4NQA

Crystal structure of liganded hRXR-alpha/hLXR-beta heterodimer on DNA

Summary for 4NQA

• Entry DOI: 10.2210/pdb4nqa/pdb
• Descriptor: Retinoic acid receptor RXR-alpha, Liver X nuclear receptor beta, Nuclear receptor coactivator 2, ... (8 entities in total)
• Functional Keywords: multi-domain, rxr, lxr, dbd, lbd, ligand, zinc finger, transcription regulator-dna complex, transcription regulator/dna
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus : P19793 F1D8P7 Q15596
• Total number of polymer chains: 12
• Total formula weight: 201035.72

Authors

Lou, X.H.,Toresson, G.,Benod, C.,Suh, J.H.,Phillips, K.J.,Webb, P.,Gustafsson, J.A. (deposition date: 2013-11-24, release date: 2014-02-26, Last modification date: 2024-02-28)

• Primary citation: Lou, X.,Toresson, G.,Benod, C.,Suh, J.H.,Philips, K.J.,Webb, P.,Gustafsson, J.A.; Structure of the retinoid X receptor alpha-liver X receptor beta (RXR alpha-LXR beta ) heterodimer on DNA.; Nat.Struct.Mol.Biol., 21:277-281, 2014; PubMed: 24561505; DOI: 10.1038/nsmb.2778

Experimental method

X-RAY DIFFRACTION (3.102 Å)