3CFJ

Crystal structure of catalytic elimination antibody 34E4, orthorhombic crystal form

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E, G (L, A, C, E)	CATALYTIC ANTIBODY FAB 34E4 LIGHT CHAIN fusion	polymer	216	23258.8	4	UniProt (Q8TCD0) Pfam (PF07686) Pfam (PF07654)	Mus musculus (Mouse)
2	B, D, F, H (H, B, D, F)	CATALYTIC ANTIBODY FAB 34E4 HEAVY CHAIN fusion	polymer	227	24701.8	4	UniProt (A8K008) Pfam (PF07654) UniProt (by SIFTS) (P01857)	Mus musculus (Mouse)
3	I, K, L (L, A, C)	GLYCEROL	non-polymer		92.1	3	Chemie (GOL)
4	J, M, N (H, D)	SULFATE ION	non-polymer		96.1	3	Chemie (SO4)
5	O, P, Q, R, S... (L, H, A, B, C...)	water	water		18.0	518	Chemie (HOH)

Sequence modifications

L, A, C, E: 1 - 105 (PDB: 3CFJ)
L, A, C, E: 106 - 214 (UniProt: Q8TCD0)
H, B, D, F: 1 - 103 (PDB: 3CFJ)
H, B, D, F: 104 - 231 (UniProt: A8K008)

PDB	External Database	Details
Ser 108	Thr 137	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	191842.6
Non-Polymers*	Number of molecules	6
	Total formula weight	564.5
All*	Total formula weight	192407.0

*Water molecules are not included.