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7U6K
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BU of 7u6k by Molmil
Isoreticular, interpenetrating co-crystal of Replication Initiator Protein REPE54 and symmetrical expanded duplex (31mer) containing the cognate REPE54 sequence and an additional G-C rich sequence.
分子名称: DNA (5'-D(A*CP*CP*CP*GP*GP*AP*CP*CP*TP*GP*TP*GP*AP*CP*AP*AP*AP*TP*TP*GP*CP*CP*CP*TP*CP*AP*GP*AP*CP*GP*G)-3'), DNA (5'-D(A*GP*GP*CP*CP*GP*TP*CP*TP*GP*AP*GP*GP*GP*CP*AP*AP*TP*TP*TP*GP*TP*CP*AP*CP*AP*GP*GP*TP*CP*CP*G)-3'), MAGNESIUM ION, ...
著者Ward, A.R, Snow, C.D.
登録日2022-03-04
公開日2023-03-29
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Modular Protein-DNA Cocrystals as Precise, Programmable Assembly Scaffolds.
Acs Nano, 17, 2023
5VVR
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BU of 5vvr by Molmil
Ternary complex of RNA Pol II, transcription scaffold and Rad26
分子名称: DNA (NTS), DNA (TS), DNA repair and recombination protein RAD26, ...
著者Lahiri, I, Leschziner, A.E.
登録日2017-05-19
公開日2017-11-22
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (5.8 Å)
主引用文献Structural basis for the initiation of eukaryotic transcription-coupled DNA repair.
Nature, 551, 2017
4RKH
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BU of 4rkh by Molmil
Structure of the MSL2 CXC domain bound with a specific MRE sequence
分子名称: DNA (5'-D(*AP*TP*CP*CP*AP*TP*CP*TP*CP*GP*CP*TP*CP*AP*T)-3'), DNA (5'-D(*AP*TP*GP*AP*GP*CP*GP*AP*GP*AP*TP*GP*GP*AP*T)-3'), E3 ubiquitin-protein ligase msl-2, ...
著者Zheng, S, Ye, K.
登録日2014-10-13
公開日2015-01-21
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis of X chromosome DNA recognition by the MSL2 CXC domain during Drosophila dosage compensation.
Genes Dev., 28, 2014
4U7B
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BU of 4u7b by Molmil
Crystal structure of a pre-cleavage Mos1 transpososome
分子名称: DNA (25-MER), DNA (31-MER), Mariner Mos1 transposase, ...
著者Richardson, J.M.
登録日2014-07-30
公開日2015-02-11
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.09 Å)
主引用文献Structural role of the flanking DNA in mariner transposon excision.
Nucleic Acids Res., 43, 2015
5VVS
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BU of 5vvs by Molmil
RNA pol II elongation complex
分子名称: DNA (NTS), DNA (TS), DNA-directed RNA polymerase II subunit RPB1, ...
著者Lahiri, I, Leschziner, A.E.
登録日2017-05-20
公開日2017-11-22
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (6.4 Å)
主引用文献Structural basis for the initiation of eukaryotic transcription-coupled DNA repair.
Nature, 551, 2017
8BOT
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BU of 8bot by Molmil
Cryo-EM structure of NHEJ supercomplex(trimer)
分子名称: DNA (24-MER), DNA (27-MER), DNA (28-MER), ...
著者Hardwick, S.W, Chaplin, A.K.
登録日2022-11-15
公開日2023-06-28
最終更新日2023-08-16
実験手法ELECTRON MICROSCOPY (7.76 Å)
主引用文献Cryo-EM structure of a DNA-PK trimer: higher order oligomerisation in NHEJ.
Structure, 31, 2023
1SFO
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BU of 1sfo by Molmil
RNA POLYMERASE II STRAND SEPARATED ELONGATION COMPLEX
分子名称: DNA STRAND, DNA-directed RNA polymerase II 13.6 kDa polypeptide, DNA-directed RNA polymerase II 14.2 kDa polypeptide, ...
著者Westover, K.D, Bushnell, D.A, Kornberg, R.D.
登録日2004-02-20
公開日2004-03-02
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3.61 Å)
主引用文献Structural Basis of Transcription: Separation of RNA from DNA by RNA Polymerase II
Science, 303, 2004
7NV0
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BU of 7nv0 by Molmil
Human Pol Kappa holoenzyme with wt PCNA
分子名称: DNA Primer, DNA Template, DNA polymerase kappa, ...
著者Lancey, C, De Biasio, A, Hamdan, S.M.
登録日2021-03-15
公開日2021-11-10
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Cryo-EM structure of human Pol kappa bound to DNA and mono-ubiquitylated PCNA.
Nat Commun, 12, 2021
7QHS
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BU of 7qhs by Molmil
S. cerevisiae CMGE nucleating origin DNA melting
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 45, ...
著者Lewis, J.S, Sousa, J.S, Costa, A.
