PDB: 223166 件ウェブページステータス検索Chemie searchBIRD

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6RUQ	Structure of GluA2cryst in complex the antagonist ZK200775 and the negative allosteric modulator GYKI53655 at 4.65 A resolution 分子名称: (8R)-5-(4-aminophenyl)-N,8-dimethyl-8,9-dihydro-2H,7H-[1,3]dioxolo[4,5-h][2,3]benzodiazepine-7-carboxamide, Glutamate receptor 2, beta-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Krintel, C, Venskutonyte, R, Mirza, O.A, Gajhede, M, Kastrup, J.S. 登録日 2019-05-28 公開日 2020-06-24 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (4.65 Å) 主引用文献 Binding of a negative allosteric modulator and competitive antagonist can occur simultaneously at the ionotropic glutamate receptor GluA2. Febs J., 288, 2021
7RCO	Crystal structure of human TGF-beta-2 bound to 4A11.V2 Fab 分子名称: 4A11.V2 Fab Heavy Chain, 4A11.V2 Fab Light Chain, Transforming growth factor beta-2 著者 Yin, J, Lupardus, P.J, Sudhamsu, J. 登録日 2021-07-07 公開日 2021-09-29 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Dramatic activation of an antibody by a single amino acid change in framework. Sci Rep, 11, 2021
5KJR	Crystal structure of the ADCC-potent antibody N60-i3 Fab in complex with HIV-1 Clade A/E gp120 W69A/S115W mutant and M48U1. 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, M48U1 CD4 MIMETIC PEPTIDE, ... 著者 Tolbert, W.D, Pazgier, M. 登録日 2016-06-20 公開日 2016-07-20 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.98 Å) 主引用文献 A Highly Conserved gp120 Inner Domain Residue Modulates Env Conformation and Trimer Stability. J.Virol., 90, 2016
7ZKX	SRPK2 IN COMPLEX WITH INHIBITOR 分子名称: 1,2-ETHANEDIOL, ACETATE ION, N-[3-[[[2-(6-chloranyl-5-fluoranyl-1H-benzimidazol-2-yl)pyrimidin-4-yl]amino]methyl]pyridin-2-yl]-N-methyl-methanesulfonamide, ... 著者 Graedler, U. 登録日 2022-04-13 公開日 2023-02-22 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.06 Å) 主引用文献 MSC-1186, a Highly Selective Pan-SRPK Inhibitor Based on an Exceptionally Decorated Benzimidazole-Pyrimidine Core. J.Med.Chem., 66, 2023
5V0S	Crystal structure of the ACT domain of prephenate dehydrogenase tyrA from Bacillus anthracis 分子名称: CALCIUM ION, Prephenate dehydrogenase, SULFATE ION 著者 Shabalin, I.G, Hou, J, Cymborowski, M.T, Otwinowski, Z, Kwon, K, Christendat, D, Gritsunov, A, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2017-02-28 公開日 2017-03-08 最終更新日 2022-03-23 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Structural and biochemical analysis of Bacillus anthracis prephenate dehydrogenase reveals an unusual mode of inhibition by tyrosine via the ACT domain. Febs J., 287, 2020
5UYY	Crystal structure of prephenate dehydrogenase tyrA from Bacillus anthracis in complex with L-tyrosine 分子名称: Prephenate dehydrogenase, TYROSINE 著者 Shabalin, I.G, Hou, J, Cymborowski, M.T, Kwon, K, Christendat, D, Gritsunov, A.O, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2017-02-24 公開日 2017-03-08 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural and biochemical analysis of Bacillus anthracis prephenate dehydrogenase reveals an unusual mode of inhibition by tyrosine via the ACT domain. Febs J., 287, 2020
6VRS	Single particle reconstruction of glucose isomerase from Streptomyces rubiginosus based on data acquired in the presence of substantial aberrations 分子名称: MANGANESE (II) ION, xylose isomerase 著者 Bromberg, R, Guo, Y, Borek, D, Otwinowski, Z. 登録日 2020-02-09 公開日 2020-02-19 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 High-resolution cryo-EM reconstructions in the presence of substantial aberrations Iucrj, 7, 2020
