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3CZU

Crystal structure of the human ephrin A2- ephrin A1 complex

Summary for 3CZU
Entry DOI10.2210/pdb3czu/pdb
Related1MQB 3C8X
DescriptorEphrin type-A receptor 2, Ephrin-A1, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
Functional Keywordsatp-binding, kinase, nucleotide-binding, receptor, transferase, phosphorylation, transmembrane, tyrosine-protein kinase, glycoprotein, structural genomics consortium, sgc, phosphoprotein, gpi-anchor, lipoprotein, transferase-signaling protein complex, transferase/signaling protein
Biological sourceHomo sapiens
More
Cellular locationCell membrane; Single-pass type I membrane protein: P29317
Cell membrane; Lipid-anchor, GPI-anchor. Ephrin-A1, secreted form: Secreted: P20827
Total number of polymer chains2
Total formula weight45695.90
Authors
Primary citationHimanen, J.P.,Yermekbayeva, L.,Janes, P.W.,Walker, J.R.,Xu, K.,Atapattu, L.,Rajashankar, K.R.,Mensinga, A.,Lackmann, M.,Nikolov, D.B.,Dhe-Paganon, S.
Architecture of Eph receptor clusters.
Proc.Natl.Acad.Sci.USA, 107:10860-10865, 2010
Cited by
PubMed: 20505120
DOI: 10.1073/pnas.1004148107
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.65 Å)
Structure validation

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