PDB: 109 件ウェブページステータス検索Chemie searchBIRD

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2NVH	Determination of Solvent Content in Cavities in Interleukin-1 Using Experimentally-Phased Electron Density 分子名称: Interleukin-1 beta, SULFATE ION 著者 Quillin, M.L, Matthews, B.W. 登録日 2006-11-12 公開日 2006-12-12 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 Determination of solvent content in cavities in IL-1beta using experimentally phased electron density Proc.Natl.Acad.Sci.Usa, 103, 2006
2VXT	Crystal structure of human IL-18 complexed to murine reference antibody 125-2H Fab 分子名称: CHLORIDE ION, INTERLEUKIN-18, MAGNESIUM ION, ... 著者 Argiriadi, M.A, Xiang, T, Wu, C, Ghayur, T, Borhani, D.W. 登録日 2008-07-10 公開日 2009-06-23 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.49 Å) 主引用文献 Unusual Water-Mediated Antigenic Recognition of the Proinflammatory Cytokine Interleukin-18. J.Biol.Chem., 284, 2009
2WRY	Crystal structure of chicken cytokine interleukin 1 beta 分子名称: INTERLEUKIN-1BETA 著者 Lu, W.S, Cheng, C.S, Lyu, P.C, Lee, L.H, Wang, W.C, Yin, H.S. 登録日 2009-09-03 公開日 2010-09-29 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.58 Å) 主引用文献 Structural and Functional Comparison of Cytokine Interleukin-1 Beta from Chicken and Human. Mol.Immunol., 48, 2011
31BI	INTERLEUKIN-1 BETA (IL-1 BETA) (MUTANT WITH CYS 71 REPLACED BY SER) (C71S) 分子名称: INTERLEUKIN-1 BETA PRECURSOR 著者 Veerapandian, B, Poulos, T.L, Gilliland, G.L, Masui, Y, Hirai, Y. 登録日 1991-03-21 公開日 1992-04-15 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献
3F62	Crystal Structure of Human IL-18 in complex with Ectromelia virus IL-18 Binding Protein 分子名称: Interleukin 18 binding protein, Interleukin-18 著者 Krumm, B.E, Li, Y, Deng, J. 登録日 2008-11-05 公開日 2009-01-06 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural basis for antagonism of human interleukin 18 by poxvirus interleukin 18-binding protein. Proc.Natl.Acad.Sci.USA, 105, 2008
3LTQ	Structure of Interleukin 1B solved by SAD using an inserted Lanthanide Binding Tag 分子名称: ACETATE ION, Interleukin-1 beta, SULFATE ION, ... 著者 Peisach, E, Allen, K.N. 登録日 2010-02-16 公開日 2011-02-16 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Engineering encodable lanthanide-binding tags into loop regions of proteins. J.Am.Chem.Soc., 133, 2011
3NJ5	Crystal structure of chicken IL-1 hydrophobic cavity mutant 157 分子名称: IL-1 beta 著者 Yin, H.S, Chen, Y.W. 登録日 2010-06-17 公開日 2011-06-22 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 Structural and functional comparison of cytokine interleukin-1 beta from chicken and human Mol.Immunol., 48, 2011
3O4O	Crystal structure of an Interleukin-1 receptor complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-1 beta, ... 著者 Wang, X.Q, Wang, D.L, Zhang, S.Y, Li, L, Liu, X, Mei, K.R. 登録日 2010-07-27 公開日 2010-09-01 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Structural insights into the assembly and activation of IL-1beta with its receptors Nat.Immunol., 11, 2010
3POK	Interleukin-1-beta LBT L3 Mutant 分子名称: Interleukin-1 beta 著者 Barthelmes, K, Reynolds, A.M, Peisach, E, Jonker, H.R.A, DeNunzio, N.J, Allen, K.N, Imperiali, B, Schwalbe, H. 登録日 2010-11-22 公開日 2011-01-19 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Engineering encodable lanthanide-binding tags into loop regions of proteins. J.Am.Chem.Soc., 133, 2011
3WO2	Crystal structure of human interleukin-18 分子名称: 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, Interleukin-18, SULFATE ION 著者 Tsutsumi, N, Kimura, T, Arita, K, Ariyoshi, M, Ohnishi, H, Kondo, N, Shirakawa, M, Kato, Z, Tochio, H. 登録日 2013-12-19 公開日 2014-12-17 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.33 Å) 主引用文献 The structural basis for receptor recognition of human interleukin-18 Nat Commun, 5, 2014
3WO3	Crystal structure of IL-18 in complex with IL-18 receptor alpha 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Tsutsumi, N, Kimura, T, Arita, K, Ariyoshi, M, Ohnishi, H, Kondo, N, Shirakawa, M, Kato, Z, Tochio, H. 登録日 2013-12-19 公開日 2014-12-17 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 The structural basis for receptor recognition of human interleukin-18 Nat Commun, 5, 2014
3WO4	Crystal structure of the IL-18 signaling ternary complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Tsutsumi, N, Kimura, T, Arita, K, Ariyoshi, M, Ohnishi, H, Kondo, N, Shirakawa, M, Kato, Z, Tochio, H. 登録日 2013-12-19 公開日 2014-12-17 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 The structural basis for receptor recognition of human interleukin-18 Nat Commun, 5, 2014
41BI	INTERLEUKIN-1 BETA (IL-1 BETA) (MUTANT WITH CYS 8 REPLACED BY ALA (C8A) 分子名称: INTERLEUKIN-1 BETA 著者 Veerapandian, B, Poulos, T.L, Gilliland, G.L, Masui, Y, Hirai, Y. 登録日 1992-02-03 公開日 1992-04-15 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献
