4NQA
Crystal structure of liganded hRXR-alpha/hLXR-beta heterodimer on DNA
Summary for 4NQA
Entry DOI | 10.2210/pdb4nqa/pdb |
Descriptor | Retinoic acid receptor RXR-alpha, Liver X nuclear receptor beta, Nuclear receptor coactivator 2, ... (8 entities in total) |
Functional Keywords | multi-domain, rxr, lxr, dbd, lbd, ligand, zinc finger, transcription regulator-dna complex, transcription regulator/dna |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus : P19793 F1D8P7 Q15596 |
Total number of polymer chains | 12 |
Total formula weight | 201035.72 |
Authors | Lou, X.H.,Toresson, G.,Benod, C.,Suh, J.H.,Phillips, K.J.,Webb, P.,Gustafsson, J.A. (deposition date: 2013-11-24, release date: 2014-02-26, Last modification date: 2024-02-28) |
Primary citation | Lou, X.,Toresson, G.,Benod, C.,Suh, J.H.,Philips, K.J.,Webb, P.,Gustafsson, J.A. Structure of the retinoid X receptor alpha-liver X receptor beta (RXR alpha-LXR beta ) heterodimer on DNA. Nat.Struct.Mol.Biol., 21:277-281, 2014 Cited by PubMed: 24561505DOI: 10.1038/nsmb.2778 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.102 Å) |
Structure validation
Download full validation report