3CFJ

Crystal structure of catalytic elimination antibody 34E4, orthorhombic crystal form

Summary for 3CFJ

• Entry DOI: 10.2210/pdb3cfj/pdb
• Related: 1Y0L 1Y18 3CFK
• Descriptor: CATALYTIC ANTIBODY FAB 34E4 LIGHT CHAIN fusion, CATALYTIC ANTIBODY FAB 34E4 HEAVY CHAIN fusion, GLYCEROL, ... (5 entities in total)
• Functional Keywords: immunoglobulin, catalytic antibody, chimeric fab, apo form, proton transfer, conformational change, immune system, immunoglobulin domain, immunoglobulin v region
• Biological source: Mus musculus (Mouse); More
• Total number of polymer chains: 8
• Total formula weight: 192407.03

Authors

Debler, E.W.,Wilson, I.A. (deposition date: 2008-03-04, release date: 2008-04-15, Last modification date: 2023-08-30)

• Primary citation: Debler, E.W.,Muller, R.,Hilvert, D.,Wilson, I.A.; Conformational isomerism can limit antibody catalysis.; J.Biol.Chem., 283:16554-16560, 2008; PubMed: 18417480; DOI: 10.1074/jbc.M710256200

Experimental method

X-RAY DIFFRACTION (2.6 Å)