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6NK2
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EphA2 LBD in complex with bA-WLA-YRPK bio peptide
分子名称: DI(HYDROXYETHYL)ETHER, Ephrin type-A receptor 2, bA-WLA-YPRKbio peptide
著者Lechtenberg, B.C, Pasquale, E.B.
登録日2019-01-04
公開日2019-05-01
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Engineering nanomolar peptide ligands that differentially modulate EphA2 receptor signaling.
J.Biol.Chem., 294, 2019
2WO1
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Crystal Structure of the EphA4 Ligand Binding Domain
分子名称: EPHRIN TYPE-A RECEPTOR, N-PROPANOL
著者Bowden, T.A, Aricescu, A.R, Nettleship, J.E, Siebold, C, Rahman-Huq, N, Owens, R.J, Stuart, D.I, Jones, E.Y.
登録日2009-07-21
公開日2009-10-27
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural Plasticity of Eph-Receptor A4 Facilitates Cross-Class Ephrin Signalling
Structure, 17, 2009
6NK0
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EphA2 LBD in complex with bA-WLA-Yam peptide
分子名称: 1,2-ETHANEDIOL, 6-AMINOHEXANOIC ACID, DI(HYDROXYETHYL)ETHER, ...
著者Lechtenberg, B.C, Pasquale, E.B.
登録日2019-01-04
公開日2019-05-01
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献Engineering nanomolar peptide ligands that differentially modulate EphA2 receptor signaling.
J.Biol.Chem., 294, 2019
7B7N
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Human herpesvirus-8 gH/gL in complex with EphA2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
著者Pederzoli, R, Guardado-Calvo, P, Rey, F.A, Backovic, M.
登録日2020-12-11
公開日2020-12-30
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献Human herpesvirus 8 molecular mimicry of ephrin ligands facilitates cell entry and triggers EphA2 signaling.
Plos Biol., 19, 2021
7CZF
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Crystal structure of Kaposi Sarcoma associated herpesvirus (KSHV ) gHgL in complex with the ligand binding domian (LBD) of EphA2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Su, C, Wu, L.L, Song, H, Chai, Y, Qi, J.X, Yan, J.H, Gao, G.F.
登録日2020-09-08
公開日2020-10-21
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Molecular basis of EphA2 recognition by gHgL from gammaherpesviruses.
Nat Commun, 11, 2020
7CZE
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Crystal structure of Epstein-Barr virus (EBV) gHgL and in complex with the ligand binding domian (LBD) of EphA2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein H, Envelope glycoprotein L, ...
著者Su, C, Wu, L.L, Song, H, Chai, Y, Qi, J.X, Yan, J.H, Gao, G.F.
登録日2020-09-08
公開日2020-10-21
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Molecular basis of EphA2 recognition by gHgL from gammaherpesviruses.
Nat Commun, 11, 2020
7S7K
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Crystal structure of the EphB2 extracellular domain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ephrin type-B receptor 2, ...
著者Xu, Y, Xu, K, Nikolov, D.B.
登録日2021-09-16
公開日2021-10-27
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献The Ephb2 Receptor Uses Homotypic, Head-to-Tail Interactions within Its Ectodomain as an Autoinhibitory Control Mechanism.
Int J Mol Sci, 22, 2021
7K7J
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EphB6 receptor ectodomain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ephrin type-B receptor 6
著者Goldgur, Y, Himanen, J.
登録日2020-09-22
公開日2021-04-07
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3.004 Å)
主引用文献Structure of the EphB6 receptor ectodomain.
Plos One, 16, 2021
1KGY
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Crystal Structure of the EphB2-ephrinB2 complex
分子名称: EPHRIN TYPE-B RECEPTOR 2, EPHRIN-B2
著者Himanen, J.P, Rajashankar, K.R, Lackmann, M, Cowan, C.A, Henkemeyer, M, Nikolov, D.B.
登録日2001-11-28
公開日2002-05-28
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of an Eph receptor-ephrin complex.
Nature, 414, 2001
1SHW
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EphB2 / EphrinA5 Complex Structure
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ephrin type-B receptor 2, Ephrin-A5, ...
著者Himanen, J.P, Chumley, M.J, Lackmann, M, Li, C, Barton, W.A, Jeffrey, P.D, Vearing, C, Geleick, D, Feldheim, D.A, Boyd, A.W.
