PDB: 9760 件ウェブページステータス検索Chemie searchBIRD

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7RD3	Crystal structure of PfCSP peptide 21 with vaccine-elicited human anti-malaria antibody m42.126 分子名称: Circumsporozoite protein, antibody m42.126 heavy chain, antibody m42.126 light chain 著者 Xu, K, Kwong, P.D. 登録日 2021-07-09 公開日 2021-12-15 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 Vaccination in a humanized mouse model elicits highly protective PfCSP-targeting anti-malarial antibodies. Immunity, 54, 2021
7RCS	Crystal structure of PfCSP peptide 21 with vaccine-elicited human anti-malaria antibody m43.160 分子名称: Circumsporozoite protein, antibody m43.160 heavy chain, antibody m43.160 light chain 著者 Xu, K, Kwong, P.D. 登録日 2021-07-08 公開日 2021-12-15 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Vaccination in a humanized mouse model elicits highly protective PfCSP-targeting anti-malarial antibodies. Immunity, 54, 2021
7RD4	Crystal structure of PfCSP peptide 21 with vaccine-elicited human anti-malaria antibody m43.149 分子名称: Circumsporozoite protein, antibody m43.149 heavy chain, antibody m43.149 light chain 著者 Xu, K, Kwong, P.D. 登録日 2021-07-09 公開日 2021-12-15 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Vaccination in a humanized mouse model elicits highly protective PfCSP-targeting anti-malarial antibodies. Immunity, 54, 2021
7CJF	Crystal structure of SARS-CoV-2 RBD in complex with a neutralizing antibody Fab 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, antibody heavy chain, ... 著者 Guo, Y, Li, X, Zhang, G, Fu, D, Schweizer, L, Zhang, H, Rao, Z. 登録日 2020-07-10 公開日 2020-11-11 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.108 Å) 主引用文献 A SARS-CoV-2 neutralizing antibody with extensive Spike binding coverage and modified for optimal therapeutic outcomes. Nat Commun, 12, 2021
3CFJ	Crystal structure of catalytic elimination antibody 34E4, orthorhombic crystal form 分子名称: CATALYTIC ANTIBODY FAB 34E4 HEAVY CHAIN fusion, CATALYTIC ANTIBODY FAB 34E4 LIGHT CHAIN fusion, GLYCEROL, ... 著者 Debler, E.W, Wilson, I.A. 登録日 2008-03-04 公開日 2008-04-15 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Conformational isomerism can limit antibody catalysis. J.Biol.Chem., 283, 2008
7M42	Complex of SARS-CoV-2 receptor binding domain with the Fab fragments of neutralizing antibodies REGN10985 and REGN10989 分子名称: REGN10985 antibody Fab fragment heavy chain, REGN10985 antibody Fab fragment light chain, REGN10989 antibody Fab fragment heavy chain, ... 著者 Zhou, Y, Romero Hernandez, A, Saotome, K, Franklin, M.C. 登録日 2021-03-19 公開日 2021-07-28 最終更新日 2021-08-25 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 The monoclonal antibody combination REGEN-COV protects against SARS-CoV-2 mutational escape in preclinical and human studies. Cell, 184, 2021
7MXP	Cryo-EM structure of NTD-directed neutralizing antibody LP5 Fab in complex with SARS-CoV-2 S2P spike 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)][beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Reddem, E.R, Casner, R.G, Shapiro, L. 登録日 2021-05-19 公開日 2022-05-25 最終更新日 2022-12-21 実験手法 ELECTRON MICROSCOPY (4.46 Å) 主引用文献 Antibody screening at reduced pH enables preferential selection of potently neutralizing antibodies targeting SARS-CoV-2. Aiche J, 67, 2021
3CFK	Crystal structure of catalytic elimination antibody 34E4, triclinic crystal form 分子名称: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CADMIUM ION, CATALYTIC ANTIBODY FAB 34E4 HEAVY CHAIN,Uncharacterized protein, ... 著者 Debler, E.W, Wilson, I.A. 登録日 2008-03-04 公開日 2008-04-15 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Conformational isomerism can limit antibody catalysis. J.Biol.Chem., 283, 2008
