2WT7
Crystal structure of the bZIP heterodimeric complex MafB:cFos bound to DNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | PROTO-ONCOGENE PROTEIN C-FOS | polymer | 63 | 7524.6 | 1 | UniProt (P01101) Pfam (PF00170) | MUS MUSCULUS (HOUSE MOUSE) | CFOS, CELLULAR ONCOGENE FOS |
| 2 | B (B) | TRANSCRIPTION FACTOR MAFB | polymer | 90 | 10915.6 | 1 | UniProt (P54841) Pfam (PF03131) | MUS MUSCULUS (HOUSE MOUSE) | MAFB, MAF-B, V-MAF MUSCULOAPONEUROTIC FIBROSARCOMA ONCOGENE HOMOLOG B, TRANSCRIPTION FACTOR MAF-1, SEGMENTATION PROTEIN KR, KREISLER |
| 3 | C (C) | MODIFIED T-MARE MOTIF | polymer | 16 | 4897.2 | 1 | SYNTHETIC CONSTRUCT | ||
| 4 | D (D) | MODIFIED T-MARE MOTIF | polymer | 16 | 4897.2 | 1 | SYNTHETIC CONSTRUCT | ||
| 5 | E (C) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 6 | F, G, H, I (A, B, C, D) | water | water | 18.0 | 172 | Chemie (HOH) |
Sequence modifications
B: 214 - 303 (UniProt: P54841)
| PDB | External Database | Details |
|---|---|---|
| Ser 298 | Cys 298 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 28234.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 95.0 | |
| All* | Total formula weight | 28329.6 |
