8C8P
Structure of the SARS-CoV-2 spike glycoprotein in complex with the 10D12 heavy-chain-only antibody (local refinement)
Summary for 8C8P
| Entry DOI | 10.2210/pdb8c8p/pdb |
| EMDB information | 16480 16481 16490 |
| Descriptor | Heavy-chain-only antibody 10D12, Spike glycoprotein,SARS-CoV-2 spike glycoprotein (2 entities in total) |
| Functional Keywords | complex, spike, glycoprotein, antibody, viral protein |
| Biological source | Mus musculus More |
| Total number of polymer chains | 2 |
| Total formula weight | 183746.30 |
| Authors | Serna Martin, I.,Hurdiss, D.L. (deposition date: 2023-01-20, release date: 2023-02-22, Last modification date: 2023-03-22) |
| Primary citation | Du, W.,Janssens, R.,Mykytyn, A.Z.,Li, W.,Drabek, D.,van Haperen, R.,Chatziandreou, M.,Rissmann, M.,van der Lee, J.,van Dortmondt, M.,Martin, I.S.,van Kuppeveld, F.J.M.,Hurdiss, D.L.,Haagmans, B.L.,Grosveld, F.,Bosch, B.J. Avidity engineering of human heavy-chain-only antibodies mitigates neutralization resistance of SARS-CoV-2 variants. Front Immunol, 14:1111385-1111385, 2023 Cited by PubMed: 36895554DOI: 10.3389/fimmu.2023.1111385 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (4.1 Å) |
Structure validation
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