7NV0

Human Pol Kappa holoenzyme with wt PCNA

Summary for 7NV0

• Entry DOI: 10.2210/pdb7nv0/pdb
• Related: 7NV1
• EMDB information: 12601 12602
• Descriptor: DNA polymerase kappa, Proliferating cell nuclear antigen, DNA Primer, ... (5 entities in total)
• Functional Keywords: translesion synthesis, tls, replication
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 6
• Total formula weight: 206042.57

Authors

Lancey, C.,De Biasio, A.,Hamdan, S.M. (deposition date: 2021-03-15, release date: 2021-11-10, Last modification date: 2024-07-10)

• Primary citation: Lancey, C.,Tehseen, M.,Bakshi, S.,Percival, M.,Takahashi, M.,Sobhy, M.A.,Raducanu, V.S.,Blair, K.,Muskett, F.W.,Ragan, T.J.,Crehuet, R.,Hamdan, S.M.,De Biasio, A.; Cryo-EM structure of human Pol kappa bound to DNA and mono-ubiquitylated PCNA.; Nat Commun, 12:6095-6095, 2021; PubMed: 34667155; DOI: 10.1038/s41467-021-26251-6

Experimental method

ELECTRON MICROSCOPY (3.4 Å)