1SHW

EphB2 / EphrinA5 Complex Structure

Summary for 1SHW
Related1NUK 1SHX
Related PRD IDPRD_900017
DescriptorEphrin-A5, Ephrin type-B receptor 2, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
Functional Keywordsreceptor tyrosine kinase, ephrin signaling, hormone-growth factor-receptor complex, hormone/growth factor/receptor
Biological sourceMus musculus (house mouse)
More
Total number of polymer chains2
Total formula weight37897.90
Authors
Himanen, J.P.,Chumley, M.J.,Lackmann, M.,Li, C.,Barton, W.A.,Jeffrey, P.D.,Vearing, C.,Geleick, D.,Feldheim, D.A.,Boyd, A.W. (deposition date: 2004-02-26, release date: 2004-05-18, Last modification date: 2020-07-29)
Primary citationBarton, W.A.,Boyd, A.W.,Chumley, M.J.,Feldheim, D.A.,Geleick, D.,Henkemeyer, M.,Himanen, J.P.,Jeffrey, P.D.,Lackmann, M.,Li, C.,Nikolov, D.B.,Vearing, C.
Repelling class discrimination: ephrin-A5 binds to and activates EphB2 receptor signaling
Nat.Neurosci., 7:501-509, 2004
PubMed: 15107857
DOI: 110.1038/nn1237
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.2 Å)
Structure validation
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PDB entries from 2021-06-16