6VSC	Single particle reconstruction of HemQ from Geobacillus based on data acquired in the presence of substantial aberrations 分子名称: HemQ 著者 Bromberg, R, Guo, Y, Borek, D, Otwinowski, Z. 登録日 2020-02-11 公開日 2020-02-19 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (2.6 Å) 主引用文献 High-resolution cryo-EM reconstructions in the presence of substantial aberrations Iucrj, 7, 2020
6VSA	Single particle reconstruction of HemQ from Geobacillus based on data acquired in the presence of substantial aberrations 分子名称: HemQ 著者 Bromberg, R, Guo, Y, Borek, D, Otwinowski, Z. 登録日 2020-02-10 公開日 2020-02-19 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (2.32 Å) 主引用文献 High-resolution cryo-EM reconstructions in the presence of substantial aberrations Iucrj, 7, 2020
4NM5	Crystal structure of GSK-3/Axin complex bound to phosphorylated Wnt receptor LRP6 c-motif 分子名称: ADENOSINE-5'-DIPHOSPHATE, Axin-1, CHLORIDE ION, ... 著者 Stamos, J.L, Chu, M.L.-H, Enos, M.D, Shah, N, Weis, W.I. 登録日 2013-11-14 公開日 2014-03-26 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural basis of GSK-3 inhibition by N-terminal phosphorylation and by the Wnt receptor LRP6. Elife, 3, 2014
7SAU	Structure of GldLM, the proton-powered motor that drives Type IX protein secretion and gliding motility in Schleiferia thermophila 分子名称: GldM, Gliding motility protein GldL 著者 Hennell James, R, Deme, J.C, Lea, S.M. 登録日 2021-09-23 公開日 2022-03-23 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structures of the Type IX Secretion/Gliding Motility Motor from across the Phylum Bacteroidetes. Mbio, 13, 2022
4UON	Crystal structure of C-terminal truncated (110-265) Aura virus capsid protease. 分子名称: CAPSID PROTEASE, GLYCEROL 著者 Aggarwal, M, Kumar, P, Tomar, S. 登録日 2014-06-05 公開日 2014-06-18 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 Trans-Protease Activity and Structural Insights Into the Active Form of the Alphavirus Capsid Protease. J.Virol., 88, 2014
4WA2	The crystal structure of hemagglutinin from a H3N8 influenza virus isolated from New England harbor seals in complex with 3'SLN 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... 著者 Yang, H, Villanueva, J.M, Gubareva, L.V, Stevens, J. 登録日 2014-08-28 公開日 2015-01-14 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural and Functional Analysis of Surface Proteins from an A(H3N8) Influenza Virus Isolated from New England Harbor Seals. J.Virol., 89, 2015
4NU1	Crystal structure of a transition state mimic of the GSK-3/Axin complex bound to phosphorylated N-terminal auto-inhibitory pS9 peptide 分子名称: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Axin-1, ... 著者 Chu, M.L.-H, Stamos, J.L, Enos, M.D, Shah, N, Weis, W.I. 登録日 2013-12-03 公開日 2014-03-26 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural basis of GSK-3 inhibition by N-terminal phosphorylation and by the Wnt receptor LRP6. Elife, 3, 2014
4JTA	Crystal structure of Kv1.2-2.1 paddle chimera channel in complex with Charybdotoxin 分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, POTASSIUM ION, ... 著者 MacKinnon, R, Banerjee, A, Lee, A, Campbell, E. 登録日 2013-03-23 公開日 2013-06-12 最終更新日 2019-12-25 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure of a pore-blocking toxin in complex with a eukaryotic voltage-dependent K(+) channel. Elife, 2, 2013
6S8M	S. pombe microtubule decorated with Cut7 motor domain in the AMPPNP state 分子名称: 7,11-DIHYDROXY-8,8,10,12,16-PENTAMETHYL-3-[1-METHYL-2-(2-METHYL-THIAZOL-4-YL)VINYL]-4,17-DIOXABICYCLO[14.1.0]HEPTADECANE-5,9-DIONE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Moores, C.A, von Loeffelholz, O. 登録日 2019-07-10 公開日 2019-08-21 最終更新日 2023-09-20 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 Cryo-EM Structure (4.5- angstrom ) of Yeast Kinesin-5-Microtubule Complex Reveals a Distinct Binding Footprint and Mechanism of Drug Resistance. J.Mol.Biol., 431, 2019
