3T03
| Crystal structure of PPAR gamma ligand binding domain in complex with a novel partial agonist GQ-16 | Descriptor: | (5Z)-5-(5-bromo-2-methoxybenzylidene)-3-(4-methylbenzyl)-1,3-thiazolidine-2,4-dione, Nuclear receptor coactivator 1, Peroxisome proliferator-activated receptor gamma | Authors: | Rajagopalan, S, Webb, P, Baxter, J.D, Brennan, R.G, Phillips, K.J. | Deposit date: | 2011-07-19 | Release date: | 2012-05-23 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | GQ-16, a novel peroxisome proliferator-activated receptor (PPAR gamma) ligand, promotes insulin sensitization without weight gain. J.Biol.Chem., 287, 2012
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4HF0
| Crystal Structure of Apo IscR | Descriptor: | HTH-type transcriptional regulator IscR, SULFATE ION | Authors: | Rajagopalan, S.R, Phillips, K.J. | Deposit date: | 2012-10-04 | Release date: | 2013-05-08 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Studies of IscR reveal a unique mechanism for metal-dependent regulation of DNA binding specificity. Nat.Struct.Mol.Biol., 20, 2013
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4HF2
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4HF1
| Crystal Structure of IscR bound to its promoter | Descriptor: | DNA (29-MER), HTH-type transcriptional regulator IscR | Authors: | Rajagopalan, S.R, Phillips, K.J. | Deposit date: | 2012-10-04 | Release date: | 2013-05-08 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.222 Å) | Cite: | Studies of IscR reveal a unique mechanism for metal-dependent regulation of DNA binding specificity. Nat.Struct.Mol.Biol., 20, 2013
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4NQA
| Crystal structure of liganded hRXR-alpha/hLXR-beta heterodimer on DNA | Descriptor: | (9cis)-retinoic acid, 5'-D(*TP*AP*AP*GP*GP*TP*CP*AP*CP*TP*TP*CP*AP*GP*GP*TP*CP*A)-3', 5'-D(*TP*AP*TP*GP*AP*CP*CP*TP*GP*AP*AP*GP*TP*GP*AP*CP*CP*T)-3', ... | Authors: | Lou, X.H, Toresson, G, Benod, C, Suh, J.H, Phillips, K.J, Webb, P, Gustafsson, J.A. | Deposit date: | 2013-11-24 | Release date: | 2014-02-26 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.102 Å) | Cite: | Structure of the retinoid X receptor alpha-liver X receptor beta (RXR alpha-LXR beta ) heterodimer on DNA. Nat.Struct.Mol.Biol., 21, 2014
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