6NK2

EphA2 LBD in complex with bA-WLA-YRPK bio peptide

Summary for 6NK2

Entry DOI	10.2210/pdb6nk2/pdb
Descriptor	Ephrin type-A receptor 2, bA-WLA-YPRKbio peptide, DI(HYDROXYETHYL)ETHER, ... (4 entities in total)
Functional Keywords	protein-peptide interaction, kinase, ephrin, eph receptor, drug development, signaling protein, transferase
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	46114.15
Authors	Lechtenberg, B.C.,Pasquale, E.B. (deposition date: 2019-01-04, release date: 2019-05-01, Last modification date: 2023-10-11)
Primary citation	Gomez-Soler, M.,Petersen Gehring, M.,Lechtenberg, B.C.,Zapata-Mercado, E.,Hristova, K.,Pasquale, E.B. Engineering nanomolar peptide ligands that differentially modulate EphA2 receptor signaling. J.Biol.Chem., 294:8791-8805, 2019 Cited by PubMed: 31015204 DOI: 10.1074/jbc.RA119.008213 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation