2WTY
Crystal structure of the homodimeric MafB in complex with the T-MARE binding site
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | TRANSCRIPTION FACTOR MAFB | polymer | 97 | 11697.4 | 2 | UniProt (P54841) Pfam (PF03131) In PDB | MUS MUSCULUS (HOUSE MOUSE) | V-MAF MUSCULOAPONEUROTIC FIBROSARCOMA ONCOGENE HOMOLOG B, TRANSCRIPTION FACTOR MAF-1, SEGMENTATION PROTEIN KR, KREISLER, MAF-B |
| 2 | C | DNA (5'-D(*TP*AP*AP*TP*TP*GP*CP*TP*GP*AP*CP*TP*CP*AP *GP*CP*AP*AP*AP*T)-3') | polymer | 20 | 6117.0 | 1 | T-MARE BINDING SITE | ||
| 3 | D | DNA (5'-D(*TP*AP*TP*TP*TP*GP*CP*TP*GP*AP*GP*TP*CP*AP *GP*CP*AP*AP*TP*T)-3') | polymer | 20 | 6139.0 | 1 | T-MARE BINDING SITE | ||
| 4 | D | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 5 | water | water | 18.0 | 71 | Chemie (HOH) |
Sequence modifications
A, B: 211 - 306 (UniProt: P54841)
| PDB | External Database | Details |
|---|---|---|
| Met 210 | - | expression tag |
| Ser 298 | Cys 298 | engineered mutation |
| Arg 306 | Phe 306 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 35650.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 24.3 | |
| All* | Total formula weight | 35675.2 |