4DEP	Structure of the IL-1b signaling complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-1 beta, Interleukin-1 receptor accessory protein, ... 著者 Thomas, C, Garcia, K.C. 登録日 2012-01-21 公開日 2012-03-21 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structure of the activating IL-1 receptor signaling complex. Nat.Struct.Mol.Biol., 19, 2012
4EEE	Crystal Structure of YLDV 14L IL-18 Binding Protein in Complex with Human IL-18 分子名称: 14L protein, Interleukin-18 著者 Krumm, B.E, Xiang, Y, Deng, J. 登録日 2012-03-28 公開日 2012-09-26 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.71 Å) 主引用文献 A unique bivalent binding and inhibition mechanism by the yatapoxvirus interleukin 18 binding protein. Plos Pathog., 8, 2012
4EKX	Crystal Structure of YLDV 14L IL-18 Binding Protein in Complex with Human IL-18 分子名称: 14L protein, Interleukin-18 著者 Krumm, B.E, Xiang, Y, Deng, J. 登録日 2012-04-10 公開日 2012-09-26 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 A unique bivalent binding and inhibition mechanism by the yatapoxvirus interleukin 18 binding protein. Plos Pathog., 8, 2012
4G6J	Crystal structure of human IL-1beta in complex with the therapeutic antibody binding fragment of canakinumab 分子名称: Interleukin-1 beta, heavy chain of antibody binding fragment of canakinumab, light chain of antibody binding fragment of canakinumab 著者 Blech, M, Hoerer, S. 登録日 2012-07-19 公開日 2012-12-19 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 One traget-two different binding modes: Structural insights into gevokizumab and canakinumab interactions to interleukin-1beta J.Mol.Biol., 425, 2013
4G6M	Crystal structure of human IL-1beta in complex with therapeutic antibody binding fragment of gevokizumab 分子名称: Interleukin-1 beta, heavy chain of gevokizumab antibody binding fragment, light chain of gevokizumab antibody binding fragment 著者 Blech, M, Hoerer, S. 登録日 2012-07-19 公開日 2012-12-19 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 Crystal structure of human IL-1beta in complex with therapeutic antibody binding fragment of gevokizumab J.Mol.Biol., 425, 2013
4GAF	Crystal structure of EBI-005, a chimera of human IL-1beta and IL-1Ra, bound to human Interleukin-1 receptor type 1 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, EBI-005, Interleukin-1 receptor type 1, ... 著者 Hou, J, Townson, S.A, Kovalchin, J.T, Masci, A, Kiner, O, Shu, Y, King, B, Thomas, C, Garcia, K.C, Furfine, E.S, Barnes, T.M. 登録日 2012-07-25 公開日 2013-02-20 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Design of a superior cytokine antagonist for topical ophthalmic use. Proc.Natl.Acad.Sci.USA, 110, 2013
4GAI	Crystal structure of EBI-005, a chimera of human IL-1beta and IL-1Ra 分子名称: EBI-005 著者 Hou, J, Townson, S.A, Kovalchin, J.T, Masci, A, Kiner, O, Shu, Y, King, B, Thomas, C, Garcia, K.C, Furfine, E.S, Barnes, T.M. 登録日 2012-07-25 公開日 2013-02-20 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.49 Å) 主引用文献 Design of a superior cytokine antagonist for topical ophthalmic use. Proc.Natl.Acad.Sci.USA, 110, 2013
4HJJ	Structure Reveals Function of the Dual Variable Domain Immunoglobulin (DVD-Ig) Molecule 分子名称: Anti-IL12 Anti-IL18 DFab Heavy Chain, Anti-IL12 Anti-IL18 DFab Light Chain, CHLORIDE ION, ... 著者 Jakob, C.G, Edalji, R, Judge, R.A, DiGiammarino, E, Li, Y, Gu, J, Ghayur, T. 登録日 2012-10-12 公開日 2013-05-08 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure reveals function of the dual variable domain immunoglobulin (DVD-Ig[TM]) molecule MAbs, 5, 2013
4I1B	FUNCTIONAL IMPLICATIONS OF INTERLEUKIN-1BETA BASED ON THE THREE-DIMENSIONAL STRUCTURE 分子名称: INTERLEUKIN-1 BETA 著者 Veerapandian, B, Poulos, T.L, Gilliland, G.L, Raag, R, Svensson, L.A, Masui, Y, Hirai, Y. 登録日 1990-03-27 公開日 1990-04-15 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Functional implications of interleukin-1 beta based on the three-dimensional structure. Proteins, 12, 1992
4IZE	Crystal Structure of IL-36gamma 分子名称: Interleukin-36 gamma 著者 Guenther, S, Sundberg, E.J. 登録日 2013-01-29 公開日 2014-06-25 最終更新日 2014-07-16 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Molecular Determinants of Agonist and Antagonist Signaling through the IL-36 Receptor. J.Immunol., 193, 2014
4P0J	Crystal Structure of Loop-Swapped Interleukin-36Ra 分子名称: Interleukin-36 receptor antagonist/Interleukin-36 gamma chimera protein 著者 Guenther, S, Sundberg, E.J. 登録日 2014-02-21 公開日 2014-06-25 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.298 Å) 主引用文献 Molecular Determinants of Agonist and Antagonist Signaling through the IL-36 Receptor. J Immunol., 193, 2014
4P0K	Crystal Structure of Double Loop-Swapped Interleukin-36Ra 分子名称: Interleukin-36 receptor antagonist/Interleukin-36 gamma chimera protein 著者 Guenther, S, Sundberg, E.J. 登録日 2014-02-21 公開日 2014-06-25 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Molecular Determinants of Agonist and Antagonist Signaling through the IL-36 Receptor. J Immunol., 193, 2014

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