4HF2
Crystal Structure of E43A IscR mutant bound to its promoter
Summary for 4HF2
| Entry DOI | 10.2210/pdb4hf2/pdb |
| Related | 4HF0 4HF1 |
| Descriptor | HTH-type transcriptional regulator IscR, DNA (29-MER) (3 entities in total) |
| Functional Keywords | whth, protein-dna complex, iron-sulfur cluster, winged helix-turn-helix, transcriptional regulator, redox sensor, dna binding, transcription-dna complex, transcription/dna |
| Biological source | Escherichia coli More |
| Total number of polymer chains | 4 |
| Total formula weight | 54117.20 |
| Authors | Rajagopalan, S.R.,Phillips, K.J. (deposition date: 2012-10-04, release date: 2013-05-08, Last modification date: 2024-02-28) |
| Primary citation | Rajagopalan, S.,Teter, S.J.,Zwart, P.H.,Brennan, R.G.,Phillips, K.J.,Kiley, P.J. Studies of IscR reveal a unique mechanism for metal-dependent regulation of DNA binding specificity. Nat.Struct.Mol.Biol., 20:740-747, 2013 Cited by PubMed: 23644595DOI: 10.1038/nsmb.2568 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.99 Å) |
Structure validation
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