2WTY

Crystal structure of the homodimeric MafB in complex with the T-MARE binding site

Summary for 2WTY

• Entry DOI: 10.2210/pdb2wty/pdb
• Related: 2WT7
• Descriptor: TRANSCRIPTION FACTOR MAFB, DNA (5'-D(*TP*AP*AP*TP*TP*GP*CP*TP*GP*AP*CP*TP*CP*AP *GP*CP*AP*AP*AP*T)-3'), DNA (5'-D(*TP*AP*TP*TP*TP*GP*CP*TP*GP*AP*GP*TP*CP*AP *GP*CP*AP*AP*TP*T)-3'), ... (5 entities in total)
• Functional Keywords: repressor, dna-binding, transcription, proto-oncogene, transcription regulation, tumor suppressor, dna, b-zip, nucleus, activator, ap-1 binding site, protein-dna complex
• Biological source: MUS MUSCULUS (HOUSE MOUSE)
• Cellular location: Nucleus: P54841
• Total number of polymer chains: 4
• Total formula weight: 35675.18

Authors

Consani Textor, L.,Holton, S.,Wilmanns, M. (deposition date: 2009-09-25, release date: 2010-12-08, Last modification date: 2014-03-19)

• Primary citation: Pogenberg, V.,Consani Textor, L.,Vanhille, L.,Holton, S.J.,Sieweke, M.H.,Wilmanns, M.; Design of a bZIP Transcription Factor with Homo/Heterodimer-Induced DNA-Binding Preference.; Structure, 22:466-, 2014; PubMed: 24530283; DOI: 10.1016/J.STR.2013.12.017

Experimental method

X-RAY DIFFRACTION (2.9 Å)