8HIG
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3IV5
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3JR9
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6N1R
| Tetrahedral oligomeric complex of GyrA N-terminal fragment, solved by cryoEM in tetrahedral symmetry | 分子名称: | DNA gyrase subunit A | 著者 | Soczek, K.M, Grant, T, Rosenthal, P.B, Mondragon, A. | 登録日 | 2018-11-10 | 公開日 | 2018-12-05 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | CryoEM structures of open dimers of Gyrase A in complex with DNA illuminate mechanism of strand passage. Elife, 7, 2018
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6N1Q
| Dihedral oligomeric complex of GyrA N-terminal fragment, solved by cryoEM in D2 symmetry | 分子名称: | DNA gyrase subunit A | 著者 | Soczek, K.M, Grant, T, Rosenthal, P.B, Mondragon, A. | 登録日 | 2018-11-10 | 公開日 | 2018-12-05 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (5.16 Å) | 主引用文献 | CryoEM structures of open dimers of Gyrase A in complex with DNA illuminate mechanism of strand passage. Elife, 7, 2018
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8D86
| Isoreticular, interpenetrating co-crystal of Replication Initiator Protein REPE54 and symmetrical expanded duplex (31mer) containing the cognate REPE54 sequence and an additional G-C rich sequence co-crystallized with a guest small molecule, netropsin. | 分子名称: | DNA (5'-D(A*CP*CP*CP*GP*GP*AP*CP*CP*TP*GP*TP*GP*AP*CP*AP*AP*AP*TP*TP*GP*CP*CP*CP*TP*CP*AP*GP*AP*CP*GP*G)-3'), DNA (5'-D(A*GP*GP*CP*CP*GP*TP*CP*TP*GP*AP*GP*GP*GP*CP*AP*AP*TP*TP*TP*GP*TP*CP*AP*CP*AP*GP*GP*TP*CP*CP*G)-3'), MAGNESIUM ION, ... | 著者 | Orun, A.R, Snow, C.D. | 登録日 | 2022-06-07 | 公開日 | 2023-06-28 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3.12 Å) | 主引用文献 | Modular Protein-DNA Cocrystals as Precise, Programmable Assembly Scaffolds. Acs Nano, 17, 2023
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7U50
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9BH8
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3A2F
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7SPM
| Replication Initiator Protein REPE54 and cognate DNA sequence with terminal three prime phosphates chemically crosslinked (30 mg/mL EDC, 12 hours, 2 doses). | 分子名称: | DNA (5'-D(*CP*CP*TP*GP*TP*GP*AP*CP*AP*AP*AP*TP*TP*GP*CP*CP*CP*TP*CP*AP*GP*A)-3'), DNA (5'-D(*CP*TP*GP*AP*GP*GP*GP*CP*AP*AP*TP*TP*TP*GP*TP*CP*AP*CP*AP*GP*GP*A)-3'), MAGNESIUM ION, ... | 著者 | Ward, A.R, Snow, C.D. | 登録日 | 2021-11-02 | 公開日 | 2021-11-10 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3.28 Å) | 主引用文献 | Stabilizing DNA-Protein Co-Crystals via Intra-Crystal Chemical Ligation of the DNA Crystals, 12, 2022
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1YSE
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4HF2
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4HF1
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6XN9
| Solution NMR structure of recifin, a cysteine-rich tyrosyl-DNA Phosphodiesterase I modulatory peptide from the marine sponge Axinella sp. | 分子名称: | Recifin modulatory peptide | 著者 | Schroeder, C.I, Rosengren, K.J, O'Keefe, B.R. | 登録日 | 2020-07-02 | 公開日 | 2021-02-10 | 実験手法 | SOLUTION NMR | 主引用文献 | Recifin A, Initial Example of the Tyr-Lock Peptide Structural Family, Is a Selective Allosteric Inhibitor of Tyrosyl-DNA Phosphodiesterase I. J.Am.Chem.Soc., 142, 2020
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6LZJ
| Aquifex aeolicus MutL ATPase domain complexed with AMPPCP | 分子名称: | DNA mismatch repair protein MutL, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER | 著者 | Fukui, K, Izuhara, K, Yano, T. | 登録日 | 2020-02-19 | 公開日 | 2020-07-01 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.72835565 Å) | 主引用文献 | A Lynch syndrome-associated mutation at a Bergerat ATP-binding fold destabilizes the structure of the DNA mismatch repair endonuclease MutL. J.Biol.Chem., 295, 2020
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