登録日2021-12-14
公開日2022-06-15
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Mechanism of replication origin melting nucleated by CMG helicase assembly.
Nature, 606, 2022
2WTY
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BU of 2wty by Molmil
Crystal structure of the homodimeric MafB in complex with the T-MARE binding site
分子名称: DNA (5'-D(*TP*AP*AP*TP*TP*GP*CP*TP*GP*AP*CP*TP*CP*AP *GP*CP*AP*AP*AP*T)-3'), DNA (5'-D(*TP*AP*TP*TP*TP*GP*CP*TP*GP*AP*GP*TP*CP*AP *GP*CP*AP*AP*TP*T)-3'), MAGNESIUM ION, ...
著者Consani Textor, L, Holton, S, Wilmanns, M.
登録日2009-09-25
公開日2010-12-08
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Design of a bZIP Transcription Factor with Homo/Heterodimer-Induced DNA-Binding Preference.
Structure, 22, 2014
8HIG
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BU of 8hig by Molmil
Co-crystal structure of C-terminal DNA binding domain of Saccharopolyspora erythraea GlnR in complex with its cognate promoter DNA
分子名称: DNA (5'-D(*AP*CP*GP*TP*AP*AP*CP*AP*TP*CP*GP*CP*GP*GP*TP*AP*AP*CP*AP*C)-3'), DNA (5'-D(*GP*TP*GP*TP*TP*AP*CP*CP*GP*CP*GP*AP*TP*GP*TP*TP*AP*CP*GP*T)-3'), DNA-binding response OmpR family regulator
著者Lin, W, Xu, J.C, Zhang, Y.
登録日2022-11-20
公開日2023-11-22
実験手法X-RAY DIFFRACTION (2.329 Å)
主引用文献Co-crystal structure of C-terminal DNA binding domain of Saccharopolyspora erythraea GlnR in complex with its cognate promoter DNA
To Be Published
3IV5
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BU of 3iv5 by Molmil
Crystal structure of Fis bound to 27 bp optimal binding sequence F1
分子名称: DNA (27-MER), DNA-binding protein fis
著者Stella, S, Cascio, D, Johnson, R.C.
登録日2009-08-31
公開日2010-04-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献The shape of the DNA minor groove directs binding by the DNA-bending protein Fis.
Genes Dev., 24, 2010
3JR9
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BU of 3jr9 by Molmil
Crystal structure of Fis bound to 27 bp optimal binding sequence F2
分子名称: DNA (27-MER), DNA-binding protein fis
著者Stella, S, Cascio, D, Johnson, R.C.
登録日2009-09-08
公開日2010-04-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献The shape of the DNA minor groove directs binding by the DNA-bending protein Fis.
Genes Dev., 24, 2010
6N1R
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BU of 6n1r by Molmil
Tetrahedral oligomeric complex of GyrA N-terminal fragment, solved by cryoEM in tetrahedral symmetry
分子名称: DNA gyrase subunit A
著者Soczek, K.M, Grant, T, Rosenthal, P.B, Mondragon, A.
登録日2018-11-10
公開日2018-12-05
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献CryoEM structures of open dimers of Gyrase A in complex with DNA illuminate mechanism of strand passage.
Elife, 7, 2018
6N1Q
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BU of 6n1q by Molmil
Dihedral oligomeric complex of GyrA N-terminal fragment, solved by cryoEM in D2 symmetry
分子名称: DNA gyrase subunit A
著者Soczek, K.M, Grant, T, Rosenthal, P.B, Mondragon, A.
登録日2018-11-10
公開日2018-12-05
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (5.16 Å)
主引用文献CryoEM structures of open dimers of Gyrase A in complex with DNA illuminate mechanism of strand passage.
Elife, 7, 2018
8D86
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BU of 8d86 by Molmil
Isoreticular, interpenetrating co-crystal of Replication Initiator Protein REPE54 and symmetrical expanded duplex (31mer) containing the cognate REPE54 sequence and an additional G-C rich sequence co-crystallized with a guest small molecule, netropsin.
分子名称: DNA (5'-D(A*CP*CP*CP*GP*GP*AP*CP*CP*TP*GP*TP*GP*AP*CP*AP*AP*AP*TP*TP*GP*CP*CP*CP*TP*CP*AP*GP*AP*CP*GP*G)-3'), DNA (5'-D(A*GP*GP*CP*CP*GP*TP*CP*TP*GP*AP*GP*GP*GP*CP*AP*AP*TP*TP*TP*GP*TP*CP*AP*CP*AP*GP*GP*TP*CP*CP*G)-3'), MAGNESIUM ION, ...
著者Orun, A.R, Snow, C.D.
登録日2022-06-07
公開日2023-06-28
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.12 Å)
主引用文献Modular Protein-DNA Cocrystals as Precise, Programmable Assembly Scaffolds.