登録日2004-02-26
公開日2004-05-18
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Repelling class discrimination: ephrin-A5 binds to and activates EphB2 receptor signaling
Nat.Neurosci., 7, 2004
4L0P
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Structure of the human EphA3 receptor ligand binding domain complexed with ephrin-A5
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Ephrin type-A receptor 3, ...
著者Forse, G.J, Kolatkar, A.R, Kuhn, P.
登録日2013-05-31
公開日2014-06-11
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Distinctive Structure of the EphA3/Ephrin-A5 Complex Reveals a Dual Mode of Eph Receptor Interaction for Ephrin-A5.
Plos One, 10, 2015
2HLE
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Structural and biophysical characterization of the EPHB4-EPHRINB2 protein protein interaction and receptor specificity.
分子名称: Ephrin type-B receptor 4, Ephrin-B2
著者Chrencik, J.E, Brooun, A, Kuhn, P, Accelerated Technologies Center for Gene to 3D Structure (ATCG3D)
登録日2006-07-06
公開日2006-08-22
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structural and Biophysical Characterization of the EphB4-EphrinB2 Protein-Protein Interaction and Receptor Specificity.
J.Biol.Chem., 281, 2006
4M4R
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Epha4 ectodomain complex with ephrin a5
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ephrin type-A receptor 4, ...
著者Xu, K, Tsvetkova-Robev, D, Xu, Y, Goldgur, Y, Chan, Y.-P, Himanen, J.P, Nikolov, D.B.
登録日2013-08-07
公開日2013-10-30
最終更新日2024-11-27
実験手法X-RAY DIFFRACTION (3.13 Å)
主引用文献Insights into Eph receptor tyrosine kinase activation from crystal structures of the EphA4 ectodomain and its complex with ephrin-A5.
Proc.Natl.Acad.Sci.USA, 110, 2013
3MBW
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BU of 3mbw by Molmil
Crystal structure of the human ephrin A2 LBD and CRD domains in complex with ephrin A1
分子名称: Ephrin type-A receptor 2, Ephrin-A1, UNKNOWN ATOM OR ION, ...
著者Walker, J.R, Yermekbayeva, L, Seitova, A, Butler-Cole, C, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2010-03-26
公開日2010-06-09
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Architecture of Eph receptor clusters.
Proc.Natl.Acad.Sci.USA, 107, 2010
4M4P
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Crystal structure of EPHA4 ectodomain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ephrin type-A receptor 4
著者Xu, K, Tsvetkova-Robev, D, Xu, Y, Goldgur, Y, Chan, Y.-P, Himanen, J.P, Nikolov, D.B.
登録日2013-08-07
公開日2013-10-30
最終更新日2024-11-27
実験手法X-RAY DIFFRACTION (2.081 Å)
主引用文献Insights into Eph receptor tyrosine kinase activation from crystal structures of the EphA4 ectodomain and its complex with ephrin-A5.
Proc.Natl.Acad.Sci.USA, 110, 2013
3FL7
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BU of 3fl7 by Molmil
Crystal structure of the human ephrin A2 ectodomain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Ephrin receptor, ...
著者Walker, J.R, Yermekbayeva, L, Seitova, A, Butler-Cole, C, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2008-12-18
公開日2009-01-27
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Architecture of Eph receptor clusters.
Proc.Natl.Acad.Sci.USA, 107, 2010
3MX0
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Crystal Structure of EphA2 ectodomain in complex with ephrin-A5
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ephrin type-A receptor 2, ...
著者Himanen, J.P, Yermekbayeva, L, Janes, P.W, Walker, J.R, Xu, K, Atapattu, L, Rajashankar, K.R, Mensinga, A, Lackmann, M, Nikolov, D.B, Dhe-Paganon, S.
登録日2010-05-06
公開日2010-06-30
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (3.506 Å)
主引用文献Architecture of Eph receptor clusters.
Proc.Natl.Acad.Sci.USA, 107, 2010
3HEI
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Ligand Recognition by A-Class Eph Receptors: Crystal Structures of the EphA2 Ligand-Binding Domain and the EphA2/ephrin-A1 Complex
分子名称: Ephrin type-A receptor 2, Ephrin-A1
著者Himanen, J.P, Goldgur, Y, Miao, H, Myshkin, E, Guo, H, Buck, M, Nguyen, M, Rajashankar, K.R, Wang, B, Nikolov, D.B.
