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2L5Y
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NMR structure of calcium-loaded STIM2 EF-SAM.
分子名称: CALCIUM ION, Stromal interaction molecule 2
著者Zheng, L, Stathopulos, P.B, Ikura, M.
登録日2010-11-09
公開日2011-01-19
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Auto-inhibitory role of the EF-SAM domain of STIM proteins in store-operated calcium entry.
Proc.Natl.Acad.Sci.USA, 108, 2011
2JW2
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Validation of inter-helical orientation of the steril-alpha-motif of human deleted in liver cancer 2 by residual dipolar couplings
分子名称: StAR-related lipid transfer protein 13
著者Li, H, Sze, K, Fung, K.
登録日2007-10-03
公開日2008-10-21
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Validation of inter-helical orientation of the steril-alpha-motif of human deleted in liver cancer 2 by residual dipolar couplings
To be Published
2KG5
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NMR Solution structure of ARAP3-SAM
分子名称: Arf-GAP, Rho-GAP domain, ANK repeat and PH domain-containing protein 3
著者Leone, M, Pellecchia, M.
登録日2009-03-05
公開日2009-11-17
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The Sam domain of the lipid phosphatase Ship2 adopts a common model to interact with Arap3-Sam and EphA2-Sam.
Bmc Struct.Biol., 9, 2009
2H80
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NMR structures of SAM domain of Deleted in Liver Cancer 2 (DLC2)
分子名称: StAR-related lipid transfer protein 13
著者Li, H.Y, Fung, K.L, Jin, D.Y, Chung, S.S, Ko, B.C, Sun, H.Z.
登録日2006-06-06
公開日2007-05-15
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structures, dynamics, and lipid-binding of the sterile alpha-motif domain of the deleted in liver cancer 2
Proteins, 67, 2007
2KAP
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BU of 2kap by Molmil
Solution structure of DLC1-SAM
分子名称: Rho GTPase-activating protein 7
著者Yang, S, Yang, D.
登録日2008-11-12
公開日2009-10-20
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Characterization of DLC1-SAM equilibrium unfolding at the amino acid residue level
Biochemistry, 48, 2009
2GLE
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Solution structure of neurabin SAM domain
分子名称: Neurabin-1
著者Ju, T, Hudak, J, Peti, W.
登録日2006-04-04
公開日2007-03-13
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structural characterization of the neurabin SAM domain
TO BE PUBLISHED
2K60
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NMR structure of calcium-loaded STIM1 EF-SAM
分子名称: CALCIUM ION, PROTEIN (Stromal interaction molecule 1)
著者Stathopulos, P.B, Ikura, M.
登録日2008-07-02
公開日2008-10-07
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structural and mechanistic insights into STIM1-mediated initiation of store-operated calcium entry.
Cell(Cambridge,Mass.), 135, 2008
2GYT
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BU of 2gyt by Molmil
Solution structure of the SAM (sterile alpha motif) domain of DLC1 (deleted in liver cancer 1)
分子名称: Deleted in liver cancer 1 protein, isoform 2
著者Yang, S.
登録日2006-05-10
公開日2007-04-24
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献The SAM domain of the RhoGAP DLC1 binds EF1A1 to regulate cell migration
J.Cell.Sci., 122, 2009
2DKY
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BU of 2dky by Molmil
Solution structure of the SAM-domain of Rho-GTPase-activating protein 7
分子名称: Rho-GTPase-activating protein 7
著者Goroncy, A.K, Sato, M, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2006-04-14
公開日2007-04-24
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the SAM-domain of Rho-GTPase-activating protein 7
To be Published
2E8O
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Solution structure of the N-terminal SAM-domain of the SAM domain and HD domain containing protein 1 (Dendritic cell-derived IFNG-induced protein) (DCIP) (Monocyte protein 5) (MOP-5)
分子名称: SAM domain and HD domain-containing protein 1
著者Goroncy, A.K, Tochio, N, Koshiba, S, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-01-22
公開日2007-07-24
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the N-terminal SAM-domain of the SAM domain and HD domain containing protein 1 (Dendritic cell-derived IFNG-induced protein) (DCIP) (Monocyte protein 5) (MOP-5)
To be Published
2EAP
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Solution structure of the N-terminal SAM-domain of human lymphocyte cytosolic protein 2
分子名称: Lymphocyte cytosolic protein 2
著者Goroncy, A.K, Sato, M, Tochio, N, Koshiba, S, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-01-31
公開日2008-02-05
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the N-terminal SAM-domain of human lymphocyte cytosolic protein 2
To be Published
2B6G
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RNA recognition by the Vts1 SAM domain
分子名称: 5'-R(*GP*GP*AP*GP*GP*CP*UP*CP*UP*GP*GP*CP*AP*GP*CP*UP*UP*UP*C)-3', Vts1p
著者Donaldson, L.W, Johnson, P.E.
登録日2005-10-01
公開日2006-01-24
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献RNA recognition by the Vts1p SAM domain
Nat.Struct.Mol.Biol., 13, 2006
2ESE
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Structure of the SAM domain of Vts1p in complex with RNA
分子名称: 5'-R(*GP*GP*AP*GP*AP*GP*GP*CP*UP*CP*UP*GP*GP*CP*AP*GP*CP*UP*UP*UP*UP*CP*C)-3', Vts1p
著者Allain, F.H.T.
登録日2005-10-26
公開日2006-01-24
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Shape-specific recognition in the structure of the Vts1p SAM domain with RNA.