8D5C	anti-HIV-1 gp120-sCD4 complex antibody CG10 Fab in complex with B41-sCD4 分子名称: CG10 Fab heavy chain, CG10 Fab light chain, Envelope glycoprotein gp160, ... 著者 Yang, Z, Bjorkman, P.J, Gershoni, J.M. 登録日 2022-06-04 公開日 2022-11-16 最終更新日 2023-01-04 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Antibody Recognition of CD4-Induced Open HIV-1 Env Trimers. J.Virol., 96, 2022
8D54	anti HIV gp120/CD4 complex antibody CG10 Fab 分子名称: CG10 Fab heavy chain, CG10 Fab light chain 著者 Yang, Z, Bjorkman, P.J. 登録日 2022-06-03 公開日 2022-12-14 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Antibody Recognition of CD4-Induced Open HIV-1 Env Trimers. J.Virol., 96, 2022
7YC5	Cryo-EM structure of SARS-CoV-2 spike in complex with K202.B bispecific antibody 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain from K202.B, bispecific antibody, ... 著者 Yoo, Y, Cho, H.S. 登録日 2022-06-30 公開日 2023-07-05 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Novel bispecific human antibody platform specifically targeting a fully open spike conformation potently neutralizes multiple SARS-CoV-2 variants. Antiviral Res., 212, 2023
5N88	Crystal structure of antibody bound to viral protein 分子名称: PC4 and SFRS1-interacting protein, VH59 antibody 著者 Bao, L, Hannon, C, Cruz-Migoni, A, Ptchelkine, D, Sun, M.-y, Derveni, M, Bunjobpol, W, Chambers, J.S, Simmons, A, Phillips, S.E.V, Rabbitts, T.H. 登録日 2017-02-23 公開日 2017-12-20 最終更新日 2019-10-16 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Intracellular immunization against HIV infection with an intracellular antibody that mimics HIV integrase binding to the cellular LEDGF protein. Sci Rep, 7, 2017
5KVF	Zika specific antibody, ZV-64, bound to ZIKA envelope DIII 分子名称: GLYCEROL, ZV-64 Antibody Fab Heavy Chain, ZV-64 Antibody Fab Light Chain, ... 著者 Zhao, H, Nelson, C.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2016-07-14 公開日 2016-08-03 最終更新日 2016-08-24 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Structural Basis of Zika Virus-Specific Antibody Protection. Cell, 166, 2016
5KVD	Zika specific antibody, ZV-2, bound to ZIKA envelope DIII 分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, SODIUM ION, ... 著者 Zhao, H, Nelson, C.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2016-07-14 公開日 2016-08-03 最終更新日 2016-08-24 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Structural Basis of Zika Virus-Specific Antibody Protection. Cell, 166, 2016
8FBW	Crystal structure of SIV-1 V2 antibody NCI05 in complex with a V2 peptide 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CITRIC ACID, DI(HYDROXYETHYL)ETHER, ... 著者 Zhou, T, Kwong, P.D, Van Wazer, D.J. 登録日 2022-11-30 公開日 2023-01-18 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Effect of Passive Administration of Monoclonal Antibodies Recognizing Simian Immunodeficiency Virus (SIV) V2 in CH59-Like Coil/Helical or beta-Sheet Conformations on Time of SIV mac251 Acquisition. J.Virol., 97, 2023
1X9Q	4m5.3 anti-fluorescein single chain antibody fragment (scFv) 分子名称: 2-(6-HYDROXY-3-OXO-3H-XANTHEN-9-YL)-BENZOIC ACID, 4m5.3 anti-fluorescein single chain antibody fragment, ACETATE ION 著者 Midelfort, K.S, Hernandez, H.H, Lippow, S.M, Tidor, B, Drennan, C.L, Wittrup, K.D. 登録日 2004-08-24 公開日 2005-03-22 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Substantial energetic improvement with minimal structural perturbation in a high affinity mutant antibody J.Mol.Biol., 343, 2004
7TBF	Locally refined region of SARS-CoV-2 spike in complex with antibodies B1-182.1 and A19-61.1 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of SARS-CoV-2 antibody A19-61.1, Heavy chain of SARS-CoV-2 antibody B1-182.1, ... 著者 Zhou, T, Tsybovsky, T, Kwong, P.D. 登録日 2021-12-21 公開日 2022-03-30 最終更新日 2022-10-19 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural basis for potent antibody neutralization of SARS-CoV-2 variants including B.1.1.529. Science, 376, 2022