登録日2009-05-08
公開日2009-06-30
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Ligand recognition by A-class Eph receptors: crystal structures of the EphA2 ligand-binding domain and the EphA2/ephrin-A1 complex.
Embo Rep., 10, 2009
3GXU
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BU of 3gxu by Molmil
Crystal structure of Eph receptor and ephrin complex
分子名称: Ephrin type-A receptor 4, Ephrin-B2
著者Qin, H.N, Song, J.X.
登録日2009-04-03
公開日2009-10-27
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural characterization of the EphA4-ephrin-B2 complex reveals new features enabling Eph-ephrin binding promiscuity
J.Biol.Chem., 2009
3CZU
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BU of 3czu by Molmil
Crystal structure of the human ephrin A2- ephrin A1 complex
分子名称: Ephrin type-A receptor 2, Ephrin-A1, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Walker, J.R, Yermekbayeva, L, Seitova, A, Butler-Cole, C, Bountra, C, Wikstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2008-04-30
公開日2008-08-12
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Architecture of Eph receptor clusters.
Proc.Natl.Acad.Sci.USA, 107, 2010
4BKA
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crystal structure of the human EphA4 ectodomain in complex with human ephrin A5
分子名称: EPHRIN TYPE-A RECEPTOR 4, EPHRIN-A5
著者Seiradake, E, Schaupp, A, del Toro Ruiz, D, Kaufmann, R, Mitakidis, N, Harlos, K, Aricescu, A.R, Klein, R, Jones, E.Y.
登録日2013-04-23
公開日2013-07-03
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (5.3 Å)
主引用文献Structurally Encoded Intraclass Differences in Epha Clusters Drive Distinct Cell Responses
Nat.Struct.Mol.Biol., 20, 2013
4BK4
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crystal structure of the human EphA4 ectodomain
分子名称: EPHRIN TYPE-A RECEPTOR 4
著者Seiradake, E, Schaupp, A, del Toro Ruiz, D, Kaufmann, R, Mitakidis, N, Harlos, K, Aricescu, A.R, Klein, R, Jones, E.Y.
登録日2013-04-22
公開日2013-07-03
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (3.65 Å)
主引用文献Structurally Encoded Intraclass Differences in Epha Clusters Drive Distinct Cell Responses
Nat.Struct.Mol.Biol., 20, 2013
4BK5
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crystal structure of the human EphA4 ectodomain in complex with human ephrin A5 (amine-methylated sample)
分子名称: EPHRIN TYPE-A RECEPTOR 4, EPHRIN-A5
著者Seiradake, E, Schaupp, A, del Toro Ruiz, D, Kaufmann, R, Mitakidis, N, Harlos, K, Aricescu, A.R, Klein, R, Jones, E.Y.
登録日2013-04-22
公開日2013-07-03
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Structurally Encoded Intraclass Differences in Epha Clusters Drive Distinct Cell Responses
Nat.Struct.Mol.Biol., 20, 2013
4BKF
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crystal structure of the human EphA4 ectodomain in complex with human ephrinB3
分子名称: EPHRIN TYPE-A RECEPTOR 4, EPHRIN-B3
著者Seiradake, E, Schaupp, A, del Toro Ruiz, D, Kaufmann, R, Mitakidis, N, Harlos, K, Aricescu, A.R, Klein, R, Jones, E.Y.
登録日2013-04-24
公開日2013-07-03
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (4.65 Å)
主引用文献Structurally Encoded Intraclass Differences in Epha Clusters Drive Distinct Cell Responses
Nat.Struct.Mol.Biol., 20, 2013
2X10
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Crystal structure of the complete EphA2 ectodomain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, EPHRIN TYPE-A RECEPTOR 2
著者Seiradake, E, Harlos, K, Sutton, G, Aricescu, A.R, Jones, E.Y.
登録日2009-12-21
公開日2010-03-16
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献An Extracellular Steric Seeding Mechanism for Eph-Ephrin Signalling Platform Assembly
Nat.Struct.Mol.Biol., 17, 2010

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