Acs Nano, 17, 2023
7U50
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BU of 7u50 by Molmil
APE1 bound to a nucleosome core particle with AP-site at SHL-6
分子名称: DNA (144-MER), DNA (145-MER), DNA-(apurinic or apyrimidinic site) endonuclease, ...
著者Weaver, T.M, Freudenthal, B.D.
登録日2022-03-01
公開日2022-09-07
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural basis for APE1 processing DNA damage in the nucleosome.
Nat Commun, 13, 2022
9BH8
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BU of 9bh8 by Molmil
Human DNA polymerase theta helicase domain dimer bound to DNA in the microhomology searching conformation
分子名称: DNA polymerase theta, Stem-loop DNA with microhomology in the 3' overhang
著者Zerio, C.J, Lander, G.C.
登録日2024-04-19
公開日2024-05-01
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Human polymerase theta helicase positions DNA microhomologies for double-strand break repair
To Be Published
3A2F
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BU of 3a2f by Molmil
Crystal Structure of Pyrococcus furiosus DNA polymerase/PCNA monomer mutant complex
分子名称: DNA polymerase, DNA polymerase sliding clamp
著者Nishida, H, Ishino, Y, Morikawa, K.
登録日2009-05-15
公開日2009-11-03
最終更新日2021-11-10
実験手法X-RAY DIFFRACTION (2.67 Å)
主引用文献Structural determinant for switching between the polymerase and exonuclease modes in the PCNA-replicative DNA polymerase complex
To be Published
7SPM
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BU of 7spm by Molmil
Replication Initiator Protein REPE54 and cognate DNA sequence with terminal three prime phosphates chemically crosslinked (30 mg/mL EDC, 12 hours, 2 doses).
分子名称: DNA (5'-D(*CP*CP*TP*GP*TP*GP*AP*CP*AP*AP*AP*TP*TP*GP*CP*CP*CP*TP*CP*AP*GP*A)-3'), DNA (5'-D(*CP*TP*GP*AP*GP*GP*GP*CP*AP*AP*TP*TP*TP*GP*TP*CP*AP*CP*AP*GP*GP*A)-3'), MAGNESIUM ION, ...
著者Ward, A.R, Snow, C.D.
登録日2021-11-02
公開日2021-11-10
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.28 Å)
主引用文献Stabilizing DNA-Protein Co-Crystals via Intra-Crystal Chemical Ligation of the DNA
Crystals, 12, 2022
1YSE
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BU of 1yse by Molmil
Solution structure of the MAR-binding domain of SATB1
分子名称: DNA-binding protein SATB1
著者Yamasaki, K, Yamaguchi, H.
登録日2005-02-08
公開日2006-01-03
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution Structure and DNA-binding Mode of the Matrix Attachment Region-binding Domain of the Transcription Factor SATB1 That Regulates the T-cell Maturation
J.Biol.Chem., 281, 2006
4HF2
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BU of 4hf2 by Molmil
Crystal Structure of E43A IscR mutant bound to its promoter
分子名称: DNA (29-MER), HTH-type transcriptional regulator IscR
著者Rajagopalan, S.R, Phillips, K.J.
登録日2012-10-04
公開日2013-05-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.99 Å)
主引用文献Studies of IscR reveal a unique mechanism for metal-dependent regulation of DNA binding specificity.
Nat.Struct.Mol.Biol., 20, 2013
4HF1
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BU of 4hf1 by Molmil
Crystal Structure of IscR bound to its promoter
分子名称: DNA (29-MER), HTH-type transcriptional regulator IscR
著者Rajagopalan, S.R, Phillips, K.J.
登録日2012-10-04
公開日2013-05-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.222 Å)
主引用文献Studies of IscR reveal a unique mechanism for metal-dependent regulation of DNA binding specificity.
Nat.Struct.Mol.Biol., 20, 2013
6XN9
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BU of 6xn9 by Molmil
Solution NMR structure of recifin, a cysteine-rich tyrosyl-DNA Phosphodiesterase I modulatory peptide from the marine sponge Axinella sp.
分子名称: Recifin modulatory peptide
著者Schroeder, C.I, Rosengren, K.J, O'Keefe, B.R.
登録日2020-07-02
公開日2021-02-10
実験手法SOLUTION NMR
主引用文献Recifin A, Initial Example of the Tyr-Lock Peptide Structural Family, Is a Selective Allosteric Inhibitor of Tyrosyl-DNA Phosphodiesterase I.
J.Am.Chem.Soc., 142, 2020
6LZJ
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BU of 6lzj by Molmil
Aquifex aeolicus MutL ATPase domain complexed with AMPPCP
分子名称: DNA mismatch repair protein MutL, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER
著者Fukui, K, Izuhara, K, Yano, T.
登録日2020-02-19
公開日2020-07-01
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.72835565 Å)
主引用文献A Lynch syndrome-associated mutation at a Bergerat ATP-binding fold destabilizes the structure of the DNA mismatch repair endonuclease MutL.
J.Biol.Chem., 295, 2020

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件を2024-08-28に公開中

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