2WT7

Crystal structure of the bZIP heterodimeric complex MafB:cFos bound to DNA

Summary for 2WT7

Entry DOI	10.2210/pdb2wt7/pdb
Descriptor	PROTO-ONCOGENE PROTEIN C-FOS, TRANSCRIPTION FACTOR MAFB, MODIFIED T-MARE MOTIF, ... (6 entities in total)
Functional Keywords	transcription, transcription regulation, nucleus, activator, repressor, dna-binding, phosphoprotein, differentiation, tumor suppressor, proliferation, proto-oncogene
Biological source	MUS MUSCULUS (HOUSE MOUSE) More
Total number of polymer chains	4
Total formula weight	28329.59
Authors	Pogenberg, V.,Holton, S.,Wilmanns, M. (deposition date: 2009-09-11, release date: 2010-09-29, Last modification date: 2024-05-08)
Primary citation	Pogenberg, V.,Consani Textor, L.,Vanhille, L.,Holton, S.J.,Sieweke, M.H.,Wilmanns, M. Design of a bZIP Transcription Factor with Homo/Heterodimer-Induced DNA-Binding Preference. Structure, 22:466-, 2014 Cited by PubMed: 24530283 DOI: 10.1016/J.STR.2013.12.017 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation