NMR structure of calcium-loaded STIM2 EF-SAM.

Summary for 2L5Y

DescriptorStromal interaction molecule 2, CALCIUM ION (2 entities in total)
Functional Keywordsstromal interaction molecule, ef-hand, sam domain, store operated calcium entry, signaling protein
Biological sourceHomo sapiens (human)
Cellular locationEndoplasmic reticulum membrane; Single-pass type I membrane protein Q9P246
Total number of polymer chains1
Total molecular weight17871.05
Zheng, L.,Stathopulos, P.B.,Ikura, M. (deposition date: 2010-11-09, release date: 2011-01-19, Last modification date: 2011-07-13)
Primary citation
Zheng, L.,Stathopulos, P.B.,Schindl, R.,Li, G.Y.,Romanin, C.,Ikura, M.
Auto-inhibitory role of the EF-SAM domain of STIM proteins in store-operated calcium entry.
Proc.Natl.Acad.Sci.USA, 108:1337-1342, 2011
PubMed: 21217057 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.1015125108
MImport into Mendeley
Experimental method
NMR Information

Structure validation

ClashscoreRamachandran outliersSidechain outliers111.3%7.6%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures

More Asymmetric unit images

Molmil generated image of 2l5y
no rotation
Molmil generated image of 2l5y
rotated about x axis by 90°
Molmil generated image of 2l5y
rotated about y axis by 90°
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