Nat.Struct.Mol.Biol., 13, 2006
2D3D
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BU of 2d3d by Molmil
crystal structure of the RNA binding SAM domain of saccharomyces cerevisiae Vts1
分子名称: CALCIUM ION, Vts1 protein
著者Aviv, T, Amborski, A.N, Zhao, X.S, Kwan, J.J, Johnson, P.E, Sicheri, F, Donaldson, L.W.
登録日2005-09-27
公開日2006-02-14
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The NMR and X-ray Structures of the Saccharomyces cerevisiae Vts1 SAM Domain Define a Surface for the Recognition of RNA Hairpins
J.Mol.Biol., 356, 2006
2DL0
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BU of 2dl0 by Molmil
Solution structure of the SAM-domain of the SAM and SH3 domain containing protein 1
分子名称: SAM and SH3 domain-containing protein 1
著者Goroncy, A.K, Sato, M, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2006-04-14
公開日2006-10-14
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the SAM-domain of the SAM and SH3 domain containing protein 1
To be Published
2ES6
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BU of 2es6 by Molmil
Structure of the SAM domain of Vts1p
分子名称: Vts1p
著者Allain, F.H.T.
登録日2005-10-25
公開日2006-01-24
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Shape-specific recognition in the structure of the Vts1p SAM domain with RNA.
Nat.Struct.Mol.Biol., 13, 2006
2F8K
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Sequence specific recognition of RNA hairpins by the SAM domain of Vts1
分子名称: 5'-R(*UP*AP*AP*UP*CP*UP*UP*UP*GP*AP*CP*AP*GP*AP*UP*U)-3', Protein VTS1
著者Aviv, T, Lin, Z, Ben-Ari, G, Smibert, C.A, Sicheri, F.
登録日2005-12-02
公開日2006-01-24
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Sequence-specific recognition of RNA hairpins by the SAM domain of Vts1p.
Nat.Struct.Mol.Biol., 13, 2006
7QG0
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BU of 7qg0 by Molmil
Inhibitor-induced hSARM1 duplex
分子名称: NAD(+) hydrolase SARM1
著者Zalk, R, Kahzma, T, Guez-Haddad, J.
登録日2021-12-07
公開日2022-12-21
最終更新日2023-01-11
実験手法ELECTRON MICROSCOPY (4.02 Å)
主引用文献A duplex structure of SARM1 octamers stabilized by a new inhibitor.
Cell.Mol.Life Sci., 80, 2022
7ANW
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hSARM1 NAD+ complex
分子名称: NAD(+) hydrolase SARM1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Sporny, M, Guez-Haddad, J, Khazma, T, Yaron, A, Mim, C, Isupov, M.N, Zalk, R, Dessau, M, Hons, M, Opatowsky, Y.
登録日2020-10-13
公開日2020-11-11
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (2.68 Å)
主引用文献Structural basis for SARM1 inhibition and activation under energetic stress.
Elife, 9, 2020
6WPK
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BU of 6wpk by Molmil
SARM1 Autoinhibited Conformation
分子名称: NAD(+) hydrolase SARM1
著者Xie, T, Bratkowski, M, Bai, X, Sambashivan, S.
登録日2020-04-27
公開日2020-08-12
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural and Mechanistic Regulation of the Prodegenerative NAD Hydrolase SARM1
Cell Rep, 32, 2020
7KNQ
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SARM1 Octamer
分子名称: NAD(+) hydrolase SARM1
著者Shen, C, Wu, H.
登録日2020-11-05
公開日2021-11-17
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Multiple domain interfaces mediate SARM1 autoinhibition.
Proc.Natl.Acad.Sci.USA, 118, 2021
4TWO
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BU of 4two by Molmil
Human EphA3 Kinase domain in complex with compound 164
分子名称: 5-{[3-carbamoyl-4-(3,4-dimethylphenyl)-5-methylthiophen-2-yl]amino}-5-oxopentanoic acid, Ephrin type-A receptor 3
著者Dong, J, Caflisch, A.
登録日2014-07-01
公開日2015-05-13
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.047 Å)
主引用文献Structural Analysis of the Binding of Type I, I1/2, and II Inhibitors to Eph Tyrosine Kinases.
Acs Med.Chem.Lett., 6, 2015
4TWN
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Human EphA3 Kinase domain in complex with Birb796
分子名称: 1-(5-TERT-BUTYL-2-P-TOLYL-2H-PYRAZOL-3-YL)-3-[4-(2-MORPHOLIN-4-YL-ETHOXY)-NAPHTHALEN-1-YL]-UREA, Ephrin type-A receptor 3
著者Dong, J, Caflisch, A.
登録日2014-07-01
公開日2015-05-13
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.706 Å)
主引用文献Structural Analysis of the Binding of Type I, I1/2, and II Inhibitors to Eph Tyrosine Kinases.
Acs Med.Chem.Lett., 6, 2015
8P2L
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A CHIMERA construct containing human SARM1 ARM and SAM domains and C. elegans TIR domain.
分子名称: NAD(+) hydrolase SARM1,NAD(+) hydrolase tir-1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Isupov, M.N, Opatowsky, Y.
登録日2023-05-16
公開日2023-09-06
実験手法ELECTRON MICROSCOPY (2.68 Å)
主引用文献Structure-function analysis of ceTIR-1/hSARM1 explains the lack of Wallerian axonal degeneration in C. elegans.
Cell Rep, 42, 2023
7LD0
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Cryo-EM structure of ligand-free Human SARM1
分子名称: NAD(+) hydrolase SARM1
著者Nanson, J.D, Gu, W, Luo, Z, Jia, X, Landsberg, M.J, Kobe, B, Ve, T.
登録日2021-01-12
公開日2021-03-10
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献SARM1 is a metabolic sensor activated by an increased NMN/NAD + ratio to trigger axon degeneration.
Neuron, 109, 2021

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