7TCC	Cryo-EM structure of SARS-CoV-2 Omicron spike in complex with antibodies A19-46.1 and B1-182.1 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of antibody A19-46.1, ... 著者 Zhou, T, Kwong, P.D. 登録日 2021-12-23 公開日 2022-03-30 最終更新日 2022-10-19 実験手法 ELECTRON MICROSCOPY (3.86 Å) 主引用文献 Structural basis for potent antibody neutralization of SARS-CoV-2 variants including B.1.1.529. Science, 376, 2022
7CE2	The Crystal structure of TeNT Hc complexed with neutralizing antibody 分子名称: Tetanus toxin, neutralizing antibody heavy chain, neutralizing antibody light chain 著者 Wang, X, Wang, Y, Wu, C, Yu, J, Liao, H. 登録日 2020-06-21 公開日 2021-04-07 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Structural basis of tetanus toxin neutralization by native human monoclonal antibodies. Cell Rep, 35, 2021
1CBV	AN AUTOANTIBODY TO SINGLE-STRANDED DNA: COMPARISON OF THE THREE-DIMENSIONAL STRUCTURES OF THE UNLIGANDED FAB AND A DEOXYNUCLEOTIDE-FAB COMPLEX 分子名称: DNA (5'-D(*TP*TP*T)-3'), PROTEIN (FAB (BV04-01) AUTOANTIBODY-HEAVY CHAIN), PROTEIN (FAB (BV04-01) AUTOANTIBODY-LIGHT CHAIN) 著者 Herron, J.N, He, X.M, Ballard, D.W, Blier, P.R, Pace, P.E, Bothwell, A.L.M, Voss Junior, E.W, Edmundson, A.B. 登録日 1993-03-16 公開日 1994-01-31 最終更新日 2017-11-29 実験手法 X-RAY DIFFRACTION (2.66 Å) 主引用文献 An autoantibody to single-stranded DNA: comparison of the three-dimensional structures of the unliganded Fab and a deoxynucleotide-Fab complex. Proteins, 11, 1991
8C8P	Structure of the SARS-CoV-2 spike glycoprotein in complex with the 10D12 heavy-chain-only antibody (local refinement) 分子名称: Heavy-chain-only antibody 10D12, Spike glycoprotein,SARS-CoV-2 spike glycoprotein 著者 Serna Martin, I, Hurdiss, D.L. 登録日 2023-01-20 公開日 2023-02-22 最終更新日 2023-03-22 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Avidity engineering of human heavy-chain-only antibodies mitigates neutralization resistance of SARS-CoV-2 variants. Front Immunol, 14, 2023
6APO	Anti-Marburgvirus Nucleoprotein Single Domain Antibody A 分子名称: Anti-Marburgvirus Nucleoprotein Single Domain Antibody A 著者 Taylor, A.B, Garza, J.A. 登録日 2017-08-17 公開日 2017-10-11 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.168 Å) 主引用文献 Unveiling a Drift Resistant Cryptotope withinMarburgvirusNucleoprotein Recognized by Llama Single-Domain Antibodies. Front Immunol, 8, 2017
1UWG	Molecular Mechanism of Enantioselective Proton Transfer to Carbon in Catalytic Antibody 14D9 分子名称: 1-(4-{[(2-HYDROXYETHYL)AMINO]CARBONYL}BENZYL)-1-METHYLPIPERIDINIUM, ANTIBODY 14D9, PHOSPHATE ION 著者 Baumann, U, Reymond, J.L. 登録日 2004-02-05 公開日 2004-02-27 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.79 Å) 主引用文献 Molecular Mechanism of Enantioselective Proton Transfer to Carbon in Catalytic Antibody 14D9 Proc.Natl.Acad.Sci.USA, 101, 2004
1WC7	FAB FRAGMENT OF PLP-DEPENDENT CATALYTIC ANTIBODY 15A9 IN COMPLEX WITH PHOSPHOPYRIDOXYL-L-ALANINE 分子名称: ALANYL-PYRIDOXAL-5'-PHOSPHATE, FAB FRAGMENT OF CATALYTIC ANTIBODY 15A9, HEAVY CHAIN, ... 著者 Golinelli-Pimpaneau, B, Christen, P. 登録日 2004-11-09 公開日 2005-11-30 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.33 Å) 主引用文献 Structure of a Pseudomerohedrally Twinned Monoclinic Crystal Form of a Pyridoxal Phosphate-Dependent Catalytic Antibody Acta Crystallogr.,Sect.D, 61, 2005
6APP	Anti-Marburgvirus Nucleoprotein Single Domain Antibody A Complexed with Nucleoprotein C-terminal domain 分子名称: Anti-Marburgvirus Nucleoprotein Single Domain Antibody A, Nucleoprotein 著者 Taylor, A.B, Garza, J.A. 登録日 2017-08-17 公開日 2017-10-11 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Unveiling a Drift Resistant Cryptotope withinMarburgvirusNucleoprotein Recognized by Llama Single-Domain Antibodies. Front Immunol, 8, 2017

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