4LV0	AmpC beta-lactamase in complex with m-aminophenyl boronic acid 分子名称: Beta-lactamase, M-AMINOPHENYLBORONIC ACID, PHOSPHATE ION 著者 London, N, Eidam, O, Shoichet, B.K. 登録日 2013-07-25 公開日 2014-07-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.652 Å) 主引用文献 Covalent docking of large libraries for the discovery of chemical probes. Nat.Chem.Biol., 10, 2014
4LV2	AmpC beta-lactamase in complex with [1-(6-chloropyrimidin-4-yl)-1H-pyrazol-4-yl] boronic acid 分子名称: Beta-lactamase, PHOSPHATE ION, [1-(6-chloropyrimidin-4-yl)-1H-pyrazol-4-yl]boronic acid 著者 London, N, Eidam, O, Shoichet, B.K. 登録日 2013-07-25 公開日 2014-07-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Covalent docking of large libraries for the discovery of chemical probes. Nat.Chem.Biol., 10, 2014
4LV3	AmpC beta-lactamase in complex with (3,5-di-tert-butylphenyl) boronic acid 分子名称: (3,5-di-tert-butylphenyl)boronic acid, Beta-lactamase, PHOSPHATE ION 著者 London, N, Eidam, O, Shoichet, B.K. 登録日 2013-07-25 公開日 2014-07-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 Covalent docking of large libraries for the discovery of chemical probes. Nat.Chem.Biol., 10, 2014
4LV1	AmpC beta-lactamase in complex with [1-(3-chlorophenyl)-1H-pyrazol-4-yl] boronic acid 分子名称: Beta-lactamase, PHOSPHATE ION, [1-(3-chlorophenyl)-1H-pyrazol-4-yl]boronic acid 著者 London, N, Eidam, O, Shoichet, B.K. 登録日 2013-07-25 公開日 2014-07-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 Covalent docking of large libraries for the discovery of chemical probes. Nat.Chem.Biol., 10, 2014
4OGR	crystal structure of P-TEFb complex with AFF4 and Tat 分子名称: ADENOSINE, AF4/FMR2 family member 4, Cyclin-T1, ... 著者 Schulze-Gahmen, U, Alber, T. 登録日 2014-01-16 公開日 2014-05-07 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 AFF4 binding to Tat-P-TEFb indirectly stimulates TAR recognition of super elongation complexes at the HIV promoter. Elife, 3, 2014
4JTD	Crystal structure of Kv1.2-2.1 paddle chimera channel in complex with Lys27Met mutant of Charybdotoxin 分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, POTASSIUM ION, ... 著者 Banerjee, A, Lee, A, Campbell, E, MacKinnon, R. 登録日 2013-03-23 公開日 2013-06-12 最終更新日 2019-12-25 実験手法 X-RAY DIFFRACTION (2.54 Å) 主引用文献 Structure of a pore-blocking toxin in complex with a eukaryotic voltage-dependent K(+) channel. Elife, 2, 2013
4JTC	Crystal structure of Kv1.2-2.1 paddle chimera channel in complex with Charybdotoxin in Cs+ 分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, CESIUM ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... 著者 Banerjee, A, Lee, A, Campbell, E, MacKinnon, R. 登録日 2013-03-23 公開日 2013-06-12 最終更新日 2019-12-25 実験手法 X-RAY DIFFRACTION (2.56 Å) 主引用文献 Structure of a pore-blocking toxin in complex with a eukaryotic voltage-dependent K(+) channel. Elife, 2, 2013
4NBI	D-aminoacyl-tRNA deacylase (DTD) from Plasmodium falciparum in complex with D-tyrosyl-3'-aminoadenosine at 1.86 Angstrom resolution 分子名称: 3'-deoxy-3'-(D-tyrosylamino)adenosine, D-tyrosyl-tRNA(Tyr) deacylase, TRIETHYLENE GLYCOL 著者 Ahmad, S, Routh, S.B, Kamarthapu, V, Sankaranarayanan, R. 登録日 2013-10-23 公開日 2013-12-18 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Mechanism of chiral proofreading during translation of the genetic code. Elife, 2, 2013
8GH8	RuvA Holliday junction DNA complex 分子名称: DNA (34-MER), Holliday junction branch migration complex subunit RuvA 著者 Rish, A.D, Fu, T. 登録日 2023-03-09 公開日 2023-05-10 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 RuvA Holliday junction DNA complex To Be Published

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